Gucy2e (guanylate cyclase 2e) - Rat Genome Database

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Gene: Gucy2e (guanylate cyclase 2e) Mus musculus
Analyze
Symbol: Gucy2e
Name: guanylate cyclase 2e
RGD ID: 733871
MGI Page MGI
Description: Enables guanylate cyclase activity. Involved in cGMP biosynthetic process. Located in photoreceptor outer segment membrane. Is expressed in dorsal root ganglion; retina outer nuclear layer; and spinal cord. Used to study Leber congenital amaurosis 1 and cone-rod dystrophy 6. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 1; choroidal sclerosis; cone-rod dystrophy 6; congenital stationary night blindness; and retinitis pigmentosa. Orthologous to human GUCY2D (guanylate cyclase 2D, retinal).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC020186; cDNA sequence BC020186; GC-E; GC1; guanylyl cyclase 2e; guanylyl cyclase GC-E; retinal guanylyl cyclase 1; ROS-; ROS-GC1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,108,943 - 69,128,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,108,943 - 69,127,862 (-)EnsemblGRCm39 Ensembl
GRCm381169,218,117 - 69,237,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,218,117 - 69,237,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,031,619 - 69,050,524 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,039,230 - 69,052,840 (-)NCBIMGSCv36mm8
Celera1176,171,185 - 76,190,106 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Photoreceptor signaling: supporting vision across a wide range of light intensities. Arshavsky VY and Burns ME, J Biol Chem. 2012 Jan 13;287(3):1620-6. Epub 2011 Nov 10.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Clustering and frequency of mutations in the retinal guanylate cyclase (GUCY2D) gene in patients with dominant cone-rod dystrophies. Payne AM, etal., J Med Genet. 2001 Sep;38(9):611-4.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8838319   PMID:9888789   PMID:10349636   PMID:10407028   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14681479   PMID:15452041   PMID:15623748   PMID:16110338  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:16936082   PMID:17255100   PMID:17954614   PMID:19901021   PMID:20593011   PMID:20858907   PMID:20950332   PMID:21267068   PMID:21598940  
PMID:21677750   PMID:21778276   PMID:21873635   PMID:22508049   PMID:22570183   PMID:22623665   PMID:23082185   PMID:24027293   PMID:24260450   PMID:24457600   PMID:24550448   PMID:25616661  
PMID:26124274   PMID:26247368   PMID:26387748   PMID:26590321   PMID:27471269   PMID:27703005   PMID:29440533   PMID:30422870   PMID:31346032   PMID:32173907   PMID:32290105   PMID:32325033  
PMID:33171621   PMID:36293380   PMID:36698779   PMID:37033230  


Genomics

Comparative Map Data
Gucy2e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,108,943 - 69,128,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,108,943 - 69,127,862 (-)EnsemblGRCm39 Ensembl
GRCm381169,218,117 - 69,237,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,218,117 - 69,237,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,031,619 - 69,050,524 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,039,230 - 69,052,840 (-)NCBIMGSCv36mm8
Celera1176,171,185 - 76,190,106 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.51NCBI
GUCY2D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,002,615 - 8,020,342 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,002,615 - 8,020,342 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,905,933 - 7,923,660 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,846,713 - 7,864,382 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,846,716 - 7,864,382NCBI
Celera177,933,553 - 7,951,223 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,800,798 - 7,818,448 (+)NCBIHuRef
CHM1_1177,914,754 - 7,932,424 (+)NCBICHM1_1
T2T-CHM13v2.0177,908,012 - 7,925,755 (+)NCBIT2T-CHM13v2.0
Gucy2d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,453,753 - 54,478,639 (-)NCBIGRCr8
mRatBN7.21053,954,918 - 53,975,576 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,959,010 - 53,974,067 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,620,762 - 58,635,826 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,109,376 - 58,124,440 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,617,409 - 53,632,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,835,695 - 55,851,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,835,695 - 55,851,235 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,578,751 - 55,594,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,012,236 - 56,027,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,025,858 - 56,040,913 (-)NCBI
Celera1053,117,455 - 53,132,510 (-)NCBICelera
Cytogenetic Map10q24NCBI
Gucy2d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,938,057 - 8,949,684 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,938,057 - 8,949,684 (-)NCBIChiLan1.0ChiLan1.0
GUCY2D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,600,369 - 15,617,078 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,566,370 - 17,585,192 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,037,301 - 8,051,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1178,023,248 - 8,036,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,023,519 - 8,036,065 (+)Ensemblpanpan1.1panPan2
GUCY2D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,844,033 - 32,859,263 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,844,033 - 32,857,687 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,980,192 - 32,995,463 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,946,524 - 32,962,026 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,946,524 - 32,962,025 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,913,920 - 32,929,071 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,869,724 - 32,884,891 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,049,385 - 33,064,860 (+)NCBIUU_Cfam_GSD_1.0
Gucy2d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,761,604 - 47,776,106 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,235,711 - 1,250,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,235,747 - 1,250,294 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY2D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,235,801 - 53,249,467 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,200,570 - 53,250,566 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,602,395 - 55,617,678 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY2D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,391,260 - 7,407,549 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,392,419 - 7,406,305 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,000,751 - 14,016,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gucy2d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,574,968 - 10,588,540 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,574,252 - 10,589,303 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gucy2e
520 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2933
Count of miRNA genes:843
Interacting mature miRNAs:1149
Transcripts:ENSMUST00000021259, ENSMUST00000108664, ENSMUST00000108665, ENSMUST00000155457
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse

Markers in Region
Gucy2e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371169,049,021 - 69,049,581UniSTSGRCm37
Celera1176,188,603 - 76,189,163UniSTS
Cytogenetic Map11B3UniSTS
cM Map1137.0UniSTS
cM Map1137.0UniSTS
Gucy2e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,235,519 - 69,236,079UniSTSGRCm38
MGSCv371169,049,021 - 69,049,581UniSTSGRCm37
Celera1176,188,603 - 76,189,163UniSTS
Cytogenetic Map11B3UniSTS
cM Map1137.0UniSTS
Gucy2e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B3UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000021259   ⟹   ENSMUSP00000021259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,108,943 - 69,127,848 (-)Ensembl
GRCm38.p6 Ensembl1169,218,117 - 69,237,022 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108664   ⟹   ENSMUSP00000104304
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,111,984 - 69,127,862 (-)Ensembl
GRCm38.p6 Ensembl1169,221,158 - 69,237,036 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108665   ⟹   ENSMUSP00000104305
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,108,946 - 69,127,848 (-)Ensembl
GRCm38.p6 Ensembl1169,218,120 - 69,237,022 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155457
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,117,461 - 69,127,848 (-)Ensembl
GRCm38.p6 Ensembl1169,226,635 - 69,237,022 (-)Ensembl
RefSeq Acc Id: NM_008192   ⟹   NP_032218
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,108,943 - 69,127,848 (-)NCBI
GRCm381169,218,117 - 69,237,022 (-)NCBI
MGSCv371169,031,619 - 69,050,524 (-)RGD
Celera1176,171,185 - 76,190,106 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532244   ⟹   XP_006532307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,108,943 - 69,128,082 (-)NCBI
GRCm381169,218,117 - 69,237,258 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156339   ⟹   XP_036012232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,108,943 - 69,128,083 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032218   ⟸   NM_008192
- Peptide Label: precursor
- UniProtKB: B1ASX7 (UniProtKB/Swiss-Prot),   P52785 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532307   ⟸   XM_006532244
- Peptide Label: isoform X2
- UniProtKB: B1ASX7 (UniProtKB/Swiss-Prot),   P52785 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000021259   ⟸   ENSMUST00000021259
RefSeq Acc Id: ENSMUSP00000104304   ⟸   ENSMUST00000108664
RefSeq Acc Id: ENSMUSP00000104305   ⟸   ENSMUST00000108665
RefSeq Acc Id: XP_036012232   ⟸   XM_036156339
- Peptide Label: isoform X1
Protein Domains
Guanylate cyclase   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P52785-F1-model_v2 AlphaFold P52785 1-1108 view protein structure

Promoters
RGD ID:8675156
Promoter ID:EPDNEW_M15609
Type:initiation region
Name:Gucy2e_1
Description:Mus musculus guanylate cyclase 2e , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,237,034 - 69,237,094EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105123 AgrOrtholog
Ensembl Genes ENSMUSG00000020890 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021259 ENTREZGENE
  ENSMUST00000021259.9 UniProtKB/Swiss-Prot
  ENSMUST00000108664 ENTREZGENE
  ENSMUST00000108664.2 UniProtKB/Swiss-Prot
  ENSMUST00000108665.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.1230 UniProtKB/Swiss-Prot
  3.40.50.2300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/Swiss-Prot
  A/G_cyclase_CS UniProtKB/Swiss-Prot
  ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOB_dom_associated UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/Swiss-Prot
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14919 UniProtKB/Swiss-Prot
MGD MGI:105123 ENTREZGENE
NCBI Gene 14919 ENTREZGENE
PANTHER GUANYLYL CYCLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RETINAL GUANYLYL CYCLASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/Swiss-Prot
  HNOBA UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gucy2e PhenoGen
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/Swiss-Prot
  GUANYLATE_CYCLASE_2 UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CYCc UniProtKB/Swiss-Prot
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55073 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1ASX7 ENTREZGENE
  GUC2E_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C8X5_MOUSE UniProtKB/TrEMBL
UniProt Secondary B1ASX7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Gucy2e  guanylate cyclase 2e  BC020186  cDNA sequence BC020186  Data merged from RGD:1610964 737654 PROVISIONAL