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Gene: Rtn4r (reticulon 4 receptor) Mus musculus
Symbol: Rtn4r
Name: reticulon 4 receptor
Description: Exhibits chondroitin sulfate binding activity; heparin binding activity; and neuregulin receptor activity. Involved in nervous system development; neuronal signal transduction; and positive regulation of GTPase activity. Localizes to several cellular components, including the axonal growth cone; dendritic shaft; and neuronal cell body. Human ortholog(s) of this gene implicated in schizophrenia. Is expressed in several structures, including cardiovascular system; forelimb bud; genitourinary system; nervous system; and spleen. Orthologous to human RTN4R (reticulon 4 receptor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NgR; NgR1; nogo receptor; Nogo-66 receptor; nogo66 receptor-1; NOGOR; reticulon-4 receptor
Homo sapiens (human) : RTN4R (reticulon 4 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rtn4r (reticulon 4 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtn4r (reticulon 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : RTN4R (reticulon 4 receptor)
Canis lupus familiaris (dog) : RTN4R (reticulon 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtn4r (reticulon 4 receptor)
Sus scrofa (pig) : RTN4R (reticulon 4 receptor)
Chlorocebus sabaeus (green monkey) : RTN4R (reticulon 4 receptor)
Heterocephalus glaber (naked mole-rat) : Rtn4r (reticulon 4 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1618,127,642 - 18,152,408 (+)Ensembl
GRCm381618,127,642 - 18,152,408 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371618,127,799 - 18,152,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv361618,041,269 - 18,065,971 (+)NCBImm8
Celera1618,700,292 - 18,725,154 (+)NCBICelera
Cytogenetic Map16 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rtn4r
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734084
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.