Ptpn2 (protein tyrosine phosphatase, non-receptor type 2) - Rat Genome Database
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Gene: Ptpn2 (protein tyrosine phosphatase, non-receptor type 2) Mus musculus
Analyze
Symbol: Ptpn2
Name: protein tyrosine phosphatase, non-receptor type 2
RGD ID: 733576
MGI Page MGI
Description: Is expressed in several structures, including genitourinary system; heart; hemolymphoid system gland; lower jaw; and midbrain. Orthologous to human PTPN2 (protein tyrosine phosphatase non-receptor type 2); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325124; MPTP; protein-tyrosine phosphatase PTP-2; Pt; Ptpt; T cell protein-tyrosine phosphatase; TC-P; TC-PTP; tyrosine-protein phosphatase non-receptor type 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391867,798,571 - 67,857,697 (-)NCBIGRCm39mm39
GRCm39 Ensembl1867,798,581 - 67,857,665 (-)Ensembl
GRCm381867,665,501 - 67,724,632 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,665,511 - 67,724,595 (-)EnsemblGRCm38mm10GRCm38
MGSCv371867,825,155 - 67,884,275 (-)NCBIGRCm37mm9NCBIm37
MGSCv361867,790,882 - 67,849,946 (-)NCBImm8
Celera1868,948,003 - 69,006,677 (-)NCBICelera
Cytogenetic Map18E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell differentiation  (IMP)
dephosphorylation  (IEA)
erythrocyte differentiation  (IMP)
glucose homeostasis  (IMP)
insulin receptor signaling pathway  (IMP)
negative regulation of cell population proliferation  (ISO)
negative regulation of chemotaxis  (IMP)
negative regulation of epidermal growth factor receptor signaling pathway  (ISO)
negative regulation of ERK1 and ERK2 cascade  (IMP)
negative regulation of inflammatory response  (IMP)
negative regulation of insulin receptor signaling pathway  (IMP)
negative regulation of interferon-gamma-mediated signaling pathway  (IMP)
negative regulation of interleukin-2-mediated signaling pathway  (IMP,ISO)
negative regulation of interleukin-4-mediated signaling pathway  (IMP,ISO)
negative regulation of interleukin-6-mediated signaling pathway  (IMP,ISO)
negative regulation of lipid storage  (IMP)
negative regulation of macrophage colony-stimulating factor signaling pathway  (IMP)
negative regulation of macrophage differentiation  (IMP)
negative regulation of platelet-derived growth factor receptor-beta signaling pathway  (IMP)
negative regulation of positive thymic T cell selection  (IMP)
negative regulation of protein tyrosine kinase activity  (IMP)
negative regulation of T cell receptor signaling pathway  (IMP)
negative regulation of transcription by RNA polymerase II  (IPI)
negative regulation of tumor necrosis factor-mediated signaling pathway  (IMP)
negative regulation of type I interferon-mediated signaling pathway  (IMP,ISO)
negative regulation of tyrosine phosphorylation of STAT protein  (IMP,ISO)
peptidyl-tyrosine dephosphorylation  (IMP,ISO)
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (IMP)
positive regulation of gluconeogenesis  (IMP)
positive regulation of PERK-mediated unfolded protein response  (IMP)
protein dephosphorylation  (IDA,IGI,IMP)
regulation of hepatocyte growth factor receptor signaling pathway  (ISO)
T cell differentiation  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell number  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal bone marrow cell number  (IAGP)
abnormal bone structure  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal homeostasis  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal long bone epiphyseal ossification zone morphology  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal lymph node morphology  (IAGP)
abnormal negative T cell selection  (IAGP)
abnormal ossification involved in bone maturation  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal pilomotor reflex  (IAGP)
abnormal positive T cell selection  (IAGP)
abnormal respiratory quotient  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
abnormal thymus involution  (IAGP)
anemia  (IAGP)
decreased B cell number  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone trabecula number  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased diameter of femur  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased follicular B cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased immature B cell number  (IAGP)
decreased lean body mass  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased T cell number  (IAGP)
decreased thymocyte number  (IAGP)
decreased total body fat amount  (IAGP)
decreased trabecular bone volume  (IAGP)
diarrhea  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
hunched posture  (IAGP)
