Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Fgf11 (Rattus norvegicus) | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of FGF11 mRNA | CTD | PMID:27840820 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FGF11 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of FGF11 mRNA | CTD | PMID:30723492 | 17beta-estradiol | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Arsenic co-treated with Estradiol] results in increased expression of FGF11 mRNA | CTD | PMID:33047385 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGF11 mRNA | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGF11 mRNA | CTD | PMID:33387578 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of FGF11 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of FGF11 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of FGF11 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in decreased expression of FGF11 mRNA | CTD | PMID:33354967 | ammonium chloride | affects expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of FGF11 mRNA | CTD | PMID:16483693 | arsane | affects expression | ISO | FGF11 (Homo sapiens) | 6480464 | Arsenic affects the expression of FGF11 protein | CTD | PMID:24675094 | arsane | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Arsenic co-treated with Estradiol] results in increased expression of FGF11 mRNA | CTD | PMID:33047385 | arsenic atom | affects expression | ISO | FGF11 (Homo sapiens) | 6480464 | Arsenic affects the expression of FGF11 protein | CTD | PMID:24675094 | arsenic atom | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Arsenic co-treated with Estradiol] results in increased expression of FGF11 mRNA | CTD | PMID:33047385 | benzo[a]pyrene | affects methylation | ISO | FGF11 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FGF11 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | FGF11 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FGF11 3' UTR and Benzo(a)pyrene results in increased methylation of FGF11 exon | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | decreases expression | EXP | | 6480464 | Mustard Gas results in decreased expression of FGF11 mRNA | CTD | PMID:15674843 | bisphenol A | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of FGF11 mRNA | CTD | PMID:25181051 more ... | CGP 52608 | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FGF11 gene] | CTD | PMID:28238834 | chlorpyrifos | affects expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Chlorpyrifos affects the expression of FGF11 mRNA | CTD | PMID:17589599 and PMID:18502319 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of FGF11 mRNA | CTD | PMID:28472532 | cisplatin | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FGF11 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | ISO | Fgf11 (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of FGF11 mRNA | CTD | PMID:26033743 | copper atom | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in increased expression of FGF11 mRNA | CTD | PMID:30911355 | copper atom | increases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of FGF11 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | ISO | Fgf11 (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of FGF11 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in increased expression of FGF11 mRNA | CTD | PMID:30911355 | copper(0) | increases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of FGF11 mRNA | CTD | PMID:26033743 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FGF11 mRNA | CTD | PMID:21266533 | dimethylarsinic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of FGF11 mRNA | CTD | PMID:34876320 | dioxygen | increases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of FGF11 mRNA | CTD | PMID:20042640 more ... | dioxygen | multiple interactions | ISO | Fgf11 (Rattus norvegicus) | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of FGF11 mRNA | CTD | PMID:33729688 | dorsomorphin | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF11 mRNA | CTD | PMID:27188386 | entinostat | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF11 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | FGF11 (Homo sapiens) | 6480464 | entinostat results in increased expression of FGF11 mRNA | CTD | PMID:26272509 and PMID:27188386 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of FGF11 mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of FGF11 mRNA | CTD | PMID:21867686 | furan | increases methylation | ISO | Fgf11 (Rattus norvegicus) | 6480464 | furan results in increased methylation of FGF11 gene | CTD | PMID:22079235 | methylarsonic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of FGF11 mRNA | CTD | PMID:34876320 | N-methyl-4-phenylpyridinium | increases expression | ISO | FGF11 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of FGF11 mRNA | CTD | PMID:24810058 | nickel dichloride | increases expression | ISO | FGF11 (Homo sapiens) | 6480464 | nickel chloride results in increased expression of FGF11 mRNA | CTD | PMID:21455298 | paracetamol | decreases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FGF11 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of FGF11 mRNA | CTD | PMID:33387578 | resveratrol | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of FGF11 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | FGF11 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF11 mRNA | CTD | PMID:27188386 | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of FGF11 mRNA | CTD | PMID:34876320 | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of FGF11 mRNA | CTD | PMID:34876320 | sunitinib | increases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of FGF11 mRNA | CTD | PMID:31533062 | thimerosal | decreases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of FGF11 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | ISO | Fgf11 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of FGF11 mRNA | CTD | PMID:34492290 | tremolite asbestos | increases expression | EXP | | 6480464 | tremolite results in increased expression of FGF11 mRNA | CTD | PMID:29279043 | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of FGF11 mRNA | CTD | PMID:19042947 | urethane | decreases expression | ISO | FGF11 (Homo sapiens) | 6480464 | Urethane results in decreased expression of FGF11 mRNA | CTD | PMID:28818685 | vorinostat | decreases expression | ISO | FGF11 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of FGF11 mRNA | CTD | PMID:27188386 | |