Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | affects expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of RABEP1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of RABEP1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in decreased expression of RABEP1 mRNA | CTD | PMID:15576828 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RABEP1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [RABEP1 protein binds to ESR1 protein] | CTD | PMID:27156127 | 17beta-estradiol | increases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of RABEP1 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RABEP1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RABEP1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of RABEP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RABEP1 mRNA | CTD | PMID:19770486 | 2-methylcholine | affects expression | ISO | RABEP1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RABEP1 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RABEP1 mRNA | CTD | PMID:26251327 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of RABEP1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of RABEP1 intron | CTD | PMID:30157460 | ammonium chloride | affects expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of RABEP1 mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RABEP1 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of RABEP1 mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of RABEP1 mRNA | CTD | PMID:22378314 | azoxystrobin | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of RABEP1 mRNA | CTD | PMID:20064835 | benzo[a]pyrene | affects methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RABEP1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of RABEP1 mRNA | CTD | PMID:22228805 | benzo[e]pyrene | increases methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of RABEP1 intron | CTD | PMID:30157460 | bisphenol A | increases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of RABEP1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of RABEP1 gene | CTD | PMID:31601247 | bisphenol A | increases methylation | ISO | Rabep1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of RABEP1 gene | CTD | PMID:28505145 | Brodifacoum | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of RABEP1 protein | CTD | PMID:28903499 | caffeine | decreases phosphorylation | ISO | RABEP1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of RABEP1 protein | CTD | PMID:35688186 | carbamazepine | affects expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of RABEP1 mRNA | CTD | PMID:25979313 | carbon nanotube | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Nanotubes and Carbon results in increased expression of RABEP1 mRNA | CTD | PMID:15585362 | chlorpyrifos | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA | CTD | PMID:33854195 | cisplatin | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of RABEP1 mRNA | CTD | PMID:21858171 | coumarin | decreases phosphorylation | ISO | RABEP1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of RABEP1 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RABEP1 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of RABEP1 mRNA | CTD | PMID:19770486 | diazinon | affects expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Diazinon affects the expression of RABEP1 mRNA | CTD | PMID:22546817 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of RABEP1 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RABEP1 mRNA | CTD | PMID:28302478 | dieldrin | affects expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Dieldrin affects the expression of RABEP1 mRNA | CTD | PMID:22546817 | dorsomorphin | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RABEP1 mRNA | CTD | PMID:27188386 | enzyme inhibitor | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RABEP1 protein | CTD | PMID:23301498 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of RABEP1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of RABEP1 mRNA | CTD | PMID:23649840 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of RABEP1 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | RABEP1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of RABEP1 protein | CTD | PMID:37730182 | furan | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | furan results in decreased expression of RABEP1 mRNA | CTD | PMID:26194646 | geldanamycin | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of RABEP1 mRNA | CTD | PMID:26705709 | gentamycin | increases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of RABEP1 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA | CTD | PMID:33854195 | hypochlorous acid | increases expression | EXP | | 6480464 | Hypochlorous Acid results in increased expression of RABEP1 mRNA | CTD | PMID:19376150 | imidacloprid | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA | CTD | PMID:33854195 | ivermectin | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RABEP1 protein | CTD | PMID:32959892 | methamphetamine | increases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Methamphetamine results in increased expression of RABEP1 protein | CTD | PMID:19826936 | methapyrilene | increases methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of RABEP1 intron | CTD | PMID:30157460 | methotrexate | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of RABEP1 mRNA | CTD | PMID:24449571 | nimesulide | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | nimesulide results in decreased expression of RABEP1 mRNA | CTD | PMID:24136188 | oxaliplatin | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RABEP1 mRNA | CTD | PMID:25729387 | PCB138 | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | piroxicam | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of RABEP1 mRNA | CTD | PMID:21858171 | resveratrol | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RABEP1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RABEP1 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of RABEP1 mRNA | CTD | PMID:36209798 | sunitinib | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RABEP1 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of RABEP1 mRNA | CTD | PMID:31758290 | thiabendazole | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA | CTD | PMID:33854195 | topotecan | decreases expression | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of RABEP1 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | ISO | Rabep1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RABEP1 mRNA | CTD | PMID:25729387 | trichostatin A | decreases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RABEP1 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RABEP1 mRNA | CTD | PMID:27188386 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of RABEP1 mRNA | CTD | PMID:30912803 | valproic acid | increases expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RABEP1 mRNA | CTD | PMID:23179753 and PMID:29154799 | valproic acid | affects splicing | ISO | Rabep1 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of RABEP1 mRNA | CTD | PMID:29427782 | valproic acid | affects expression | ISO | RABEP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RABEP1 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | RABEP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of RABEP1 gene | CTD | PMID:29154799 | zinc atom | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of RABEP1 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | RABEP1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of RABEP1 mRNA | CTD | PMID:18593933 | |