Entpd1 (ectonucleoside triphosphate diphosphohydrolase 1) - Rat Genome Database

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Gene: Entpd1 (ectonucleoside triphosphate diphosphohydrolase 1) Mus musculus
Analyze
Symbol: Entpd1
Name: ectonucleoside triphosphate diphosphohydrolase 1
RGD ID: 733330
MGI Page MGI
Description: Enables ADP phosphatase activity and ribonucleoside triphosphate phosphatase activity. Involved in ADP catabolic process. Acts upstream of or within G protein-coupled receptor signaling pathway; nucleoside phosphate catabolic process; and platelet activation. Located in basement membrane. Is active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610206B08Rik; AA408691; ATP diphosphohydrolase; ATP-DPH; ATPDase; Cd39; CD39 antigen; E130009M23Rik; ecto-apyrase; ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; ectoa; ectoapyrase; lymphoid cell activation antigen; NTPDa; NTPDase 1; NTPDase-1; NTPDase1; nucleoside triphosphate diphosphohydrolase 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391940,600,810 - 40,730,046 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1940,600,810 - 40,730,046 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381940,612,366 - 40,741,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1940,612,366 - 40,741,602 (+)Ensemblmm10GRCm38
MGSCv371940,734,284 - 40,816,092 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361940,751,297 - 40,794,913 (+)NCBIMGSCv36mm8
Celera1941,460,982 - 41,543,158 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1934.25NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
amphetamine  (EXP,ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
carbon nanotube  (EXP)
cerivastatin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cyhalothrin  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
deguelin  (ISO)
dibenzofuran  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
ethylbenzene  (ISO)
flavonoids  (ISO)
formaldehyde  (ISO)
gentamycin  (ISO)
glucose  (EXP)
isoprenaline  (EXP)
lead(0)  (ISO)
linuron  (EXP)
lipopolysaccharide  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
pirinixic acid  (EXP)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP,ISO)
toluene  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
tungsten  (EXP)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Plasma hemopexin activity in pregnancy and preeclampsia. Bakker WW, etal., Hypertens Pregnancy. 2007;26(2):227-39.
2. Increased NTPDase activity in lymphocytes during experimental sepsis. Bertoncheli Cde M, etal., ScientificWorldJournal. 2012;2012:941906. doi: 10.1100/2012/941906. Epub 2012 May 3.
3. Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat. Braun N, etal., J Neurosci. 1998 Jul 1;18(13):4891-900.
4. Hypo-and hyperthyroidism affect the ATP, ADP and AMP hydrolysis in rat hippocampal and cortical slices. Bruno AN, etal., Neurosci Res. 2005 May;52(1):61-8.
5. Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Enjyoji K, etal., Nat Med 1999 Sep;5(9):1010-7.
6. Modulation of nucleoside triphosphate diphosphohydrolase-1 (NTPDase-1)cd39 in xenograft rejection. Imai M, etal., Mol Med. 1999 Nov;5(11):743-52.
7. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8. Overexpression of CD39/nucleoside triphosphate diphosphohydrolase-1 decreases smooth muscle cell proliferation and prevents neointima formation after angioplasty. Koziak K, etal., J Thromb Haemost. 2008 Jul;6(7):1191-7. doi: 10.1111/j.1538-7836.2008.03019.x. Epub 2008 Jul 1.
9. Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis. Lavrnja I, etal., Neurochem Int. 2009 Sep;55(4):193-8. doi: 10.1016/j.neuint.2009.02.013. Epub 2009 Mar 5.
10. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Enhanced NTPDase and 5'-nucleotidase activities in diabetes mellitus and iron-overload model. Miron VR, etal., Mol Cell Biochem. 2007 Apr;298(1-2):101-7. Epub 2006 Nov 21.
