Gene: HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1) Homo sapiens
Symbol: HCN1
Name: hyperpolarization activated cyclic nucleotide gated potassium channel 1
Description: The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BCNG-1; BCNG1; brain cyclic nucleotide gated channel 1; brain cyclic nucleotide-gated channel 1; EIEE24; HAC-2; hyperpolarization activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated potassium channel 1 (hcn1); OTTHUMP00000161806; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38545,254,950 - 45,696,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37545,255,052 - 45,696,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36545,295,109 - 45,731,977 (-)NCBINCBI36hg18NCBI36
Build 34545,297,729 - 45,731,977NCBI
Celera545,153,108 - 45,590,074 (-)NCBI
Cytogenetic Map5p12NCBI
HuRef545,207,222 - 45,649,517 (-)NCBIHuRef
CHM1_1545,254,898 - 45,696,071 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HCN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733930
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-02-19
Status: ACTIVE