Uba3 (ubiquitin-like modifier activating enzyme 3) - Rat Genome Database

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Gene: Uba3 (ubiquitin-like modifier activating enzyme 3) Mus musculus
Analyze
Symbol: Uba3
Name: ubiquitin-like modifier activating enzyme 3
RGD ID: 734283
MGI Page MGI
Description: Enables NEDD8 activating enzyme activity. Acts upstream of or within endomitotic cell cycle and regulation of cell cycle. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in embryo; eye; limb; and limb mesenchyme. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A830034N06Rik; AI256736; AI848246; AW546539; NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1C; RIKEN cDNA A830034N06 gene; Ube1c; ubiquitin activating enzyme 3; ubiquitin-activating enzyme 3; ubiquitin-activating enzyme E1C; ubiquitin-like modifier-activating enzyme 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm14538   Gm17213  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,160,593 - 97,182,608 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,160,631 - 97,182,608 (-)EnsemblGRCm39 Ensembl
GRCm38697,183,632 - 97,205,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,183,670 - 97,205,647 (-)EnsemblGRCm38mm10GRCm38
MGSCv37697,133,810 - 97,155,636 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,149,491 - 97,170,806 (-)NCBIMGSCv36mm8
Celera699,042,865 - 99,064,781 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleus  (IBA,IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The activating enzyme of NEDD8 inhibits steroid receptor function. Fan M, etal., Mol Endocrinol 2002 Feb;16(2):315-30.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10207026   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11696557   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:16481745   PMID:16602821   PMID:18799693   PMID:19245792   PMID:20059953   PMID:20937703   PMID:21677750   PMID:21873635   PMID:27593482   PMID:30462731   PMID:31941714  
PMID:32325033   PMID:34506605  


Genomics

Comparative Map Data
Uba3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,160,593 - 97,182,608 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,160,631 - 97,182,608 (-)EnsemblGRCm39 Ensembl
GRCm38697,183,632 - 97,205,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,183,670 - 97,205,647 (-)EnsemblGRCm38mm10GRCm38
MGSCv37697,133,810 - 97,155,636 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,149,491 - 97,170,806 (-)NCBIMGSCv36mm8
Celera699,042,865 - 99,064,781 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.9NCBI
UBA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38369,054,730 - 69,080,373 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl369,054,730 - 69,080,408 (-)EnsemblGRCh38hg38GRCh38
GRCh37369,103,881 - 69,129,524 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,186,571 - 69,212,214 (-)NCBINCBI36Build 36hg18NCBI36
Build 34369,186,571 - 69,212,214NCBI
Celera369,031,987 - 69,057,632 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef369,104,953 - 69,130,599 (-)NCBIHuRef
CHM1_1369,055,090 - 69,080,736 (-)NCBICHM1_1
T2T-CHM13v2.0369,091,517 - 69,117,165 (-)NCBIT2T-CHM13v2.0
Uba3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84131,346,219 - 131,367,378 (-)NCBIGRCr8
mRatBN7.24129,789,526 - 129,810,707 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,789,204 - 129,810,606 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4135,214,153 - 135,235,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04130,995,195 - 131,016,292 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04129,613,140 - 129,634,237 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04129,548,411 - 129,569,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,548,416 - 129,569,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,051,838 - 194,072,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,902,438 - 131,924,610 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,147,288 - 132,169,460 (-)NCBI
Celera4118,665,559 - 118,686,969 (-)NCBICelera
Cytogenetic Map4q34NCBI
Uba3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,780,730 - 18,801,266 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,781,015 - 18,801,266 (+)NCBIChiLan1.0ChiLan1.0
UBA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2269,010,165 - 69,035,897 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1369,014,952 - 69,043,481 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0368,990,760 - 69,016,377 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,357,665 - 70,383,166 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,358,371 - 70,383,117 (-)Ensemblpanpan1.1panPan2
UBA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,657,758 - 22,682,134 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,657,817 - 22,681,447 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,632,410 - 22,656,797 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,683,590 - 22,708,036 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,683,646 - 22,708,036 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12022,377,507 - 22,401,872 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,720,892 - 22,745,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,790,714 - 22,815,179 (+)NCBIUU_Cfam_GSD_1.0
Uba3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,555,314 - 1,574,521 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366031,555,548 - 1,577,438 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366031,555,274 - 1,574,521 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,477,458 - 50,504,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,479,264 - 50,504,901 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,560,074 - 55,585,710 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,080,972 - 30,106,450 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2230,080,863 - 30,106,419 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041136,686,030 - 136,711,534 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uba3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247733,622,362 - 3,646,980 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247733,623,295 - 3,646,974 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:641
Count of miRNA genes:241
Interacting mature miRNAs:286
Transcripts:ENSMUST00000089287, ENSMUST00000164744
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532719Sluc45_msusceptibility to lung cancer 45 (mouse)69258428798235894Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined688982366122982564Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687480321121480516Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686783787113521563Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
4141578Obrq1_mobesity resistance QTL 1 (mouse)Not determined92584287111981699Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse

Markers in Region
AW546539  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38697,184,410 - 97,184,558UniSTSGRCm38
GRCm38X20,529,785 - 20,529,927UniSTSGRCm38
MGSCv37697,134,404 - 97,134,552UniSTSGRCm37
MGSCv37X20,106,911 - 20,107,053UniSTSGRCm37
Celera699,043,459 - 99,043,607UniSTS
CeleraX18,661,102 - 18,661,244UniSTS
Cytogenetic Map6D3UniSTS
Whitehead/MRC_RH6987.45UniSTS
AI848246  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38697,184,390 - 97,184,509UniSTSGRCm38
MGSCv37697,134,384 - 97,134,503UniSTSGRCm37
Celera699,043,439 - 99,043,558UniSTS
Cytogenetic Map6D3UniSTS
Whitehead/MRC_RH6987.65UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC155724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF077330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY029181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY639644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF928750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JC212135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000089287   ⟹   ENSMUSP00000086701
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,160,968 - 97,182,608 (-)Ensembl
GRCm38.p6 Ensembl697,184,007 - 97,205,647 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164744   ⟹   ENSMUSP00000130954
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,160,631 - 97,182,521 (-)Ensembl
GRCm38.p6 Ensembl697,183,670 - 97,205,560 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203215
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,181,052 - 97,182,529 (-)Ensembl
GRCm38.p6 Ensembl697,204,091 - 97,205,568 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204056   ⟹   ENSMUSP00000145309
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,160,779 - 97,182,520 (-)Ensembl
GRCm38.p6 Ensembl697,183,818 - 97,205,559 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,179,975 - 97,182,526 (-)Ensembl
GRCm38.p6 Ensembl697,203,014 - 97,205,565 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204917
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl697,172,275 - 97,174,454 (-)Ensembl
GRCm38.p6 Ensembl697,195,314 - 97,197,493 (-)Ensembl
RefSeq Acc Id: NM_001111106   ⟹   NP_001104576
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,593 - 97,182,608 (-)NCBI
GRCm38697,183,632 - 97,205,647 (-)NCBI
MGSCv37697,133,810 - 97,155,636 (-)RGD
Celera699,042,681 - 99,064,786 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001301857   ⟹   NP_001288786
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,593 - 97,182,608 (-)NCBI
GRCm38697,183,632 - 97,205,647 (-)NCBI
Celera699,042,681 - 99,064,786 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001301858   ⟹   NP_001288787
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,593 - 97,182,608 (-)NCBI
GRCm38697,183,632 - 97,205,647 (-)NCBI
Celera699,042,681 - 99,064,786 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001301859   ⟹   NP_001288788
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,162,535 - 97,182,608 (-)NCBI
GRCm38697,185,574 - 97,205,647 (-)NCBI
Celera699,042,681 - 99,064,786 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011666   ⟹   NP_035796
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,593 - 97,182,608 (-)NCBI
GRCm38697,183,632 - 97,205,647 (-)NCBI
MGSCv37697,133,810 - 97,155,636 (-)RGD
Celera699,042,681 - 99,064,786 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011241290   ⟹   XP_011239592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,931 - 97,182,308 (-)NCBI
GRCm38697,183,997 - 97,205,347 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255315   ⟹   XP_030111175
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,931 - 97,182,549 (-)NCBI
GRCm38697,183,997 - 97,205,588 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255316   ⟹   XP_030111176
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,931 - 97,182,601 (-)NCBI
GRCm38697,183,997 - 97,205,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036166022   ⟹   XP_036021915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,160,931 - 97,182,543 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035796   ⟸   NM_011666
- Peptide Label: isoform 1
- UniProtKB: Q3TG68 (UniProtKB/Swiss-Prot),   O88598 (UniProtKB/Swiss-Prot),   Q9D6B7 (UniProtKB/Swiss-Prot),   Q8C878 (UniProtKB/Swiss-Prot),   Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104576   ⟸   NM_001111106
- Peptide Label: isoform 2
- UniProtKB: Q3TL72 (UniProtKB/TrEMBL),   Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288787   ⟸   NM_001301858
- Peptide Label: isoform 4
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288786   ⟸   NM_001301857
- Peptide Label: isoform 3
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288788   ⟸   NM_001301859
- Peptide Label: isoform 5
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239592   ⟸   XM_011241290
- Peptide Label: isoform X1
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111176   ⟸   XM_030255316
- Peptide Label: isoform X2
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030111175   ⟸   XM_030255315
- Peptide Label: isoform X1
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000130954   ⟸   ENSMUST00000164744
Ensembl Acc Id: ENSMUSP00000145309   ⟸   ENSMUST00000204056
Ensembl Acc Id: ENSMUSP00000086701   ⟸   ENSMUST00000089287
RefSeq Acc Id: XP_036021915   ⟸   XM_036166022
- Peptide Label: isoform X1
- UniProtKB: Q66JT6 (UniProtKB/TrEMBL)
Protein Domains
E2 binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C878-F1-model_v2 AlphaFold Q8C878 1-462 view protein structure