hypoactivity  (IAGP)
increased adiponectin level  (IAGP)
increased B cell number  (IAGP)
increased bone mineral density  (IAGP)
increased bone resorption  (IAGP)
increased bone trabecula number  (IAGP)
increased carbon dioxide production  (IAGP)
increased circulating osteocalcin level  (IAGP)
increased energy expenditure  (IAGP)
increased hemoglobin content  (IEA)
increased inflammatory response  (IAGP)
increased insulin sensitivity  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-12 secretion  (IAGP)
increased macrophage cell number  (IAGP)
increased mature B cell number  (IAGP)
increased mean corpuscular hemoglobin  (IEA)
increased oxygen consumption  (IAGP)
increased pre-B cell number  (IAGP)
increased spleen red pulp amount  (IAGP)
increased splenocyte number  (IAGP)
increased total body fat amount  (IAGP)
increased trabecular bone volume  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
lymph node hyperplasia  (IAGP)
narrow eye opening  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
short femur  (IAGP)
spleen hyperplasia  (IAGP)
thymus atrophy  (IAGP)
References

Additional References at PubMed
PMID:1283199   PMID:1731319   PMID:1733852   PMID:8267598   PMID:8875997   PMID:9271584   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11907034   PMID:11909529  
PMID:12138178   PMID:12171910   PMID:12477932   PMID:12520002   PMID:12612081   PMID:12847239   PMID:12904583   PMID:14600148   PMID:14610273   PMID:14726372   PMID:14744882   PMID:14966296  
PMID:15489334   PMID:15592458   PMID:15632081   PMID:15696169   PMID:16141072   PMID:16141073   PMID:16198645   PMID:16602821   PMID:16705167   PMID:16971512   PMID:17210636   PMID:17234741  
PMID:17967808   PMID:18775329   PMID:18799693   PMID:18819921   PMID:18948751   PMID:19474293   PMID:19727691   PMID:19755676   PMID:19930043   PMID:20059965   PMID:20111595   PMID:20421975  
PMID:20473312   PMID:20484139   PMID:20924113   PMID:20940300   PMID:21216966   PMID:21267068   PMID:21435452   PMID:21677750   PMID:21968903   PMID:22000926   PMID:22080863   PMID:22124607  
PMID:22252315   PMID:22590589   PMID:23135963   PMID:23166300   PMID:24040033   PMID:24442435   PMID:24445916   PMID:24954415   PMID:24997008   PMID:25338551   PMID:25406309   PMID:25492475  
PMID:25594176   PMID:26026268   PMID:26410627   PMID:26496610   PMID:26815406   PMID:27115526   PMID:27611995   PMID:27626668   PMID:27658548   PMID:27841348   PMID:28287113   PMID:28322331  
PMID:28723893   PMID:28768176   PMID:28798028   PMID:29233935   PMID:29444435   PMID:29587266   PMID:29712668   PMID:29797458   PMID:29955047   PMID:30230471   PMID:30454647   PMID:30620725  
PMID:30936146   PMID:30955247   PMID:30971695   PMID:31373168   PMID:31509751   PMID:31527834   PMID:31803974   PMID:32325033   PMID:32726622   PMID:32973765   PMID:33330862  


Genomics

Comparative Map Data
Ptpn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391867,798,571 - 67,857,697 (-)NCBIGRCm39mm39
GRCm39 Ensembl1867,798,581 - 67,857,665 (-)Ensembl
GRCm381867,665,501 - 67,724,632 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,665,511 - 67,724,595 (-)EnsemblGRCm38mm10GRCm38
MGSCv371867,825,155 - 67,884,275 (-)NCBIGRCm37mm9NCBIm37
MGSCv361867,790,882 - 67,849,946 (-)NCBImm8
Celera1868,948,003 - 69,006,677 (-)NCBICelera
Cytogenetic Map18E1NCBI
PTPN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1812,785,478 - 12,929,643 (-)EnsemblGRCh38hg38GRCh38
GRCh381812,785,478 - 12,884,351 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371812,785,477 - 12,884,236 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361812,775,480 - 12,874,334 (-)NCBINCBI36hg18NCBI36
Build 341812,783,247 - 12,874,334NCBI
Celera1812,668,269 - 12,766,833 (-)NCBI
Cytogenetic Map18p11.21NCBI
HuRef1812,739,218 - 12,838,298 (-)NCBIHuRef
CHM1_11812,784,828 - 12,883,350 (-)NCBICHM1_1
Ptpn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21861,229,012 - 61,294,662 (-)NCBI
Rnor_6.0 Ensembl1863,415,306 - 63,488,027 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01863,415,298 - 63,489,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01862,600,260 - 62,671,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41864,205,920 - 64,271,288 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11864,279,120 - 64,344,489 (-)NCBI
Celera1859,335,151 - 59,399,819 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Ptpn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955402771,410 - 846,671 (+)NCBIChiLan1.0ChiLan1.0
