POLR2G (RNA polymerase II subunit G) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: POLR2G (RNA polymerase II subunit G) Homo sapiens
Analyze
Symbol: POLR2G
Name: RNA polymerase II subunit G
RGD ID: 733856
HGNC Page HGNC:9194
Description: Predicted to enable single-stranded DNA binding activity; single-stranded RNA binding activity; and translation initiation factor binding activity. Involved in transcription by RNA polymerase II. Located in nucleoplasm. Part of RNA polymerase II, core complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DNA directed RNA polymerase II 19 kda polypeptide; DNA-directed RNA polymerase II 19 kDa polypeptide; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; hRPB19; hsRPB7; MGC138367; MGC138369; polymerase (RNA) II (DNA directed) polypeptide G; polymerase (rna) ii (dna directed)polypeptide g; polymerase (RNA) II subunit G; RNA polymerase II 19 kDa subunit; RNA polymerase II seventh subunit; RNA polymerase II subunit B7; RPB19; RPB7
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,761,580 - 62,766,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,761,565 - 62,766,710 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,529,052 - 62,534,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,285,591 - 62,290,757 (+)NCBINCBI36Build 36hg18NCBI36
Build 341162,285,590 - 62,290,757NCBI
Celera1159,857,593 - 59,862,769 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,857,889 - 58,863,065 (+)NCBIHuRef
CHM1_11162,412,016 - 62,417,192 (+)NCBICHM1_1
T2T-CHM13v2.01162,750,899 - 62,756,030 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
2. TFIIB-related factors in RNA polymerase I transcription. Knutson BA and Hahn S, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):265-73. doi: 10.1016/j.bbagrm.2012.08.003. Epub 2012 Aug 30.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1559613   PMID:1939271   PMID:2190099   PMID:2449431   PMID:7579693   PMID:7638159   PMID:7853496   PMID:8637904   PMID:8676484   PMID:8800208   PMID:8849451   PMID:8876177  
PMID:8910388   PMID:8934526   PMID:8946909   PMID:9054383   PMID:9121429   PMID:9184228   PMID:9201987   PMID:9256063   PMID:9311822   PMID:9315662   PMID:9334327   PMID:9405375  
PMID:9409616   PMID:9488465   PMID:9491887   PMID:9512541   PMID:9528765   PMID:9570510   PMID:9651670   PMID:9696809   PMID:9704926   PMID:9765201   PMID:9790902   PMID:9852112  
PMID:9874563   PMID:10066804   PMID:10069959   PMID:10329125   PMID:10359081   PMID:10364292   PMID:10373521   PMID:10393184   PMID:10438593   PMID:10536359   PMID:10545121   PMID:10567706  
PMID:10617616   PMID:10698937   PMID:10704353   PMID:10725406   PMID:10757782   PMID:10777215   PMID:10784442   PMID:10866664   PMID:10931842   PMID:10958691   PMID:11080476   PMID:11112772  
PMID:11547919   PMID:11809800   PMID:12049628   PMID:12052871   PMID:12089333   PMID:12114499   PMID:12126615   PMID:12221105   PMID:12226669   PMID:12379213   PMID:12477932   PMID:12634356  
PMID:12642036   PMID:12676794   PMID:12775419   PMID:12887902   PMID:12912922   PMID:14569024   PMID:14667819   PMID:15175163   PMID:15282305   PMID:15489334   PMID:16282592   PMID:16289656  
PMID:16327806   PMID:16838299   PMID:16957778   PMID:17168834   PMID:17643375   PMID:17661632   PMID:17848138   PMID:18218627   PMID:18562274   PMID:18991615   PMID:19240132   PMID:19526283  
PMID:19615732   PMID:20133760   PMID:20227660   PMID:20471948   PMID:21360054   PMID:21729782   PMID:21873635   PMID:21972559   PMID:21988832   PMID:22211660   PMID:22229121   PMID:22422068  
PMID:22567366   PMID:22939629   PMID:22990118   PMID:23028129   PMID:23073835   PMID:23087374   PMID:23273982   PMID:23274668   PMID:23827503   PMID:24217245   PMID:24330569   PMID:24359561  
PMID:24457600   PMID:24550385   PMID:24981860   PMID:25544563   PMID:25732088   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26673895   PMID:27880917   PMID:28514442   PMID:28515276  
PMID:28700943   PMID:28846114   PMID:29053956   PMID:29150431   PMID:29229926   PMID:29395067   PMID:29449217   PMID:29478914   PMID:29509190   PMID:30389953   PMID:31048545   PMID:31452512  
