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Gene: Crhr2 (corticotropin releasing hormone receptor 2) Mus musculus
Symbol: Crhr2
Name: corticotropin releasing hormone receptor 2
Description: Exhibits corticotrophin-releasing factor receptor activity and hormone activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of angiogenesis; and regulation of cAMP-mediated signaling. Localizes to Golgi apparatus; cell surface; and endoplasmic reticulum. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2); PARTICIPATES IN corticotropin-releasing hormone signaling pathway; G protein mediated signaling pathway via Galphas family; p38 MAPK signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: corticotropin releasing factor receptor type 2 beta; corticotropin-releasing factor 2; corticotropin-releasing factor receptor 2; corticotropin-releasing hormone receptor 2; CRF 2 receptor; CRF-R-2; CRF-R2; CRF-RB; CRFR-2; Crfr2; CRFR2alpha; CRFR2beta; CRH-R-2; CRH-R2
Homo sapiens (human) : CRHR2 (corticotropin releasing hormone receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crhr2 (corticotropin releasing hormone receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crhr2 (corticotropin releasing hormone receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CRHR2 (corticotropin releasing hormone receptor 2)
Canis lupus familiaris (dog) : CRHR2 (corticotropin releasing hormone receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crhr2 (corticotropin releasing hormone receptor 2)
Sus scrofa (pig) : CRHR2 (corticotropin releasing hormone receptor 2)
Heterocephalus glaber (naked mole-rat) : Crhr2 (corticotropin releasing hormone receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl655,090,049 - 55,133,016 (-)EnsemblGRCm38mm10GRCm38
GRCm38655,090,048 - 55,133,016 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37655,040,042 - 55,082,966 (-)NCBIGRCm37mm9NCBIm37
MGSCv36655,019,665 - 55,062,550 (-)NCBImm8
Celera655,625,289 - 55,668,208 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Crhr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733139
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.