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Gene: IREB2 (iron responsive element binding protein 2) Homo sapiens
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Symbol: IREB2
Name: iron responsive element binding protein 2
Description: Exhibits iron-responsive element binding activity. Involved in iron ion homeostasis. Predicted to localize to cytosol and mitochondrion. Implicated in Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACO3; FLJ23381; IRE-BP 2; IRE-BP2; iron regulatory protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; IRP2; IRP2AD; NDCAMA
Orthologs:
Mus musculus (house mouse) : Ireb2 (iron responsive element binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ireb2 (iron responsive element binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ireb2 (iron responsive element binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IREB2 (iron responsive element binding protein 2)
Canis lupus familiaris (dog) : IREB2 (iron responsive element binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ireb2 (iron responsive element binding protein 2)
Sus scrofa (pig) : IREB2 (iron responsive element binding protein 2)
Chlorocebus sabaeus (African green monkey) : IREB2 (iron responsive element binding protein 2)
Heterocephalus glaber (naked mole-rat) : Ireb2 (iron responsive element binding protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1578,437,431 - 78,501,453 (+)EnsemblGRCh38hg38GRCh38
GRCh381578,437,431 - 78,501,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371578,730,518 - 78,793,798 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,517,573 - 76,580,853 (+)NCBINCBI36hg18NCBI36
Build 341576,517,680 - 76,578,522NCBI
Celera1555,667,049 - 55,730,320 (+)NCBI
Cytogenetic Map15q25.1NCBI
HuRef1555,487,914 - 55,551,183 (+)NCBIHuRef
CHM1_11578,849,070 - 78,912,332 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IREB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733858
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.