Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of AP3M1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of AP3M1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AP3M1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of AP3M1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AP3M1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of AP3M1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of AP3M1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AP3M1 mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of AP3M1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of AP3M1 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | EXP | | 6480464 | beta-methylcholine affects the expression of AP3M1 mRNA | CTD | PMID:21179406 | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of AP3M1 protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of AP3M1 mRNA | CTD | PMID:26251327 | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of AP3M1 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of AP3M1 mRNA | CTD | PMID:18648102 | acrylamide | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of AP3M1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of AP3M1 mRNA | CTD | PMID:19770486 | ammonium chloride | affects expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of AP3M1 mRNA | CTD | PMID:16483693 | antimycin A | decreases expression | EXP | | 6480464 | Antimycin A results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of AP3M1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of AP3M1 mRNA | CTD | PMID:22228805 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of AP3M1 protein | CTD | PMID:34186270 | cadmium dichloride | decreases methylation | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of AP3M1 promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of AP3M1 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to AP3M1 gene] | CTD | PMID:28238834 | copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of AP3M1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of AP3M1 mRNA | CTD | PMID:20971185 | crocidolite asbestos | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of AP3M1 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of AP3M1 mRNA | CTD | PMID:19770486 | deguelin | decreases expression | EXP | | 6480464 | deguelin results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | dibutyl phthalate | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of AP3M1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of AP3M1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dibutyl phthalate | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of AP3M1 mRNA | CTD | PMID:21266533 | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of AP3M1 mRNA | CTD | PMID:36621641 | dioxygen | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of AP3M1 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AP3M1 mRNA | CTD | PMID:27188386 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AP3M1 mRNA | CTD | PMID:27188386 | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of AP3M1 mRNA | CTD | PMID:26272509 | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of AP3M1 mRNA | CTD | PMID:23649840 | fenpyroximate | decreases expression | EXP | | 6480464 | fenpyroximate results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | flutamide | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of AP3M1 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of AP3M1 mRNA | CTD | PMID:25629700 | furan | increases methylation | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | furan results in increased methylation of AP3M1 gene | CTD | PMID:22079235 | gentamycin | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of AP3M1 mRNA | CTD | PMID:22061828 | gentamycin | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of AP3M1 mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of AP3M1 protein | CTD | PMID:32959892 | ketamine | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of AP3M1 mRNA | CTD | PMID:20080153 | ketoconazole | decreases expression | EXP | | 6480464 | Ketoconazole results in decreased expression of AP3M1 mRNA | CTD | PMID:36621641 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of AP3M1 mRNA | CTD | PMID:28903495 | ozone | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of AP3M1 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of AP3M1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of AP3M1 mRNA | CTD | PMID:33387578 | pentachlorophenol | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of AP3M1 mRNA | CTD | PMID:23892564 | phenobarbital | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of AP3M1 mRNA | CTD | PMID:19270015 | picoxystrobin | decreases expression | EXP | | 6480464 | picoxystrobin results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | pirinixic acid | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of AP3M1 mRNA | CTD | PMID:18445702 | pirinixic acid | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AP3M1 mRNA | CTD | PMID:19710929 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of AP3M1 mRNA | CTD | PMID:19162173 | reactive oxygen species | affects expression | EXP | | 6480464 | Reactive Oxygen Species affects the expression of AP3M1 mRNA | CTD | PMID:25800948 | resveratrol | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | resveratrol results in increased expression of AP3M1 protein | CTD | PMID:25505154 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | EXP | | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | affects expression | EXP | | 6480464 | sodium arsenite affects the expression of AP3M1 mRNA | CTD | PMID:20816728 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of AP3M1 protein | CTD | PMID:30528433 | sodium fluoride | increases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of AP3M1 protein | CTD | PMID:28918527 | Soman | decreases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of AP3M1 mRNA | CTD | PMID:19281266 | sulforaphane | multiple interactions | ISO | Ap3m1 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of AP3M1 mRNA | CTD | PMID:30529165 | tamoxifen | affects expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of AP3M1 mRNA | CTD | PMID:17555576 | tebufenpyrad | decreases expression | EXP | | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of AP3M1 mRNA | CTD | PMID:33512557 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of AP3M1 mRNA | CTD | PMID:31758290 | testosterone | decreases expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Testosterone results in decreased expression of AP3M1 mRNA | CTD | PMID:21669218 | triphenyl phosphate | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of AP3M1 mRNA | CTD | PMID:30589522 | valproic acid | affects expression | ISO | Ap3m1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of AP3M1 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of AP3M1 mRNA | CTD | PMID:28001369 | vinclozolin | increases expression | ISO | Ap3m1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of AP3M1 mRNA | CTD | PMID:23555832 | |