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Gene: Ptpn2 (protein tyrosine phosphatase, non-receptor type 2) Mus musculus
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Symbol: Ptpn2
Name: protein tyrosine phosphatase, non-receptor type 2
Description: Exhibits STAT family protein binding activity and protein tyrosine phosphatase activity. Involved in several processes, including hemopoiesis; negative regulation of signal transduction; and positive regulation of response to endoplasmic reticulum stress. Localizes to the nucleus. Predicted to colocalize with the plasma membrane. Is expressed in several structures, including genitourinary system; heart; hemolymphoid system gland; lower jaw; and midbrain. Orthologous to human PTPN2 (protein tyrosine phosphatase non-receptor type 2); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325124; MPTP; protein-tyrosine phosphatase PTP-2; Ptpt; T cell protein-tyrosine phosphatase; TC-PTP; tyrosine-protein phosphatase non-receptor type 2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1867,665,511 - 67,724,595 (-)Ensembl
GRCm381867,665,501 - 67,724,632 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371867,825,155 - 67,884,275 (-)NCBIGRCm37mm9NCBIm37
MGSCv361867,790,882 - 67,849,946 (-)NCBImm8
Celera1868,948,003 - 69,006,677 (-)NCBICelera
Cytogenetic Map18 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ptpn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733576
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.