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Gene: GNAZ (G protein subunit alpha z) Homo sapiens
Symbol: GNAZ
Name: G protein subunit alpha z
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to localize to heterotrimeric G-protein complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: g(x) alpha chain; guanine nucleotide binding protein (G protein), alpha z polypeptide; guanine nucleotide-binding protein G(z) subunit alpha; gz-alpha; transducin alpha
Mus musculus (house mouse) : Gnaz (guanine nucleotide binding protein, alpha z subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnaz (G protein subunit alpha z)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnaz (G protein subunit alpha z)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAZ (G protein subunit alpha z)
Canis lupus familiaris (dog) : GNAZ (G protein subunit alpha z)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnaz (G protein subunit alpha z)
Sus scrofa (pig) : GNAZ (G protein subunit alpha z)
Chlorocebus sabaeus (African green monkey) : GNAZ (G protein subunit alpha z)
Heterocephalus glaber (naked mole-rat) : Gnaz (G protein subunit alpha z)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2223,070,519 - 23,125,032 (+)EnsemblGRCh38hg38GRCh38
GRCh382223,070,519 - 23,125,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372223,412,669 - 23,467,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362221,742,669 - 21,797,224 (+)NCBINCBI36hg18NCBI36
Build 342221,737,222 - 21,791,775NCBI
Celera227,227,239 - 7,281,792 (+)NCBI
Cytogenetic Map22q11.22-q11.23NCBI
HuRef226,380,502 - 6,434,961 (+)NCBIHuRef
CHM1_12223,424,953 - 23,479,508 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GNAZ
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733341
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.