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Gene: Btc (betacellulin, epidermal growth factor family member) Mus musculus
Symbol: Btc
Name: betacellulin, epidermal growth factor family member
RGD ID: 733574
Description: Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in negative regulation of apoptotic process and positive regulation of cell population proliferation. Predicted to localize to extracellular space and membrane. Is expressed in lung; reproductive system; and skin. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human BTC (betacellulin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bcn; betacellulin; probetacellulin
Homo sapiens (human) : BTC (betacellulin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Btc (betacellulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Btc (betacellulin)
Pan paniscus (bonobo/pygmy chimpanzee) : BTC (betacellulin)
Canis lupus familiaris (dog) : BTC (betacellulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Btc (betacellulin)
Sus scrofa (pig) : BTC (betacellulin)
Chlorocebus sabaeus (African green monkey) : BTC (betacellulin)
Heterocephalus glaber (naked mole-rat) : Btc (betacellulin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39591,505,120 - 91,550,853 (-)NCBI
GRCm38591,357,261 - 91,402,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl591,357,261 - 91,402,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv37591,786,287 - 91,831,939 (-)NCBIGRCm37mm9NCBIm37
MGSCv36592,432,461 - 92,478,113 (-)NCBImm8
Celera589,495,391 - 89,540,704 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map544.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Btc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733574
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.