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Gene: Gata3 (GATA binding protein 3) Mus musculus
Symbol: Gata3
Name: GATA binding protein 3
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; interleukin-2 receptor binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; regulation of histone modification; and regulation of kidney development. Localizes to the nucleus. Used to study hypoparathyroidism-deafness-renal disease syndrome. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Is expressed in several structures, including branchial arch; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human GATA3 (GATA binding protein 3); PARTICIPATES IN interleukin-27 signaling pathway; Notch signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,4-benzoquinone; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gata-3; GATA-binding factor 3; GATA-binding protein 3; jal; trans-acting T-cell-specific transcription factor GATA-3
Homo sapiens (human) : GATA3 (GATA binding protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gata3 (GATA binding protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata3 (GATA binding protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA3 (GATA binding protein 3)
Canis lupus familiaris (dog) : GATA3 (GATA binding protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata3 (GATA binding protein 3)
Sus scrofa (pig) : GATA3 (GATA binding protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3829,857,078 - 9,887,953 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3729,778,705 - 9,800,227 (-)NCBIGRCm37mm9NCBIm37
MGSCv3629,774,931 - 9,795,629 (-)NCBImm8
Celera29,794,542 - 9,816,062 (-)NCBICelera
Cytogenetic Map2 A1NCBI
cM Map26.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gata3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733639
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.