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Gene: CUL5 (cullin 5) Homo sapiens
Symbol: CUL5
Name: cullin 5
Description: Exhibits ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Localizes to the Cul5-RING ubiquitin ligase complex and site of DNA damage; PARTICIPATES IN proteasome degradation pathway involving cullin-dependent ubiquitin ligases; neddylation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2-hydroxypropanoic acid; 5-fluorouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CUL-5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); VACM-1; VACM1; vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1
Mus musculus (house mouse) : Cul5 (cullin 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cul5 (cullin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul5 (cullin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL5 (cullin 5)
Canis lupus familiaris (dog) : CUL5 (cullin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul5 (cullin 5)
Sus scrofa (pig) : CUL5 (cullin 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811108,008,733 - 108,107,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711107,879,408 - 107,978,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,384,618 - 107,483,698 (+)NCBINCBI36hg18NCBI36
Build 3411107,384,854 - 107,482,773NCBI
Celera11105,033,798 - 105,132,859 (+)NCBI
Cytogenetic Map11q22.3NCBI
HuRef11103,804,481 - 103,903,597 (+)NCBIHuRef
CHM1_111107,762,661 - 107,861,678 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CUL5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733947
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.