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Gene: Gata3 (GATA binding protein 3) Mus musculus
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Symbol: Gata3
Name: GATA binding protein 3
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; interleukin-2 receptor binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; regulation of histone modification; and regulation of kidney development. Localizes to the nucleus. Used to study hypoparathyroidism-deafness-renal disease syndrome. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Is expressed in several structures, including branchial arch; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human GATA3 (GATA binding protein 3); PARTICIPATES IN interleukin-27 signaling pathway; Notch signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,4-benzoquinone; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gata-3; GATA-binding factor 3; GATA-binding protein 3; jal; trans-acting T-cell-specific transcription factor GATA-3
Orthologs:
Homo sapiens (human) : GATA3 (GATA binding protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gata3 (GATA binding protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata3 (GATA binding protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA3 (GATA binding protein 3)
Canis lupus familiaris (dog) : GATA3 (GATA binding protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata3 (GATA binding protein 3)
Sus scrofa (pig) : GATA3 (GATA binding protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3829,857,078 - 9,887,953 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3729,778,705 - 9,800,227 (-)NCBIGRCm37mm9NCBIm37
MGSCv3629,774,931 - 9,795,629 (-)NCBImm8
Celera29,794,542 - 9,816,062 (-)NCBICelera
Cytogenetic Map2 A1NCBI
cM Map26.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gata3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733639
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.