Gene: Cacna1e (calcium channel, voltage-dependent, R type, alpha 1E subunit) Mus musculus
Symbol: Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Description: This gene encodes an integral membrane protein that belongs to the calcium channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A430040I15; alpha1E; BII; brain calcium channel II; Cach6; Cacnl1a6; calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; Cav2.3; Cchra1; voltage-dependent R-type calcium channel subunit alpha-1E; voltage-gated calcium channel subunit alpha Cav2.3
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381154,390,806 - 154,884,786 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371156,239,649 - 156,573,050 (-)NCBIGRCm37mm9NCBIm37
MGSCv361156,158,170 - 156,488,574 (-)NCBImm8
Celera1156,824,777 - 157,160,713 (-)NCBICelera
Cytogenetic Map1 G3NCBI
cM Map166.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Cacna1e
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733703
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-02-05
Status: ACTIVE