Tbxa2r (thromboxane A2 receptor) - Rat Genome Database

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Gene: Tbxa2r (thromboxane A2 receptor) Mus musculus
Analyze
Symbol: Tbxa2r
Name: thromboxane A2 receptor
RGD ID: 733229
MGI Page MGI
Description: Enables thromboxane receptor activity. Acts upstream of or within several processes, including positive regulation of smooth muscle contraction; regulation of vasoconstriction; and response to lipopolysaccharide. Predicted to be located in acrosomal vesicle and nuclear speck. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease; asthma; and blood platelet disease. Orthologous to human TBXA2R (thromboxane A2 receptor).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MGC107665; prostanoid TP receptor; T; thromboxane prostanoid; TP; Tp receptor; TXA2; TXA2 receptor; TXA2-R
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,164,102 - 81,171,008 (+)NCBIGRCm39mm39
GRCm39 Ensembl1081,164,565 - 81,171,006 (+)Ensembl
GRCm381081,328,268 - 81,335,174 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,328,731 - 81,335,172 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,791,476 - 80,797,917 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,731,860 - 80,738,301 (+)NCBImm8
Celera1082,349,466 - 82,355,970 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (ISO)
(S)-nicotine  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP)
8-epi-prostaglandin F2alpha  (EXP,ISO)
acetylsalicylic acid  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
Cuprizon  (ISO)
decabromodiphenyl ether  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
dioxygen  (EXP)
domitroban  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
entinostat  (ISO)
flavonoids  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
melittin  (ISO)
monocrotaline  (EXP)
N(gamma)-nitro-L-arginine methyl ester  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
oleic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (ISO)
phenol red  (ISO)
pirinixic acid  (EXP)
propanal  (ISO)
puromycin  (EXP)
raloxifene  (ISO)
Ramatroban  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sulforaphane  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
troglitazone  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
XL147  (EXP)
zinc sulfate  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Protective effects of BAY U 3405, a thromboxane A2 receptor antagonist, in endotoxin shock. Altavilla D, etal., Pharmacol Res. 1994 Aug-Sep;30(2):137-51.
2. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
3. Pharmacodynamics and antithrombotic effects after intravenous administration of the new thromboxane A2 receptor antagonist sodium 4-[[1-[[[(4-chlorophenyl)sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. Depin JC, etal., Arzneimittelforschung. 1994 Nov;44(11):1203-7.
4. Role for thromboxane receptors in angiotensin-II-induced hypertension. Francois H, etal., Hypertension. 2004 Feb;43(2):364-9. Epub 2004 Jan 12.
5. Thromboxane A2 receptor antagonist prevents pancreatic microvascular leakage in rats with caerulein-induced acute pancreatitis. Hirano T and Hirano K, Int J Surg Investig. 1999;1(3):203-10.
6. Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder. Hirata T, etal., J Clin Invest. 1994 Oct;94(4):1662-7.
7. Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor. Holt S, etal., Kidney Int. 1999 Jan;55(1):271-7.
8. IL-5 and thromboxane A2 receptor gene polymorphisms are associated with decreased pulmonary function in Korean children with atopic asthma. Hong SJ, etal., J Allergy Clin Immunol. 2005 Apr;115(4):758-63.
9. Effect of a novel thromboxane A2 receptor antagonist, S-145, on collagen-induced ECG changes and thrombocytopenia in rodents. Hori Y, etal., Jpn J Pharmacol. 1989 Jun;50(2):195-205.
10. Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma. Kim SH, etal., Clin Exp Allergy. 2005 May;35(5):585-90.
11. Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice. Kobayashi T, etal., J Clin Invest. 2004 Sep;114(6):784-94.
12. Thromboxane A2 receptor gene polymorphism is associated with the serum concentration of cat-specific immunoglobulin E as well as the development and severity of asthma in Chinese children. Leung TF, etal., Pediatr Allergy Immunol. 2002 Feb;13(1):10-7.
13. Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation. Liu T, etal., Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12692-7. doi: 10.1073/pnas.1207816109. Epub 2012 Jul 16.
14. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
15. MGDs mouse GO annotations MGD data from the GO Consortium
16. MGD IEA MGD IEA
17. [Study of thromboxane A2 antagonist reduction in the treatment of patients with perennial allergic rhinitis]. Narita S, etal., Arerugi. 2004 Jun;53(6):601-4.
18. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
19. Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia. Olanoff LS, etal., J Cardiovasc Pharmacol. 1985 Jan-Feb;7(1):114-20.
20. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints. Puttagunta R, etal., Genome Res 2000 Sep;10(9):1369-80.
23. Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides. Remuzzi G, etal., J Exp Med. 1994 Nov 1;180(5):1967-72.
24. Mouse MP Annotation Import Pipeline RGD automated import pipeline
25. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
27. Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia. Takayama K, etal., Nat Med. 2005 May;11(5):562-6. Epub 2005 Apr 17.
