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Gene: NFIB (nuclear factor I B) Homo sapiens
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Symbol: NFIB
Name: nuclear factor I B
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription corepressor activity. Involved in brain development; negative regulation of DNA binding activity; and regulation of transcription by RNA polymerase II. Localizes to the fibrillar center and nucleoplasm; PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CCAAT-box-binding transcription factor; CTF; HMGIC/NFIB; MACID; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3; nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I/B; TGGCA-binding protein
Orthologs:
Mus musculus (house mouse) : Nfib (nuclear factor I/B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfib (nuclear factor I/B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfib (nuclear factor I B)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIB (nuclear factor I B)
Canis lupus familiaris (dog) : NFIB (nuclear factor I B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfib (nuclear factor I B)
Sus scrofa (pig) : NFIB (nuclear factor I B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38914,081,843 - 14,532,077 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37914,081,842 - 14,398,982 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36914,071,847 - 14,303,945 (-)NCBINCBI36hg18NCBI36
Build 34914,077,372 - 14,303,719NCBI
Celera914,015,384 - 14,332,471 (-)NCBI
Cytogenetic Map9p23-p22.3NCBI
HuRef914,045,221 - 14,362,372 (-)NCBIHuRef
CHM1_1914,081,962 - 14,399,030 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NFIB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733820
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.