14. Up-regulation of ectonucleotidase activity after cortical stab injury in rats. Nedeljkovic N, etal., Cell Biol Int. 2006 Jun;30(6):541-6. Epub 2006 Mar 22.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. Mouse MP Annotation Import Pipeline RGD automated import pipeline
19. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Activities of enzymes that hydrolyze adenine nucleotides in platelets from rats experimentally demyelinated with ethidium bromide and treated with interferon-beta. Spanevello RM, etal., Life Sci. 2007 Feb 27;80(12):1109-14. Epub 2006 Dec 8.
22. Characterization of brain ecto-apyrase: evidence for only one ecto-apyrase (CD39) gene. Wang TF, etal., Brain Res Mol Brain Res 1997 Jul;47(1-2):295-302.
23. Purinergic receptor activation inhibits osmotic glial cell swelling in the diabetic rat retina. Wurm A, etal., Exp Eye Res. 2008 Oct;87(4):385-93. doi: 10.1016/j.exer.2008.07.004. Epub 2008 Jul 18.
24. Lipopolysaccharide alters ecto-ATP-diphosphohydrolase and causes relocation of its reaction product in experimental intrahepatic cholestasis. Zinchuk VS, etal., Cell Tissue Res. 2001 Apr;304(1):103-9.
Additional References at PubMed
PMID:7930580   PMID:9730622   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11748109   PMID:11927941   PMID:11929769   PMID:11956240   PMID:12477932   PMID:14610273  
PMID:14681479   PMID:14691545   PMID:14730706   PMID:14983235   PMID:15319286   PMID:15632415   PMID:16141072   PMID:16141073   PMID:17038639   PMID:17449799   PMID:17473221   PMID:17502665  
PMID:17548651   PMID:17565006   PMID:17823293   PMID:17909107   PMID:18036594   PMID:18098126   PMID:18256308   PMID:18537971   PMID:18567823   PMID:18713747   PMID:18752325   PMID:18804472  
PMID:18812468   PMID:18838482   PMID:19074640   PMID:19095759   PMID:19116950   PMID:19327391   PMID:19381014   PMID:19427686   PMID:19520738   PMID:19640930   PMID:19805374   PMID:20146261  
PMID:20201036   PMID:20207994   PMID:20430891   PMID:20546740   PMID:20936356   PMID:21176405   PMID:21233276   PMID:21677750   PMID:21807070   PMID:21873635   PMID:21967895   PMID:22184407  
PMID:22383490   PMID:22406269   PMID:22421436   PMID:22514659   PMID:22613024   PMID:22637533   PMID:22859060   PMID:23208703   PMID:23349052   PMID:23362118   PMID:23364452   PMID:23452076  
PMID:23600369   PMID:23870672   PMID:23908469   PMID:23995234   PMID:24194600   PMID:24266925   PMID:25043484   PMID:25160621   PMID:25184735   PMID:25208846   PMID:25318477   PMID:25318479  
PMID:25558978   PMID:25661084   PMID:25780038   PMID:25877509   PMID:26005855   PMID:26121751   PMID:26491691   PMID:26541524   PMID:27208163   PMID:27322617   PMID:27430240   PMID:27623510  
PMID:27626380   PMID:27730511   PMID:27756600   PMID:27760760   PMID:28060378   PMID:28097233   PMID:28376099   PMID:28432149   PMID:28487312   PMID:28554875   PMID:28742222   PMID:28746349  
PMID:29066514   PMID:29236227   PMID:29404503   PMID:29456159   PMID:29463714   PMID:29516286   PMID:29742141   PMID:30244433   PMID:30718407   PMID:30816804   PMID:30962630   PMID:30973865  
PMID:30990798   PMID:31069159   PMID:31188623   PMID:31243614   PMID:31545401   PMID:31639617   PMID:31699796   PMID:31736956   PMID:31974050   PMID:31992567   PMID:32133764   PMID:32304668  
PMID:32452837   PMID:32773283   PMID:33208731   PMID:33498759   PMID:33653920   PMID:33683190   PMID:34033815   PMID:34321999   PMID:34335618   PMID:34473957   PMID:34973190   PMID:35364055  
PMID:35613855   PMID:35926464   PMID:36240436   PMID:37894719   PMID:38117410   PMID:38355793   PMID:38545102   PMID:38683845   PMID:38953295   PMID:38975728   PMID:39843911  


Genomics

Comparative Map Data
Entpd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391940,600,810 - 40,730,046 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1940,600,810 - 40,730,046 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381940,612,366 - 40,741,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1940,612,366 - 40,741,602 (+)Ensemblmm10GRCm38
MGSCv371940,734,284 - 40,816,092 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361940,751,297 - 40,794,913 (+)NCBIMGSCv36mm8
