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Gene: Nfs1 (nitrogen fixation gene 1 (S. cerevisiae)) Mus musculus
Symbol: Nfs1
Name: nitrogen fixation gene 1 (S. cerevisiae)
Description: Predicted to have cysteine desulfurase activity and protein homodimerization activity. Involved in iron incorporation into metallo-sulfur cluster. Localizes to the mitochondrial matrix and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human NFS1 (NFS1 cysteine desulfurase); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; thiamine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA987187; cysteine desulfurase, mitochondrial; m-Nfs1; m-Nfsl; nifS-like (sic); nitrogen fixation gene, yeast homolog 1
Homo sapiens (human) : NFS1 (NFS1 cysteine desulfurase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfs1 (NFS1 cysteine desulfurase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfs1 (NFS1 cysteine desulfurase)
Pan paniscus (bonobo/pygmy chimpanzee) : NFS1 (NFS1 cysteine desulfurase)
Canis lupus familiaris (dog) : NFS1 (NFS1 cysteine desulfurase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfs1 (NFS1 cysteine desulfurase)
Sus scrofa (pig) : NFS1 (NFS1 cysteine desulfurase)
Chlorocebus sabaeus (African green monkey) : NFS1 (NFS1 cysteine desulfurase)
Heterocephalus glaber (naked mole-rat) : Nfs1 (NFS1 cysteine desulfurase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2156,123,639 - 156,144,186 (-)EnsemblGRCm38mm10GRCm38
GRCm382156,123,637 - 156,144,202 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372155,949,373 - 155,969,922 (-)NCBIGRCm37mm9NCBIm37
MGSCv362155,815,090 - 155,835,626 (-)NCBImm8
Celera2162,059,133 - 162,079,762 (-)NCBICelera
Cytogenetic Map2 H1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nfs1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734360
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.