PMID:32296183   PMID:32355176   PMID:32416067   PMID:32460013   PMID:32985767   PMID:33961781   PMID:34108663   PMID:34244565   PMID:34373451   PMID:35256949   PMID:35271311   PMID:35831314  
PMID:37499664   PMID:37682711   PMID:37866880  


Genomics

Comparative Map Data
POLR2G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,761,580 - 62,766,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,761,565 - 62,766,710 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,529,052 - 62,534,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,285,591 - 62,290,757 (+)NCBINCBI36Build 36hg18NCBI36
Build 341162,285,590 - 62,290,757NCBI
Celera1159,857,593 - 59,862,769 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,857,889 - 58,863,065 (+)NCBIHuRef
CHM1_11162,412,016 - 62,417,192 (+)NCBICHM1_1
T2T-CHM13v2.01162,750,899 - 62,756,030 (+)NCBIT2T-CHM13v2.0
Polr2g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,770,493 - 8,775,921 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,770,491 - 8,775,941 (-)EnsemblGRCm39 Ensembl
GRCm38198,793,129 - 8,798,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,793,127 - 8,798,577 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,867,619 - 8,873,047 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,860,174 - 8,865,602 (-)NCBIMGSCv36mm8
Celera198,553,021 - 8,558,449 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.62NCBI
Polr2g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,118,278 - 215,125,389 (-)NCBIGRCr8
mRatBN7.21205,689,160 - 205,692,537 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,689,160 - 205,692,686 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,097,574 - 214,100,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,132,707 - 221,136,084 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,825,410 - 213,828,787 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,991,250 - 224,998,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,991,222 - 224,994,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,929,423 - 231,936,528 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,462,321 - 211,465,698 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,620,752 - 211,627,860 (-)NCBI
Celera1203,202,089 - 203,205,466 (-)NCBICelera
Cytogenetic Map1q43NCBI
Polr2g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599464,879 - 471,976 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599469,233 - 471,761 (-)NCBIChiLan1.0ChiLan1.0
POLR2G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,986,513 - 63,991,720 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,029,219 - 65,034,411 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,116,833 - 58,122,031 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,470,866 - 61,476,073 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,470,866 - 61,476,073 (+)Ensemblpanpan1.1panPan2
POLR2G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,916,431 - 53,919,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,916,435 - 53,919,549 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,522,261 - 52,530,211 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,968,916 - 54,976,918 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,966,549 - 54,972,077 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,065,288 - 54,073,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,639,765 - 53,647,770 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,436,033 - 54,444,050 (-)NCBIUU_Cfam_GSD_1.0
Polr2g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,409,272 - 10,414,410 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581522,950 - 528,933 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581523,018 - 528,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR2G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,004,390 - 9,017,779 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,004,388 - 9,008,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,349,630 - 8,353,856 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR2G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,140,897 - 11,150,879 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,140,867 - 11,150,882 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,483,625 - 108,488,373 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr2g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,228,602 - 1,230,943 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,228,590 - 1,230,943 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q12.3(chr11:62433886-63096003)x3 copy number gain See cases [RCV000053620] Chr11:62433886..63096003 [GRCh38]
