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Gene: Cacna1e (calcium channel, voltage-dependent, R type, alpha 1E subunit) Mus musculus
Symbol: Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Description: Exhibits protein N-terminus binding activity and voltage-gated calcium channel activity. Involved in several processes, including behavioral fear response; regulation of peptide hormone secretion; and visual learning. Localizes to the integral component of postsynaptic membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Is expressed in central nervous system; dorsal root ganglion; heart; and lower jaw molar. Orthologous to human CACNA1E (calcium voltage-gated channel subunit alpha1 E).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A430040I15; alpha1E; BII; brain calcium channel II; Cach6; Cacnl1a6; calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; Cav2.3; Cchra1; voltage-dependent R-type calcium channel subunit alpha-1E; voltage-gated calcium channel subunit alpha Cav2.3
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381154,390,806 - 154,884,785 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371156,239,649 - 156,573,050 (-)NCBIGRCm37mm9NCBIm37
MGSCv361156,158,170 - 156,488,574 (-)NCBImm8
Celera1156,824,777 - 157,160,713 (-)NCBICelera
Cytogenetic Map1 G3NCBI
cM Map166.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cacna1e
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733703
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.