PTPN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11816,562,044 - 16,659,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1816,562,052 - 16,659,570 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0181,440,837 - 1,538,501 (+)NCBIMhudiblu_PPA_v0panPan3
PTPN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl778,160,589 - 78,252,719 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1778,160,564 - 78,252,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ptpn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366262,390,004 - 2,472,039 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl696,770,251 - 96,847,133 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1696,769,862 - 96,847,136 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2690,126,609 - 90,272,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11871,302,082 - 71,400,201 (-)NCBI
ChlSab1.1 Ensembl1871,310,577 - 71,345,960 (-)Ensembl
Ptpn2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477019,808,400 - 19,877,494 (-)NCBI

Position Markers
AI325124  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18E1UniSTS
UniSTS:237830  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381867,671,334 - 67,671,634UniSTSGRCm38
MGSCv371867,830,988 - 67,831,288UniSTSGRCm37
Celera1868,953,843 - 68,954,143UniSTS
Cytogenetic Map18E1UniSTS
UniSTS:237831  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381867,672,021 - 67,672,264UniSTSGRCm38
MGSCv371867,831,675 - 67,831,918UniSTSGRCm37
Celera1868,954,530 - 68,954,773UniSTS
Cytogenetic Map18E1UniSTS
Ptpn2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18E1UniSTS
cM Map1840.06UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182476282478296340Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183552556069525779Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183615795070158108Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183807349772073497Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183807349772073497Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183807349772073497Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183807349772073497Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183897060572970721Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183948686184620653Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184317804877178271Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184499753768645706Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184629021680290216Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184674183280741971Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184674183280741971Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185091908584919240Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185091908584919240Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185153522985535397Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185153522985535397Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185267220586672345Mouse
1302050Radpf4_mradiation pulmonary fibrosis 4 (mouse)Not determined185283308468645706Mouse
4142443Pgis1_mproteoglycan induced spondylitis 1 (mouse)Not determined185315795076826598Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185484280185496018Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185630000090300000Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185630000090300000Mouse
12880428V125Dq14_mvitamin D active form serum level QTL 14 (mouse)185730000090702639Mouse
1301353Lbw6_mlupus NZB x NZW 6 (mouse)Not determined185742926790702639Mouse
4141132Eae18_mexperimental allergic encephalomyelitis susceptibility 18 (mouse)Not determined5745748782586603Mouse
4140971Mbmq1_mmale body mass QTL 1 (mouse)Not determined5785721090702639Mouse
12910791Pwgrq8_mpre-weaning growth rate QTL 8 (mouse)185788832769216071Mouse
11039492Ltpr8a_mLeishmania tropica response 8a (mouse)185904702190702639Mouse
11039495Ltpr8c_mLeishmania tropica response 8c (mouse)185904702190702639Mouse
11049564Lmr29_mleishmaniasis resistance 29 (mouse)185904702190702639Mouse
1301103Pgia11_mproteoglycan induced arthritis 11 (mouse)Not determined185982648990702639Mouse
1302109Sluc28_msusceptibility to lung cancer 28 (mouse)Not determined185984762690702639Mouse
38455998Cdtm1_mCD62L+ CD8 TM cells 1 (mouse)186000000080000000Mouse
10412265Par7_mpulmonary adenoma resistance 7 (mouse)Not determined186113937667919240Mouse
4142239Idd21.2_minsulin dependent diabetes susceptibility 21.2 (mouse)Not determined186113937674429343Mouse
1558803W3q16_mweight 3 weeks QTL 16 (mouse)Not determined186113937681448616Mouse
1558782Orgwq9_morgan weight QTL 9 (mouse)Not determined186113937682586603Mouse
11039518Ltpr8_mLeishmania tropica response 8 (mouse)186374183276047170Mouse
