Symbol:
RAB38
Name:
RAB38, member RAS oncogene family
Description:
Exhibits several functions, including AP-1 adaptor complex binding activity; AP-3 adaptor complex binding activity; and BLOC-2 complex binding activity. Involved in several processes, including endosome to melanosome transport; melanosome assembly; and phagosome acidification. Localizes to several cellular components, including cytoplasmic vesicle; lysosome; and mitochondria-associated endoplasmic reticulum membrane; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
melanoma antigen NY-MEL-1; NY-MEL-1; Rab-related GTP-binding protein; rab38, member of ras oncogene family; ras-related protein Rab-38; rrGTPbp
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Rab38 (RAB38, member RAS oncogene family) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Rab38 (RAB38, member RAS oncogene family) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):
Rab38 (RAB38, member RAS oncogene family) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
RAB38 (RAB38, member RAS oncogene family) NCBI
Ortholog
Canis lupus familiaris (dog):
RAB38 (RAB38, member RAS oncogene family) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rab38 (RAB38, member RAS oncogene family) NCBI
Ortholog
Sus scrofa (pig):
RAB38 (RAB38, member RAS oncogene family) HGNC
Ensembl, NCBI, OrthoDB
Chlorocebus sabaeus (African green monkey):
RAB38 (RAB38, member RAS oncogene family) NCBI
Ortholog
Heterocephalus glaber (naked mole-rat):
Rab38 (RAB38, member RAS oncogene family) NCBI
Ortholog
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rab38 (RAB38, member RAS oncogene family)
Alliance
DIOPT (PANTHER|HGNC|Ensembl Compara|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Mus musculus (house mouse):
Rab38 (RAB38, member RAS oncogene family)
Alliance
DIOPT (PANTHER|HGNC|Ensembl Compara|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam|Roundup)
Danio rerio (zebrafish):
rab38b (RAB38b, member of RAS oncogene family)
Alliance
DIOPT (PANTHER|ZFIN|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|TreeFam)
Caenorhabditis elegans (roundworm):
glo-1
Alliance
DIOPT (OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam|Roundup)
Drosophila melanogaster (fruit fly):
Rab32
Alliance
DIOPT (TreeFam|Roundup|OrthoFinder)
Danio rerio (zebrafish):
rab38a (RAB38a, member RAS oncogene family)
Alliance
DIOPT (ZFIN|TreeFam)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 Ensembl 11 88,113,251 - 88,175,443 (-) Ensembl GRCh38 hg38 GRCh38 GRCh38 11 87,809,490 - 88,175,504 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 11 87,846,415 - 87,908,635 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 11 87,486,079 - 87,548,247 (-) NCBI NCBI36 hg18 NCBI36 Build 34 11 87,486,078 - 87,548,247 NCBI Celera 11 86,723,503 - 86,785,679 (+) NCBI Cytogenetic Map 11 q14.2 NCBI HuRef 11 84,086,688 - 84,148,798 (-) NCBI HuRef CHM1_1 11 87,729,200 - 87,791,404 (-) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression ISO RGD:628752 6480464 chlorcyclizine results in increased expression of RAB38 mRNA CTD PMID:21058326 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of RAB38 mRNA CTD PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of RAB38 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RAB38 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of RAB38 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:628752 6480464 Tetrachlorodibenzodioxin results in decreased expression of RAB38 mRNA CTD PMID:21215274 2,4-dinitrotoluene affects expression ISO RGD:628752 6480464 2, 4-dinitrotoluene affects the expression of RAB38 mRNA CTD PMID:21346803 3-chloropropane-1,2-diol decreases expression ISO RGD:628752 6480464 alpha-Chlorohydrin results in decreased expression of RAB38 mRNA CTD PMID:28522335 4,4'-sulfonyldiphenol increases expression ISO RGD:734296 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of RAB38 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide decreases expression ISO RGD:734296 6480464 Fenretinide results in decreased expression of RAB38 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression ISO RGD:628752 6480464 Propylthiouracil results in increased expression of RAB38 mRNA CTD PMID:24780913 acrylamide increases expression ISO RGD:628752 6480464 Acrylamide results in increased expression of RAB38 mRNA CTD PMID:28959563 aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of RAB38 gene CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:628752 6480464 Tretinoin results in increased expression of RAB38 mRNA CTD PMID:20488242 ammonium chloride affects expression ISO RGD:628752 6480464 Ammonium Chloride affects the expression of RAB38 mRNA CTD PMID:16483693 amphetamine increases expression ISO RGD:628752 6480464 Amphetamine results in increased expression of RAB38 mRNA CTD PMID:30779732 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of RAB38 mRNA CTD PMID:20064835 , PMID:30453624 bisphenol A decreases expression ISO RGD:628752 6480464 bisphenol A results in decreased expression of RAB38 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:628752 6480464 bisphenol A results in increased expression of RAB38 mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:734296 6480464 bisphenol A results in increased expression of RAB38 mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:734296 6480464 bisphenol F results in increased expression of RAB38 mRNA CTD PMID:30951980 