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Gene: LRRC15 (leucine rich repeat containing 15) Homo sapiens
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Symbol: LRRC15
Name: leucine rich repeat containing 15
Description: Exhibits collagen binding activity; fibronectin binding activity; and laminin binding activity. Involved in negative regulation of protein localization to plasma membrane; positive regulation of cell migration; and receptor-mediated virion attachment to host cell. Localizes to extracellular exosome. Colocalizes with collagen-containing extracellular matrix; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B2; calcitriol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hLib; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; leucine-rich repeat-containing protein 15; LIB
Orthologs:
Mus musculus (house mouse) : Lrrc15 (leucine rich repeat containing 15)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lrrc15 (leucine rich repeat containing 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrc15 (leucine rich repeat containing 15)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRC15 (leucine rich repeat containing 15)
Canis lupus familiaris (dog) : LRRC15 (leucine rich repeat containing 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrc15 (leucine rich repeat containing 15)
Sus scrofa (pig) : LRRC15 (leucine rich repeat containing 15)
Chlorocebus sabaeus (African green monkey) : LRRC15 (leucine rich repeat containing 15)
Heterocephalus glaber (naked mole-rat) : Lrrc15 (leucine rich repeat containing 15)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3194,355,247 - 194,369,743 (-)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl3194,355,249 - 194,369,743 (-)EnsemblGRCh38hg38GRCh38
GRCh383194,355,249 - 194,369,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373194,075,976 - 194,090,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363195,557,273 - 195,571,761 (-)NCBINCBI36hg18NCBI36
Build 343195,557,280 - 195,571,769NCBI
Celera3192,490,979 - 192,505,408 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3191,455,388 - 191,469,818 (-)NCBIHuRef
CHM1_13194,038,840 - 194,053,338 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LRRC15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733250
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.