28. Genetic variants of the receptors for thromboxane A2 and IL-4 in atopic dermatitis. Tanaka K, etal., Biochem Biophys Res Commun. 2002 Apr 5;292(3):776-80.
29. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. Thomas DW, etal., J Clin Invest. 1998 Dec 1;102(11):1994-2001.
30. Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression. Traupe T, etal., J Hypertens. 2002 Nov;20(11):2239-45.
31. Therapeutic intervention in a rat model of adult respiratory distress syndrome: III. Cyclooxygenase pathway inhibition. Turner CR, etal., Circ Shock. 1991 Jun;34(2):270-7.
32. Thromboxane A2 from Kupffer cells contributes to the hyperresponsiveness of hepatic portal circulation to endothelin-1 in endotoxemic rats. Xu H, etal., Am J Physiol Gastrointest Liver Physiol. 2005 Feb;288(2):G277-83.
Additional References at PubMed
PMID:1375456   PMID:1387435   PMID:7910583   PMID:8228829   PMID:8831666   PMID:8836152   PMID:8889548   PMID:9336326   PMID:9719483   PMID:9774479   PMID:10037795   PMID:10079195  
PMID:10349636   PMID:10508233   PMID:10589702   PMID:10691801   PMID:10894809   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11226403   PMID:11782353   PMID:11927615   PMID:11964481  
PMID:12446460   PMID:12477932   PMID:12778172   PMID:12796499   PMID:12925702   PMID:12958152   PMID:14627611   PMID:14662837   PMID:14752832   PMID:15213069   PMID:15339984   PMID:15635218  
PMID:15655126   PMID:15905461   PMID:15925391   PMID:15983244   PMID:16141072   PMID:16141073   PMID:16154102   PMID:16243899   PMID:16267259   PMID:16380483   PMID:16385086   PMID:16602821  
PMID:16788103   PMID:16973501   PMID:17097058   PMID:17158227   PMID:17242161   PMID:17306791   PMID:17612649   PMID:17942572   PMID:18000613   PMID:18206890   PMID:18448655   PMID:18514659  
PMID:18684890   PMID:18800000   PMID:18802021   PMID:18938093   PMID:18996116   PMID:19325001   PMID:19735918   PMID:19966781   PMID:20162250   PMID:20566843   PMID:20947827   PMID:21364319  
PMID:21449636   PMID:21460251   PMID:21749493   PMID:21873635   PMID:21984570   PMID:22008592   PMID:22064668   PMID:22086927   PMID:22206755   PMID:22222195   PMID:22296266   PMID:22503974  
PMID:22879580   PMID:23082158   PMID:23150508   PMID:23162015   PMID:23203967   PMID:23255603   PMID:23624557   PMID:24085850   PMID:24244016   PMID:24821912   PMID:25457549   PMID:25921763  
PMID:25921923   PMID:25935870   PMID:26018088   PMID:26410627   PMID:26890419   PMID:26957525   PMID:27818280   PMID:28165064   PMID:30277822   PMID:30300909   PMID:31129913   PMID:31785598  
PMID:33567865  


Genomics

Comparative Map Data
Tbxa2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,164,102 - 81,171,008 (+)NCBIGRCm39mm39
GRCm39 Ensembl1081,164,565 - 81,171,006 (+)Ensembl
GRCm381081,328,268 - 81,335,174 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,328,731 - 81,335,172 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,791,476 - 80,797,917 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,731,860 - 80,738,301 (+)NCBImm8
Celera1082,349,466 - 82,355,970 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
TBXA2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,594,507 - 3,606,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl193,594,507 - 3,606,875 (-)EnsemblGRCh38hg38GRCh38
GRCh37193,594,505 - 3,606,873 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,545,504 - 3,557,658 (-)NCBINCBI36hg18NCBI36
Build 34193,545,503 - 3,557,658NCBI
Celera193,531,342 - 3,543,669 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,359,876 - 3,372,152 (-)NCBIHuRef
CHM1_1193,594,158 - 3,606,423 (-)NCBICHM1_1
T2T-CHM13v2.0193,572,690 - 3,584,998 (-)NCBI
Tbxa2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.278,383,347 - 8,390,753 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl78,383,378 - 8,388,176 (-)Ensembl
Rnor_6.0711,253,153 - 11,259,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,253,180 - 11,257,977 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,419,887 - 11,425,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,867,739 - 9,872,536 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.179,867,738 - 9,872,536 (-)NCBI
Celera76,572,330 - 6,577,127 (-)NCBICelera
Cytogenetic Map7q11NCBI
Tbxa2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,539,889 - 5,557,441 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,539,382 - 5,557,441 (-)NCBIChiLan1.0ChiLan1.0
TBXA2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1193,572,454 - 3,581,924 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,570,290 - 3,581,924 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0192,621,606 - 2,632,800 (-)NCBIMhudiblu_PPA_v0panPan3
TBXA2R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,819,866 - 55,829,395 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,824,410 - 55,828,980 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,545,953 - 55,554,659 (+)NCBI
ROS_Cfam_1.02056,480,706 - 56,489,446 (+)NCBI
