Gene: TRPC1 (transient receptor potential cation channel subfamily C member 1) Homo sapiens
Symbol: TRPC1
Name: transient receptor potential cation channel subfamily C member 1
Description: The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: capacitative calcium channel protein Trp1; HTRP-1; MGC133334; MGC133335; OTTHUMP00000214760; OTTHUMP00000214787; short transient receptor potential channel 1; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; transient receptor potential channel 1; transient receptor protein 1; TRP-1; TRP1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh383142,724,032 - 142,807,888 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373142,443,266 - 142,526,730 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363143,925,956 - 144,009,420 (+)NCBINCBI36hg18NCBI36
Build 343143,925,963 - 144,009,427NCBI
Celera3140,866,763 - 140,950,233 (+)NCBI
Cytogenetic Map3q23NCBI
HuRef3139,815,981 - 139,899,449 (+)NCBIHuRef
CHM1_13142,406,259 - 142,489,727 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRPC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734058
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE