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Gene: Rtn4r (reticulon 4 receptor) Mus musculus
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Symbol: Rtn4r
Name: reticulon 4 receptor
Description: Exhibits chondroitin sulfate binding activity; heparin binding activity; and neuregulin receptor activity. Involved in nervous system development; neuronal signal transduction; and positive regulation of GTPase activity. Localizes to several cellular components, including the axonal growth cone; dendritic shaft; and neuronal cell body. Human ortholog(s) of this gene implicated in schizophrenia. Is expressed in several structures, including cardiovascular system; forelimb bud; genitourinary system; nervous system; and spleen. Orthologous to human RTN4R (reticulon 4 receptor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NgR; NgR1; nogo receptor; Nogo-66 receptor; nogo66 receptor-1; NOGOR; reticulon-4 receptor
Orthologs:
Homo sapiens (human) : RTN4R (reticulon 4 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rtn4r (reticulon 4 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtn4r (reticulon 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : RTN4R (reticulon 4 receptor)
Canis lupus familiaris (dog) : RTN4R (reticulon 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtn4r (reticulon 4 receptor)
Sus scrofa (pig) : RTN4R (reticulon 4 receptor)
Chlorocebus sabaeus (green monkey) : RTN4R (reticulon 4 receptor)
Heterocephalus glaber (naked mole-rat) : Rtn4r (reticulon 4 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1618,127,642 - 18,152,408 (+)Ensembl
GRCm381618,127,642 - 18,152,408 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371618,127,799 - 18,152,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv361618,041,269 - 18,065,971 (+)NCBImm8
Celera1618,700,292 - 18,725,154 (+)NCBICelera
Cytogenetic Map16 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rtn4r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734084
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.