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Gene: Serpinb7 (serine (or cysteine) peptidase inhibitor, clade B, member 7) Mus musculus
Symbol: Serpinb7
Name: serine (or cysteine) peptidase inhibitor, clade B, member 7
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including positive regulation of collagen biosynthetic process; positive regulation of cytokine production; and positive regulation of glomerular mesangial cell proliferation. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and familial encephalopathy with neuroserpin inclusion bodies. Is expressed in olfactory epithelium. Orthologous to human SERPINB7 (serpin family B member 7); INTERACTS WITH Benzo[k]fluoranthene; 17beta-estradiol (ortholog); aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4631416M05Rik; megsin; ovalbumin; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7; serine (or cysteine) proteinase inhibitor, clade B, member 7; serpin B7
Homo sapiens (human) : SERPINB7 (serpin family B member 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpinb7 (serpin family B member 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinb7 (serpin family B member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINB7 (serpin family B member 7)
Canis lupus familiaris (dog) : SERPINB7 (serpin family B member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinb7 (serpin family B member 7)
Sus scrofa (pig) : SERPINB7 (serpin family B member 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1107,399,655 - 107,452,689 (+)Ensembl
GRCm381107,422,689 - 107,452,689 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371109,319,266 - 109,349,266 (+)NCBIGRCm37mm9NCBIm37
MGSCv361109,250,236 - 109,280,235 (+)NCBImm8
Celera1110,260,443 - 110,291,388 (+)NCBICelera
Cytogenetic Map1 E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Serpinb7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733832
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.