Celera1941,460,982 - 41,543,158 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1934.25NCBI
ENTPD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381095,694,186 - 95,877,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1095,711,779 - 95,877,266 (+)Ensemblhg38GRCh38
GRCh371097,471,521 - 97,637,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361097,461,526 - 97,627,013 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341097,505,905 - 97,616,454NCBI
Celera1091,256,620 - 91,378,232 (+)NCBICelera
Cytogenetic Map10q24.1NCBI
HuRef1091,099,222 - 91,264,599 (+)NCBIHuRef
CHM1_11097,753,378 - 97,918,865 (+)NCBICHM1_1
T2T-CHM13v2.01096,573,293 - 96,756,364 (+)NCBIT2T-CHM13v2.0
Entpd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,374,810 - 249,502,310 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1249,374,836 - 249,502,317 (+)EnsemblGRCr8
mRatBN7.21239,425,515 - 239,552,323 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,425,430 - 239,552,317 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1247,609,333 - 247,694,716 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01254,313,067 - 254,391,812 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01246,966,100 - 247,044,845 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01259,692,020 - 259,818,922 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,739,955 - 259,819,494 (+)Ensemblrn6Rnor6.0
Rnor_5.01267,401,518 - 267,432,848 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01267,183,177 - 267,259,665 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41245,783,750 - 245,887,419 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1235,318,582 - 235,397,159 (+)NCBICelera
RGSC_v3.11245,894,247 - 246,001,894 (+)NCBI
Cytogenetic Map1q54NCBI
Entpd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555072,036,050 - 2,137,377 (+)Ensembl
ChiLan1.0NW_0049555072,035,918 - 2,141,327 (+)NCBIChiLan1.0ChiLan1.0
ENTPD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28107,597,147 - 107,804,840 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110107,602,465 - 107,811,326 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01092,365,267 - 92,511,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11095,871,671 - 95,983,257 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1095,828,094 - 95,983,257 (+)EnsemblpanPan2panpan1.1
ENTPD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1289,181,851 - 9,311,835 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl289,211,050 - 9,323,939 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha289,357,708 - 9,489,400 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0289,444,087 - 9,575,820 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl289,475,293 - 9,595,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1289,160,534 - 9,292,221 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0289,220,048 - 9,351,993 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0289,363,303 - 9,495,027 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
ENTPD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14107,263,449 - 107,389,010 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.114107,263,546 - 107,390,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214116,897,330 - 117,022,541 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENTPD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1988,921,826 - 89,034,418 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl988,922,007 - 89,032,880 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604849,731,265 - 49,906,385 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Entpd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247377,084,818 - 7,191,918 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247377,011,792 - 7,193,903 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Entpd1
4934 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2062
Count of miRNA genes:813
Interacting mature miRNAs:1056
