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Gene: GGT5 (gamma-glutamyltransferase 5) Homo sapiens
Symbol: GGT5
Name: gamma-glutamyltransferase 5
Description: Exhibits glutathione hydrolase activity; leukotriene-C(4) hydrolase; and peptidyltransferase activity. Involved in carboxylic acid metabolic process; glutathione catabolic process; and proteolysis. Localizes to intrinsic component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp566O011; FLJ92733; gamma-glutamyl cleaving enzyme; gamma-glutamyl transpeptidase-related enzyme; gamma-glutamyl transpeptidase-related protein; gamma-glutamyltransferase-like activity 1; gamma-glutamyltranspeptidase 5; GGL; GGT 5; GGT-REL; GGTLA1; glutathione hydrolase 5; glutathione hydrolase 5 proenzyme; leukotriene-C4 hydrolase
Mus musculus (house mouse) : Ggt5 (gamma-glutamyltransferase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ggt5 (gamma-glutamyltransferase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ggt5 (gamma-glutamyltransferase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GGT5 (gamma-glutamyltransferase 5)
Canis lupus familiaris (dog) : GGT5 (gamma-glutamyltransferase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ggt5 (gamma-glutamyltransferase 5)
Sus scrofa (pig) : GGT5 (gamma-glutamyltransferase 5)
Heterocephalus glaber (naked mole-rat) : Ggt5 (gamma-glutamyltransferase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2224,219,654 - 24,245,142 (-)EnsemblGRCh38hg38GRCh38
GRCh382224,219,654 - 24,245,142 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372224,615,622 - 24,641,317 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,945,622 - 22,971,110 (-)NCBINCBI36hg18NCBI36
Build 342222,940,192 - 22,965,582NCBI
Celera228,416,020 - 8,441,502 (-)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,564,739 - 7,590,237 (-)NCBIHuRef
CHM1_12224,574,371 - 24,599,750 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GGT5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733414
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.