ROS_Cfam_1.0 Ensembl2056,480,655 - 56,490,031 (+)Ensembl
UMICH_Zoey_3.12055,536,340 - 55,545,063 (+)NCBI
UNSW_CanFamBas_1.02056,019,809 - 56,028,498 (+)NCBI
UU_Cfam_GSD_1.02056,218,510 - 56,227,219 (+)NCBI
Tbxa2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,786,562 - 215,793,960 (+)NCBI
SpeTri2.0NW_0049365882,040,712 - 2,044,635 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBXA2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,068,698 - 75,087,731 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,068,413 - 75,081,305 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103233689
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,354,358 - 3,365,779 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl63,355,314 - 3,359,761 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660815,119,245 - 5,134,213 (+)NCBIVero_WHO_p1.0
Tbxa2r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,291,167 - 6,309,482 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248286,291,010 - 6,312,438 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI413759  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381081,335,281 - 81,335,427UniSTSGRCm38
MGSCv371080,798,026 - 80,798,172UniSTSGRCm37
Celera1082,356,079 - 82,356,225UniSTS
Cytogenetic Map10C1UniSTS
cM Map1043.0UniSTS
Whitehead/MRC_RH10926.13UniSTS
Tbxa2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381081,334,933 - 81,335,070UniSTSGRCm38
MGSCv371080,797,678 - 80,797,815UniSTSGRCm37
Celera1082,355,731 - 82,355,868UniSTS
Cytogenetic Map10C1UniSTS
cM Map1043.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:255
Count of miRNA genes:210
Interacting mature miRNAs:227
Transcripts:ENSMUST00000105325
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000105325   ⟹   ENSMUSP00000100962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1081,164,565 - 81,171,006 (+)Ensembl
GRCm38.p6 Ensembl1081,328,731 - 81,335,172 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220312   ⟹   ENSMUSP00000151447
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1081,164,565 - 81,171,006 (+)Ensembl
GRCm38.p6 Ensembl1081,328,731 - 81,335,172 (+)Ensembl
RefSeq Acc Id: NM_001277265   ⟹   NP_001264194
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391081,164,537 - 81,171,008 (+)NCBI
GRCm381081,328,703 - 81,335,174 (+)NCBI
Celera1082,349,438 - 82,355,972 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001358512   ⟹   NP_001345441
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391081,164,102 - 81,171,008 (+)NCBI
GRCm381081,328,268 - 81,335,174 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009325   ⟹   NP_033351
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391081,164,537 - 81,171,008 (+)NCBI
GRCm381081,328,703 - 81,335,174 (+)NCBI
MGSCv371080,791,476 - 80,797,917 (+)RGD
Celera1082,349,438 - 82,355,972 (+)NCBI
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033351   ⟸   NM_009325
- UniProtKB: P30987 (UniProtKB/Swiss-Prot),   Q5FW61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264194   ⟸   NM_001277265
- UniProtKB: P30987 (UniProtKB/Swiss-Prot),   Q5FW61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345441   ⟸   NM_001358512
- UniProtKB: P30987 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000100962   ⟸   ENSMUST00000105325
RefSeq Acc Id: ENSMUSP00000151447   ⟸   ENSMUST00000220312
Protein Domains
G_PROTEIN_RECEP_F1_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30987-F1-model_v2 AlphaFold P30987 1-341 view protein structure

Promoters
RGD ID:6819997
Promoter ID:MM_KWN:4980
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B6,   Spleen
Transcripts:NM_009325,   UC007GHH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361080,790,696 - 80,791,582 (+)MPROMDB
RGD ID:6848968
Promoter ID:MM_XEF:772
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_017054
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361080,792,226 - 80,792,726 (+)MPROMDB
RGD ID:8672790
Promoter ID:EPDNEW_M14426
Type:initiation region
Name:Tbxa2r_1
Description:Mus musculus thromboxane A2 receptor , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381081,328,732 - 81,328,792EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98496 AgrOrtholog
Ensembl Genes ENSMUSG00000034881 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000100962 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000151447 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000105325 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000220312 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thbox_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98496 ENTREZGENE
NCBI Gene 21390 ENTREZGENE
PANTHER PTHR11866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TBXA2R RGD
PhenoGen Tbxa2r PhenoGen
PRINTS PROSTANOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THROMBOXANER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P30987 ENTREZGENE
  Q5FW61 ENTREZGENE, UniProtKB/TrEMBL
  TA2R_MOUSE UniProtKB/Swiss-Prot