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Gene: Grb7 (growth factor receptor bound protein 7) Mus musculus
Symbol: Grb7
Name: growth factor receptor bound protein 7
Description: Predicted to have identical protein binding activity; phosphatidylinositol binding activity; and protein kinase binding activity. Involved in negative regulation of translation and stress granule assembly. Localizes to the cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GRB7 (growth factor receptor bound protein 7); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epidermal growth factor receptor GRB-7; GRB7 adapter protein; growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); KIAA4028; MGC78181; mKIAA4028
Homo sapiens (human) : GRB7 (growth factor receptor bound protein 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grb7 (growth factor receptor bound protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb7 (growth factor receptor bound protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB7 (growth factor receptor bound protein 7)
Canis lupus familiaris (dog) : GRB7 (growth factor receptor bound protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb7 (growth factor receptor bound protein 7)
Sus scrofa (pig) : GRB7 (growth factor receptor bound protein 7)
Chlorocebus sabaeus (African green monkey) : GRB7 (growth factor receptor bound protein 7)
Heterocephalus glaber (naked mole-rat) : Grb7 (growth factor receptor bound protein 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1198,446,394 - 98,455,373 (+)EnsemblGRCm38mm10GRCm38
GRCm381198,446,834 - 98,455,373 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371198,308,148 - 98,316,687 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,262,981 - 98,271,463 (+)NCBImm8
Celera11108,101,038 - 108,109,577 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Grb7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733274
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.