Rcvrn (recoverin) - Rat Genome Database
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Gene: Rcvrn (recoverin) Mus musculus
Analyze
Symbol: Rcvrn
Name: recoverin
RGD ID: 734066
MGI Page MGI
Description: Exhibits calcium ion binding activity. Involved in phototransduction; regulation of calcium ion transport; and visual perception. Predicted to localize to dendrite. Is expressed in eye; photoreceptor layer; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human RCVRN (recoverin); PARTICIPATES IN calcium/calcium-mediated signaling pathway; visual phototransduction pathway; INTERACTS WITH genistein; lead diacetate; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 23 kDa photoreceptor cell-specific protein; cancer associated retinopathy protein; cancer-associated retinopathy protein; CAR; guanylate cyclase activator; MGC129468; S-mo; S-modulin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,586,152 - 67,594,181 (+)NCBIGRCm39mm39
GRCm381167,695,326 - 67,703,355 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,695,326 - 67,703,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,508,828 - 67,516,857 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,503,492 - 67,519,528 (+)NCBImm8
Celera1174,638,003 - 74,646,052 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell projection  (IEA)
dendrite  (ISO)
membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:1386025   PMID:7745609   PMID:7767000   PMID:8422501   PMID:11493566   PMID:12477932   PMID:14519497   PMID:15173221   PMID:15215744   PMID:15336959   PMID:15363391   PMID:15882641  
PMID:15930147   PMID:15961391   PMID:16110338   PMID:16182275   PMID:17092954   PMID:17480014   PMID:18094249   PMID:18198336   PMID:18265020   PMID:18308476   PMID:19279690   PMID:19389377  
PMID:19416500   PMID:20026326   PMID:20107049   PMID:20110327   PMID:20237275   PMID:20826655   PMID:21031137   PMID:21087508   PMID:21267068   PMID:21451052   PMID:21576358   PMID:21857657  
PMID:22222602   PMID:22258620   PMID:22323600   PMID:22627278   PMID:22880002   PMID:23001562   PMID:23136436   PMID:23142158   PMID:23172916   PMID:23223288   PMID:23935957   PMID:24453340  
PMID:24463367   PMID:25126785   PMID:25179941   PMID:25501893   PMID:25556712   PMID:25673692   PMID:25989023   PMID:26628093   PMID:26949938   PMID:27677711   PMID:28011038   PMID:28288836  
PMID:28356311   PMID:28579317   PMID:28760865   PMID:29435986   PMID:29922981   PMID:30127719   PMID:30367097   PMID:30635390   PMID:30718640   PMID:30924851   PMID:31002540   PMID:31155355  
PMID:31493975   PMID:32071204   PMID:32221352   PMID:32994318  


Genomics

Comparative Map Data
Rcvrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,586,152 - 67,594,181 (+)NCBIGRCm39mm39
GRCm381167,695,326 - 67,703,355 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,695,326 - 67,703,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,508,828 - 67,516,857 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,503,492 - 67,519,528 (+)NCBImm8
Celera1174,638,003 - 74,646,052 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.13NCBI
RCVRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl179,896,320 - 9,905,271 (-)EnsemblGRCh38hg38GRCh38
GRCh38179,896,320 - 9,905,271 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37179,799,637 - 9,808,588 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37179,801,027 - 9,808,684 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36179,741,752 - 9,749,409 (-)NCBINCBI36hg18NCBI36
Build 34179,741,751 - 9,749,409NCBI
Celera179,832,341 - 9,839,998 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef179,701,388 - 9,709,045 (-)NCBIHuRef
CHM1_1179,811,040 - 9,818,697 (-)NCBICHM1_1
Rcvrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21052,388,706 - 52,396,454 (+)NCBI
Rnor_6.0 Ensembl1054,246,250 - 54,253,996 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01054,246,250 - 54,253,996 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01053,992,826 - 54,000,572 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41054,409,087 - 54,416,833 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11054,422,709 - 54,430,456 (+)NCBI
Celera1051,569,938 - 51,577,684 (+)NCBICelera
Cytogenetic Map10q24NCBI
Rcvrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554677,220,237 - 7,236,450 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554677,220,237 - 7,236,450 (+)NCBIChiLan1.0ChiLan1.0
RCVRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11746,490,605 - 46,502,962 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1746,490,605 - 46,502,962 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01741,747,255 - 41,759,074 (+)NCBIMhudiblu_PPA_v0panPan3
RCVRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl534,323,576 - 34,330,667 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1534,323,580 - 34,330,667 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rcvrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365952,873,739 - 2,882,150 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RCVRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,740,642 - 54,750,716 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,740,642 - 54,752,291 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,498,861 - 57,510,068 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RCVRN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,236,647 - 9,246,994 (-)NCBI
ChlSab1.1 Ensembl169,237,001 - 9,246,490 (-)Ensembl
Rcvrn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478612,329,116 - 12,337,234 (-)NCBI

Position Markers
X66196  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B3UniSTS
cM Map1135.0UniSTS
Whitehead/MRC_RH11881.24UniSTS
RCV1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,695,507 - 67,695,783UniSTSGRCm38
MGSCv371167,509,009 - 67,509,285UniSTSGRCm37
Celera1174,638,184 - 74,638,460UniSTS
Cytogenetic Map11B3UniSTS
cM Map1135.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116315128768609504Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:167
Count of miRNA genes:150
Interacting mature miRNAs:158
Transcripts:ENSMUST00000021290
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000021290   ⟹   ENSMUSP00000021290
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1167,695,326 - 67,703,333 (+)Ensembl
RefSeq Acc Id: NM_009038   ⟹   NP_033064
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,586,152 - 67,594,181 (+)NCBI
GRCm381167,695,326 - 67,703,355 (+)ENTREZGENE
MGSCv371167,508,828 - 67,516,857 (+)RGD
Celera1174,638,003 - 74,646,052 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033064 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI10565 (Get FASTA)   NCBI Sequence Viewer  
  CAA46958 (Get FASTA)   NCBI Sequence Viewer  
  EDL10434 (Get FASTA)   NCBI Sequence Viewer  
  P34057 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033064   ⟸   NM_009038
- UniProtKB: P34057 (UniProtKB/Swiss-Prot),   Q2TB46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000021290   ⟸   ENSMUST00000021290
Protein Domains
EF-hand

Promoters
RGD ID:6821715
Promoter ID:MM_KWN:7959
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Brain
Transcripts:NM_009038
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361167,508,889 - 67,509,389 (+)MPROMDB
RGD ID:8675084
Promoter ID:EPDNEW_M15573
Type:initiation region
Name:Rcvrn_1
Description:Mus musculus recoverin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381167,695,345 - 67,695,405EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97883 AgrOrtholog
Ensembl Genes ENSMUSG00000020907 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000021290 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021290 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Recoverin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19674 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97883 ENTREZGENE
NCBI Gene 19674 ENTREZGENE
PANTHER PTHR23055 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rcvrn PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P34057 ENTREZGENE
  Q2TB46 ENTREZGENE, UniProtKB/TrEMBL
  RECO_MOUSE UniProtKB/Swiss-Prot