Transcripts:ENSMUST00000112231, ENSMUST00000127268, ENSMUST00000127828, ENSMUST00000134063, ENSMUST00000137508, ENSMUST00000144080, ENSMUST00000151726, ENSMUST00000155988, ENSMUST00000156598, ENSMUST00000160286, ENSMUST00000163023
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193918406461420004Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193959606661420004Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
13504736Ifvrq6_minfluenza virus resistance QTL 6 (mouse)193690291044913949Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193601694446761521Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192513600242388916Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse

Markers in Region
RH126699  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381940,707,769 - 40,707,968UniSTSGRCm38
MGSCv371940,782,259 - 40,782,458UniSTSGRCm37
Celera1941,509,043 - 41,509,242UniSTS
Cytogenetic Map19C3UniSTS
cM Map1935.5UniSTS
Whitehead/MRC_RH19415.45UniSTS
AF037366  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381940,739,188 - 40,739,279UniSTSGRCm38
MGSCv371940,813,678 - 40,813,769UniSTSGRCm37
Celera1941,540,744 - 41,540,835UniSTS
Cytogenetic Map19C3UniSTS
cM Map1935.5UniSTS
Whitehead/MRC_RH19415.34UniSTS
RH124743  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381940,739,181 - 40,739,448UniSTSGRCm38
MGSCv371940,813,671 - 40,813,938UniSTSGRCm37
Celera1941,540,737 - 41,541,004UniSTS
Cytogenetic Map19C3UniSTS
cM Map1935.5UniSTS
RH125812  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381940,739,227 - 40,739,442UniSTSGRCm38
MGSCv371940,813,717 - 40,813,932UniSTSGRCm37
Celera1941,540,783 - 41,540,998UniSTS
Cytogenetic Map19C3UniSTS
cM Map1935.5UniSTS
Whitehead/MRC_RH19414.82UniSTS
Entpd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3UniSTS
cM Map1934.25UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001304721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC166063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF037366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN696192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000112231   ⟹   ENSMUSP00000107850
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,648,214 - 40,730,046 (+)Ensembl
GRCm38.p6 Ensembl1940,659,770 - 40,741,602 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127268   ⟹   ENSMUSP00000116895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,714,494 - 40,728,199 (+)Ensembl
GRCm38.p6 Ensembl1940,726,050 - 40,739,755 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127828   ⟹   ENSMUSP00000117213
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,648,243 - 40,713,470 (+)Ensembl
GRCm38.p6 Ensembl1940,659,799 - 40,725,026 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134063   ⟹   ENSMUSP00000116285
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,600,841 - 40,728,238 (+)Ensembl
GRCm38.p6 Ensembl1940,612,397 - 40,739,794 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,670,111 - 40,711,637 (+)Ensembl
GRCm38.p6 Ensembl1940,681,667 - 40,723,193 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144080
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,648,937 - 40,711,541 (+)Ensembl
GRCm38.p6 Ensembl1940,660,493 - 40,723,097 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151726
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,724,628 - 40,725,309 (+)Ensembl
GRCm38.p6 Ensembl1940,736,184 - 40,736,865 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,648,643 - 40,699,681 (+)Ensembl
GRCm38.p6 Ensembl1940,660,199 - 40,711,237 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156598   ⟹   ENSMUSP00000116349
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,648,288 - 40,727,527 (+)Ensembl
GRCm38.p6 Ensembl1940,659,844 - 40,739,083 (+)Ensembl
Ensembl Acc Id: ENSMUST00000160286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,600,833 - 40,604,162 (+)Ensembl
GRCm38.p6 Ensembl1940,612,389 - 40,615,718 (+)Ensembl
Ensembl Acc Id: ENSMUST00000163023
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1940,600,810 - 40,602,589 (+)Ensembl
GRCm38.p6 Ensembl1940,612,366 - 40,614,145 (+)Ensembl
