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Gene: PRKG2 (protein kinase cGMP-dependent 2) Homo sapiens
Symbol: PRKG2
Name: protein kinase cGMP-dependent 2
Description: Predicted to have cGMP-dependent protein kinase activity. Involved in protein phosphorylation. Predicted to localize to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cGK 2; cGK2; cGKII; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; PKG2; PRKGR2; protein kinase, cgmp- dependent, type ii; testicular tissue protein Li 99
Mus musculus (house mouse) : Prkg2 (protein kinase, cGMP-dependent, type II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkg2 (protein kinase cGMP-dependent 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkg2 (protein kinase cGMP-dependent 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKG2 (protein kinase cGMP-dependent 2)
Canis lupus familiaris (dog) : PRKG2 (protein kinase cGMP-dependent 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkg2 (protein kinase cGMP-dependent 2)
Sus scrofa (pig) : PRKG2 (protein kinase cGMP-dependent 2)
Chlorocebus sabaeus (African green monkey) : PRKG2 (protein kinase cGMP-dependent 2)
Heterocephalus glaber (naked mole-rat) : Prkg2 (protein kinase cGMP-dependent 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl481,087,370 - 81,215,117 (-)EnsemblGRCh38hg38GRCh38
GRCh38481,087,370 - 81,217,837 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37482,008,643 - 82,136,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36482,228,861 - 82,345,239 (-)NCBINCBI36hg18NCBI36
Build 34482,367,015 - 82,483,394NCBI
Celera479,302,549 - 79,418,932 (-)NCBI
Cytogenetic Map4q21.21NCBI
HuRef477,753,401 - 77,870,008 (-)NCBIHuRef
CHM1_1481,985,010 - 82,112,762 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRKG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733228
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.