Chr11:62201358..62863475 [GRCh37]
Chr11:61957934..62620051 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh38/hg38 11q12.3(chr11:62452571-62862781)x3 copy number gain See cases [RCV000053621] Chr11:62452571..62862781 [GRCh38]
Chr11:62220043..62630253 [GRCh37]
Chr11:61976619..62386829 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh38/hg38 11q12.3(chr11:62562836-62840570)x3 copy number gain See cases [RCV000134807] Chr11:62562836..62840570 [GRCh38]
Chr11:62330308..62608042 [GRCh37]
Chr11:62086884..62364618 [NCBI36]
Chr11:11q12.3		 uncertain significance
GRCh38/hg38 11q12.3(chr11:62249520-62946093)x3 copy number gain See cases [RCV000138411] Chr11:62249520..62946093 [GRCh38]
Chr11:62016992..62713565 [GRCh37]
Chr11:61773568..62470141 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh37/hg19 11q12.3(chr11:61840997-62987330)x1 copy number loss See cases [RCV000448355] Chr11:61840997..62987330 [GRCh37]
Chr11:11q12.3		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q12.3(chr11:62314663-62788240)x3 copy number gain not provided [RCV000849841] Chr11:62314663..62788240 [GRCh37]
Chr11:11q12.3		 uncertain significance
GRCh37/hg19 11q12.3(chr11:62487052-62788240)x3 copy number gain not provided [RCV000846292] Chr11:62487052..62788240 [GRCh37]
Chr11:11q12.3		 uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
NC_000011.9:g.(?_58916346)_(64972349_?)dup duplication Leukocyte adhesion deficiency 3 [RCV003113394]|not provided [RCV003113393] Chr11:58916346..64972349 [GRCh37]
Chr11:11q12.1-13.1		 uncertain significance|no classifications from unflagged records
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3 copy number gain not specified [RCV003986918] Chr11:50398499..63924462 [GRCh37]
Chr11:11p11.12-q13.1		 likely pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2276
Count of miRNA genes:760
Interacting mature miRNAs:857
Transcripts:ENST00000301788, ENST00000524819, ENST00000525455, ENST00000526368, ENST00000527435, ENST00000531944, ENST00000531996, ENST00000533442
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-30229  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,534,003 - 62,534,152UniSTSGRCh37
Build 361162,290,579 - 62,290,728RGDNCBI36
Celera1159,862,585 - 59,862,734RGD
Cytogenetic Map11q13.1UniSTS
HuRef1158,862,881 - 58,863,030UniSTS
Stanford-G3 RH Map112711.0UniSTS
GeneMap99-GB4 RH Map11236.75UniSTS
Whitehead-RH Map11288.2UniSTS
NCBI RH Map11563.0UniSTS
GeneMap99-G3 RH Map112711.0UniSTS
A004H14  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,534,005 - 62,534,177UniSTSGRCh37
Build 361162,290,581 - 62,290,753RGDNCBI36
Celera1159,862,587 - 59,862,759RGD
Cytogenetic Map11q13.1UniSTS
HuRef1158,862,883 - 58,863,055UniSTS
GeneMap99-GB4 RH Map11230.54UniSTS
NCBI RH Map11563.0UniSTS
SGC31630  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,533,979 - 62,534,153UniSTSGRCh37
Build 361162,290,555 - 62,290,729RGDNCBI36
Celera1159,862,561 - 59,862,735RGD
Cytogenetic Map11q13.1UniSTS
HuRef1158,862,857 - 58,863,031UniSTS
GeneMap99-GB4 RH Map11236.75UniSTS
Whitehead-RH Map11287.3UniSTS
NCBI RH Map11563.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2438 2848 1692 590 1927 432 4328 2061 3694 413 1457 1612 175 1 1204 2759 6 1
Low 1 143 34 34 24 33 29 136 40 6 3 1 29 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000301788   ⟹   ENSP00000301788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,580 - 62,766,710 (+)Ensembl
RefSeq Acc Id: ENST00000524819   ⟹   ENSP00000431624
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,583 - 62,766,695 (+)Ensembl
RefSeq Acc Id: ENST00000525455   ⟹   ENSP00000433529
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,580 - 62,766,673 (+)Ensembl
RefSeq Acc Id: ENST00000526368
