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Gene: CUL5 (cullin 5) Homo sapiens
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Symbol: CUL5
Name: cullin 5
Description: Exhibits ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Localizes to the Cul5-RING ubiquitin ligase complex and site of DNA damage; PARTICIPATES IN proteasome degradation pathway involving cullin-dependent ubiquitin ligases; neddylation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2-hydroxypropanoic acid; 5-fluorouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CUL-5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); VACM-1; VACM1; vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1
Orthologs:
Mus musculus (house mouse) : Cul5 (cullin 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cul5 (cullin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul5 (cullin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL5 (cullin 5)
Canis lupus familiaris (dog) : CUL5 (cullin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul5 (cullin 5)
Sus scrofa (pig) : CUL5 (cullin 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811108,008,733 - 108,107,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711107,879,408 - 107,978,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,384,618 - 107,483,698 (+)NCBINCBI36hg18NCBI36
Build 3411107,384,854 - 107,482,773NCBI
Celera11105,033,798 - 105,132,859 (+)NCBI
Cytogenetic Map11q22.3NCBI
HuRef11103,804,481 - 103,903,597 (+)NCBIHuRef
CHM1_111107,762,661 - 107,861,678 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CUL5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733947
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.