buspirone decreases expression ISO RGD:628752 6480464 Buspirone results in decreased expression of RAB38 mRNA CTD PMID:24136188 butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of RAB38 mRNA CTD PMID:29432896 chloropicrin decreases expression EXP 6480464 chloropicrin results in decreased expression of RAB38 mRNA CTD PMID:26352163 dehydroepiandrosterone decreases expression ISO RGD:628752 6480464 Dehydroepiandrosterone results in decreased expression of RAB38 mRNA CTD PMID:16940010 dexamethasone decreases expression ISO RGD:734296 6480464 Dexamethasone results in decreased expression of RAB38 mRNA CTD PMID:22733784 dibenz[a,h]anthracene decreases expression ISO RGD:734296 6480464 1 more ... CTD PMID:26377693 dichloroacetic acid decreases expression ISO RGD:734296 6480464 Dichloroacetic Acid results in decreased expression of RAB38 mRNA CTD PMID:28962523 diethylstilbestrol decreases expression ISO RGD:628752 6480464 Diethylstilbestrol results in decreased expression of RAB38 mRNA CTD PMID:17005392 dioxygen decreases expression ISO RGD:734296 6480464 Oxygen deficiency results in decreased expression of RAB38 mRNA CTD PMID:20880076 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB38 mRNA CTD PMID:27188386 endosulfan decreases expression ISO RGD:628752 6480464 Endosulfan results in decreased expression of RAB38 mRNA CTD PMID:29391264 flutamide decreases expression ISO RGD:628752 6480464 Flutamide results in decreased expression of RAB38 mRNA CTD PMID:24793618 genistein multiple interactions ISO RGD:628752 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of RAB38 mRNA CTD PMID:21782745 glafenine decreases expression ISO RGD:628752 6480464 Glafenine results in decreased expression of RAB38 mRNA CTD PMID:24136188 glycidol increases expression ISO RGD:628752 6480464 glycidol results in increased expression of RAB38 mRNA CTD PMID:24395379 GW 4064 increases expression ISO RGD:734296 6480464 GW 4064 results in increased expression of RAB38 mRNA CTD PMID:26655953 isobutanol multiple interactions EXP 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of RAB38 mRNA CTD PMID:29432896 isotretinoin decreases expression EXP 6480464 Isotretinoin results in decreased expression of RAB38 mRNA CTD PMID:20436886 leflunomide decreases expression ISO RGD:628752 6480464 leflunomide results in decreased expression of RAB38 mRNA CTD PMID:24136188 methoxychlor multiple interactions ISO RGD:628752 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of RAB38 mRNA CTD PMID:21782745 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of RAB38 mRNA CTD PMID:23179753 methylphenidate increases expression ISO RGD:734296 6480464 Methylphenidate results in increased expression of RAB38 mRNA CTD PMID:22470460 nefazodone decreases expression ISO RGD:628752 6480464 nefazodone results in decreased expression of RAB38 mRNA CTD PMID:24136188 nimesulide decreases expression ISO RGD:628752 6480464 nimesulide results in decreased expression of RAB38 mRNA CTD PMID:24136188 oxycodone decreases expression ISO RGD:628752 6480464 Oxycodone results in decreased expression of RAB38 mRNA CTD PMID:23439660 ozone decreases expression ISO RGD:628752 6480464 Ozone results in decreased expression of RAB38 mRNA CTD PMID:16330353 paracetamol affects expression ISO RGD:734296 6480464 Acetaminophen affects the expression of RAB38 mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of RAB38 mRNA CTD PMID:22230336 perfluorooctanoic acid decreases expression ISO RGD:628752 6480464 perfluorooctanoic acid results in decreased expression of RAB38 mRNA CTD PMID:19162173 pirinixic acid decreases expression ISO RGD:628752 6480464 pirinixic acid results in decreased expression of RAB38 mRNA CTD PMID:19162173 potassium chromate increases expression EXP 6480464 potassium chromate(VI) results in increased expression of RAB38 mRNA CTD PMID:22714537 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB38 mRNA CTD PMID:27188386 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of RAB38 mRNA, Silicon Dioxide results in decreased expression of RAB38 mRNA CTD PMID:25351596 , PMID:25895662 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of RAB38 mRNA CTD PMID:28595984 tetrachloromethane decreases expression ISO RGD:628752 6480464 Carbon Tetrachloride results in decreased expression of RAB38 mRNA CTD PMID:31150632 thapsigargin decreases expression ISO RGD:734296 6480464 Thapsigargin results in decreased expression of RAB38 protein CTD PMID:24648495 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of RAB38 mRNA CTD PMID:29453283 tipifarnib increases expression ISO RGD:628752 6480464 tipifarnib results in increased expression of RAB38 mRNA CTD PMID:16403772 triclosan increases expression EXP 6480464 Triclosan results in increased expression of RAB38 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:734296 6480464 trimellitic anhydride results in increased expression of RAB38 mRNA CTD PMID:19042947 valproic acid affects expression ISO RGD:734296 6480464 Valproic Acid affects the expression of RAB38 mRNA CTD PMID:17292431 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of RAB38 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB38 mRNA CTD PMID:27188386 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of RAB38 mRNA CTD PMID:25979313 vorinostat increases expression EXP 6480464 vorinostat results in increased expression of RAB38 mRNA CTD PMID:27188386 
Gene-Chemical Interaction Annotations