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,762,754 - 62,766,707 (+)Ensembl
RefSeq Acc Id: ENST00000527435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,637 - 62,766,710 (+)Ensembl
RefSeq Acc Id: ENST00000531944   ⟹   ENSP00000433877
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,617 - 62,766,710 (+)Ensembl
RefSeq Acc Id: ENST00000531996   ⟹   ENSP00000435669
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,795 - 62,765,724 (+)Ensembl
RefSeq Acc Id: ENST00000533442   ⟹   ENSP00000432198
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,761,565 - 62,765,356 (+)Ensembl
RefSeq Acc Id: NM_002696   ⟹   NP_002687
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,761,580 - 62,766,710 (+)NCBI
GRCh371162,529,011 - 62,534,187 (+)ENTREZGENE
Build 361162,285,591 - 62,290,757 (+)NCBI Archive
HuRef1158,857,889 - 58,863,065 (+)ENTREZGENE
CHM1_11162,412,016 - 62,417,192 (+)NCBI
T2T-CHM13v2.01162,750,899 - 62,756,030 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_002687   ⟸   NM_002696
- UniProtKB: P52433 (UniProtKB/Swiss-Prot),   B2R5C0 (UniProtKB/Swiss-Prot),   Q2M1Z4 (UniProtKB/Swiss-Prot),   P62487 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000435669   ⟸   ENST00000531996
RefSeq Acc Id: ENSP00000433877   ⟸   ENST00000531944
RefSeq Acc Id: ENSP00000432198   ⟸   ENST00000533442
RefSeq Acc Id: ENSP00000431624   ⟸   ENST00000524819
RefSeq Acc Id: ENSP00000433529   ⟸   ENST00000525455
RefSeq Acc Id: ENSP00000301788   ⟸   ENST00000301788

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62487-F1-model_v2 AlphaFold P62487 1-172 view protein structure

Promoters
RGD ID:6789252
Promoter ID:HG_KWN:13133
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_002696,   UC001NVB.1,   UC009YOE.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361162,285,449 - 62,285,949 (+)MPROMDB
RGD ID:6852334
Promoter ID:EP73974
Type:initiation region
Name:HS_POLR2G
Description:Polymerase (RNA) II (DNA directed) polypeptide G.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 361162,285,628 - 62,285,688EPD
RGD ID:7220721
Promoter ID:EPDNEW_H16106
Type:initiation region
Name:POLR2G_1
Description:RNA polymerase II subunit G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,761,580 - 62,761,640EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9194 AgrOrtholog
COSMIC POLR2G COSMIC
Ensembl Genes ENSG00000168002 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000301788 ENTREZGENE
  ENST00000301788.12 UniProtKB/Swiss-Prot
  ENST00000524819.5 UniProtKB/TrEMBL
  ENST00000525455.5 UniProtKB/TrEMBL
  ENST00000531944.5 UniProtKB/TrEMBL
  ENST00000531996.5 UniProtKB/TrEMBL
  ENST00000533442.5 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/Swiss-Prot
  3.30.1490.120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000168002 GTEx
HGNC ID HGNC:9194 ENTREZGENE
Human Proteome Map POLR2G Human Proteome Map
InterPro NA-bd_OB-fold UniProtKB/Swiss-Prot
  RNA_pol_Rpb7-like_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rpb7-like UniProtKB/Swiss-Prot
  Rpb7-like_N UniProtKB/Swiss-Prot
  S1_domain UniProtKB/Swiss-Prot
KEGG Report hsa:5436 UniProtKB/Swiss-Prot
NCBI Gene 5436 ENTREZGENE
OMIM 602013 OMIM
PANTHER DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 UniProtKB/Swiss-Prot
  PTHR12709 UniProtKB/Swiss-Prot
Pfam PF00575 UniProtKB/Swiss-Prot
  SHS2_Rpb7-N UniProtKB/Swiss-Prot
PharmGKB PA33514 PharmGKB
SMART SM00316 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50249 UniProtKB/Swiss-Prot
  SSF88798 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2R5C0 ENTREZGENE
  E9PIU7_HUMAN UniProtKB/TrEMBL
  E9PKH3_HUMAN UniProtKB/TrEMBL
  E9PS03_HUMAN UniProtKB/TrEMBL
  H0YEE4_HUMAN UniProtKB/TrEMBL
  P52433 ENTREZGENE
  P62487 ENTREZGENE
  Q2M1Z4 ENTREZGENE
  RPB7_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B2R5C0 UniProtKB/Swiss-Prot
  P52433 UniProtKB/Swiss-Prot
  Q2M1Z4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-19 POLR2G  RNA polymerase II subunit G  POLR2G  polymerase (RNA) II subunit G  Symbol and/or name change 5135510 APPROVED
2016-03-07 POLR2G  polymerase (RNA) II subunit G  POLR2G  polymerase (RNA) II (DNA directed) polypeptide G  Symbol and/or name change 5135510 APPROVED