Promoters
RGD ID:6840147
Promoter ID:MM_KWN:47004
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001111106,   NM_011666,   UC009DAL.1,   UC009DAN.1,   UC009DAO.1,   UC009DAQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36697,155,479 - 97,155,979 (-)MPROMDB
RGD ID:6890516
Promoter ID:EPDNEW_M8709
Type:multiple initiation site
Name:Uba3_1
Description:Mus musculus ubiquitin-like modifier activating enzyme 3 , transcriptvariant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38697,205,558 - 97,205,618EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341217 AgrOrtholog
Ensembl Genes ENSMUSG00000030061 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000089287 ENTREZGENE
  ENSMUST00000089287.7 UniProtKB/Swiss-Prot
  ENSMUST00000164744 ENTREZGENE
  ENSMUST00000164744.8 UniProtKB/TrEMBL
  ENSMUST00000204056.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.520 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro E2-binding UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  ThiF/MoeB/HesA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThiF_NAD_FAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ub_act_enz_dom_a_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Uba3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-activating_enz UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ-activ_enz_E1_Cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1341217 ENTREZGENE
NCBI Gene 22200 ENTREZGENE
PANTHER PTHR10953 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10953:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam E2_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThiF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uba3 PhenoGen
PROSITE UBIQUITIN_ACTIVAT_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART E2_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF69572 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SVZ2_MOUSE UniProtKB/TrEMBL
  O88598 ENTREZGENE
  Q3TG68 ENTREZGENE
  Q3TL72 ENTREZGENE, UniProtKB/TrEMBL
  Q66JT6 ENTREZGENE, UniProtKB/TrEMBL
  Q8C878 ENTREZGENE
  Q9D6B7 ENTREZGENE
  UBA3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O88598 UniProtKB/Swiss-Prot
  Q3TG68 UniProtKB/Swiss-Prot
  Q9D6B7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Uba3  ubiquitin-like modifier activating enzyme 3  A830034N06Rik  RIKEN cDNA A830034N06 gene  Data merged from RGD:1609466 737654 PROVISIONAL