12798542Ett1_mexperimentally induced testicular teratoma 1 (mouse)186654107868535397Mouse
1301798Hdlq31_mHDL QTL 31 (mouse)Not determined186712626490702639Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:682
Count of miRNA genes:390
Interacting mature miRNAs:451
Transcripts:ENSMUST00000025420, ENSMUST00000120934, ENSMUST00000122412, ENSMUST00000128169
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA560046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV552728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M80739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M81477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S52655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000025420   ⟹   ENSMUSP00000025420
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1867,665,512 - 67,724,588 (-)Ensembl
RefSeq Acc Id: ENSMUST00000120934   ⟹   ENSMUSP00000113182
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1867,665,511 - 67,724,573 (-)Ensembl
RefSeq Acc Id: ENSMUST00000122412   ⟹   ENSMUSP00000112675
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1867,671,212 - 67,724,595 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128169
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1867,675,818 - 67,690,224 (-)Ensembl
RefSeq Acc Id: NM_001127177   ⟹   NP_001120649
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391867,798,571 - 67,857,691 (-)NCBI
GRCm381867,665,501 - 67,724,621 (-)NCBI
MGSCv371867,825,155 - 67,884,275 (-)RGD
Celera1868,948,003 - 69,006,677 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008977   ⟹   NP_033003
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391867,798,571 - 67,857,691 (-)NCBI
GRCm381867,665,501 - 67,724,621 (-)NCBI
MGSCv371867,825,155 - 67,884,275 (-)RGD
Celera1868,948,003 - 69,006,677 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011246858   ⟹   XP_011245160
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391867,798,571 - 67,857,697 (-)NCBI
GRCm381867,665,501 - 67,724,632 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246859   ⟹   XP_011245161
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391867,798,571 - 67,844,858 (-)NCBI
GRCm381867,665,501 - 67,711,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250364   ⟹   XP_030106224
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391867,798,571 - 67,857,695 (-)NCBI
GRCm381867,665,501 - 67,724,630 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033003   ⟸   NM_008977
- Peptide Label: isoform a
- UniProtKB: Q06180 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120649   ⟸   NM_001127177
- Peptide Label: isoform b
- UniProtKB: Q06180 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011245160   ⟸   XM_011246858
- Peptide Label: isoform X1
- UniProtKB: Q06180 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011245161   ⟸   XM_011246859
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030106224   ⟸   XM_030250364
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000113182   ⟸   ENSMUST00000120934
RefSeq Acc Id: ENSMUSP00000025420   ⟸   ENSMUST00000025420
RefSeq Acc Id: ENSMUSP00000112675   ⟸   ENSMUST00000122412
Promoters
RGD ID:13678082
Promoter ID:EPDNEW_M23190
Type:initiation region
Name:Ptpn2_1
Description:Mus musculus protein tyrosine phosphatase, non-receptor type2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381867,724,590 - 67,724,650EPDNEW
RGD ID:6829488
Promoter ID:MM_KWN:25604
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000120934,   NM_001127177,   NM_008977
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361867,884,066 - 67,885,182 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97806 AgrOrtholog
Ensembl Genes ENSMUSG00000024539 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000025420 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000112675 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000113182 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025420 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000120934 UniProtKB/TrEMBL
  ENSMUST00000122412 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ptpn1/Ptpn2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19255 UniProtKB/Swiss-Prot
MGD MGI:97806 ENTREZGENE
NCBI Gene 19255 ENTREZGENE
Pfam Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptpn2 PhenoGen
PIRSF Tyr-Ptase_nr1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z6W2_MOUSE UniProtKB/TrEMBL
  PTN2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TAP3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3V259 UniProtKB/Swiss-Prot
  Q922E7 UniProtKB/Swiss-Prot