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Gene: Grb7 (growth factor receptor bound protein 7) Mus musculus
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Symbol: Grb7
Name: growth factor receptor bound protein 7
Description: Predicted to have identical protein binding activity; phosphatidylinositol binding activity; and protein kinase binding activity. Involved in negative regulation of translation and stress granule assembly. Localizes to the cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GRB7 (growth factor receptor bound protein 7); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epidermal growth factor receptor GRB-7; GRB7 adapter protein; growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); KIAA4028; MGC78181; mKIAA4028
Orthologs:
Homo sapiens (human) : GRB7 (growth factor receptor bound protein 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grb7 (growth factor receptor bound protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb7 (growth factor receptor bound protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB7 (growth factor receptor bound protein 7)
Canis lupus familiaris (dog) : GRB7 (growth factor receptor bound protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb7 (growth factor receptor bound protein 7)
Sus scrofa (pig) : GRB7 (growth factor receptor bound protein 7)
Chlorocebus sabaeus (African green monkey) : GRB7 (growth factor receptor bound protein 7)
Heterocephalus glaber (naked mole-rat) : Grb7 (growth factor receptor bound protein 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1198,446,394 - 98,455,373 (+)EnsemblGRCm38mm10GRCm38
GRCm381198,446,834 - 98,455,373 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371198,308,148 - 98,316,687 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,262,981 - 98,271,463 (+)NCBImm8
Celera11108,101,038 - 108,109,577 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Grb7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733274
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.