RefSeq Acc Id: NM_001304721   ⟹   NP_001291650
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,600,810 - 40,730,046 (+)NCBI
GRCm381940,612,366 - 40,741,602 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009848   ⟹   NP_033978
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,648,214 - 40,730,046 (+)NCBI
GRCm381940,659,770 - 40,741,602 (+)NCBI
MGSCv371940,734,284 - 40,816,092 (+)RGD
Celera1941,460,982 - 41,543,158 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526618   ⟹   XP_006526681
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,648,914 - 40,729,773 (+)NCBI
GRCm381940,660,456 - 40,741,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006526619   ⟹   XP_006526682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,648,198 - 40,729,773 (+)NCBI
GRCm381940,659,766 - 40,741,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006526620   ⟹   XP_006526683
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,648,595 - 40,729,773 (+)NCBI
GRCm381940,660,159 - 40,741,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318047   ⟹   XP_017173536
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391940,648,977 - 40,729,773 (+)NCBI
GRCm381940,660,745 - 40,741,601 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033978   ⟸   NM_009848
- Peptide Label: isoform 2
- UniProtKB: P55772 (UniProtKB/Swiss-Prot),   Q544U5 (UniProtKB/TrEMBL),   Q921Q6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006526682   ⟸   XM_006526619
- Peptide Label: isoform X1
- UniProtKB: Q8CEB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006526683   ⟸   XM_006526620
- Peptide Label: isoform X1
- UniProtKB: Q8CEB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006526681   ⟸   XM_006526618
- Peptide Label: isoform X1
- UniProtKB: Q8CEB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291650   ⟸   NM_001304721
- Peptide Label: isoform 1
- UniProtKB: Q8CDV7 (UniProtKB/TrEMBL),   Q921Q6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173536   ⟸   XM_017318047
- Peptide Label: isoform X1
- UniProtKB: Q8CEB1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000117213   ⟸   ENSMUST00000127828
Ensembl Acc Id: ENSMUSP00000116895   ⟸   ENSMUST00000127268
Ensembl Acc Id: ENSMUSP00000107850   ⟸   ENSMUST00000112231
Ensembl Acc Id: ENSMUSP00000116285   ⟸   ENSMUST00000134063
Ensembl Acc Id: ENSMUSP00000116349   ⟸   ENSMUST00000156598

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55772-F1-model_v2 AlphaFold P55772 1-510 view protein structure

Promoters
RGD ID:13679458
Promoter ID:EPDNEW_M23878
Type:multiple initiation site
Name:Entpd1_1
Description:Mus musculus ectonucleoside triphosphate diphosphohydrolase 1, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381940,659,794 - 40,659,854EPDNEW
RGD ID:6830010
Promoter ID:MM_KWN:27032
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung,   Spleen
Transcripts:OTTMUST00000072024,   OTTMUST00000072027,   OTTMUST00000072028,   OTTMUST00000072029,   OTTMUST00000072031
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361940,734,551 - 40,735,247 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102805 AgrOrtholog
Ensembl Genes ENSMUSG00000048120 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000112231 ENTREZGENE
  ENSMUST00000112231.9 UniProtKB/Swiss-Prot
  ENSMUST00000134063 ENTREZGENE
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
  Exopolyphosphatase. Domain 2 UniProtKB/Swiss-Prot
InterPro GDA1_CD39_NTPase UniProtKB/Swiss-Prot
KEGG Report mmu:12495 UniProtKB/Swiss-Prot
MGD MGI:102805 ENTREZGENE
NCBI Gene 12495 ENTREZGENE
PANTHER ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 UniProtKB/Swiss-Prot
  PTHR11782 UniProtKB/Swiss-Prot
Pfam GDA1_CD39 UniProtKB/Swiss-Prot
PhenoGen Entpd1 PhenoGen
PROSITE GDA1_CD39_NTPASE UniProtKB/Swiss-Prot
UniProt D6RFA9_MOUSE UniProtKB/TrEMBL
  D6RHQ2_MOUSE UniProtKB/TrEMBL
  ENTP1_MOUSE UniProtKB/Swiss-Prot
  F7B9M9_MOUSE UniProtKB/TrEMBL
  P55772 ENTREZGENE
  Q544U5 ENTREZGENE, UniProtKB/TrEMBL
  Q8CDV7 ENTREZGENE, UniProtKB/TrEMBL
  Q8CEB1 ENTREZGENE, UniProtKB/TrEMBL
  Q921Q6 ENTREZGENE, UniProtKB/TrEMBL