Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CLCN2 (chloride voltage-gated channel 2) Homo sapiens
Analyze
Symbol: CLCN2
Name: chloride voltage-gated channel 2
Description: Exhibits voltage-gated chloride channel activity. Involved in regulation of aldosterone biosynthetic process. Localizes to the plasma membrane. Implicated in idiopathic generalized epilepsy 11 and primary hyperaldosteronism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel 2; chloride channel protein 2; chloride channel, voltage-sensitive 2; CIC-2; clC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; HALD2; LKPAT
Orthologs:
Mus musculus (house mouse) : Clcn2 (chloride channel, voltage-sensitive 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clcn2 (chloride voltage-gated channel 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn2 (chloride voltage-gated channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN2 (chloride voltage-gated channel 2)
Canis lupus familiaris (dog) : CLCN2 (chloride voltage-gated channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn2 (chloride voltage-gated channel 2)
Sus scrofa (pig) : CLCN2 (chloride voltage-gated channel 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3184,346,185 - 184,361,650 (-)Ensembl
GRCh383184,346,185 - 184,361,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373184,063,973 - 184,079,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,547,034 - 185,562,085 (-)NCBINCBI36hg18NCBI36
Build 343185,547,095 - 185,561,969NCBI
Celera3182,504,875 - 182,520,290 (-)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,470,404 - 181,485,871 (-)NCBIHuRef
CHM1_13184,028,432 - 184,043,898 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CLCN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733366
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.