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Gene: CLK3 (CDC like kinase 3) Homo sapiens
Symbol: CLK3
Name: CDC like kinase 3
Description: This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC-like kinase 3; dual specificity protein kinase CLK3; FLJ22858; PHCLK3; PHCLK3/152
Mus musculus (house mouse) : Clk3 (CDC-like kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clk3 (CDC-like kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clk3 (CDC like kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CLK3 (CDC like kinase 3)
Canis lupus familiaris (dog) : CLK3 (CDC like kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clk3 (CDC like kinase 3)
Sus scrofa (pig) : CLK3 (CDC like kinase 3)
more info ...
Related Pseudogenes: CLK3P1   CLK3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381574,598,476 - 74,645,418 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371574,898,327 - 74,922,542 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,687,766 - 72,709,511 (+)NCBINCBI36hg18NCBI36
Build 341572,687,765 - 72,709,511NCBI
Celera1551,850,648 - 51,872,477 (+)NCBI
Cytogenetic Map15q24.1NCBI
HuRef1551,698,874 - 51,720,703 (+)NCBIHuRef
CHM1_11575,019,166 - 75,040,995 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733625
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.