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Gene: CALCRL (calcitonin receptor like receptor) Homo sapiens
Symbol: CALCRL
Name: calcitonin receptor like receptor
Description: Exhibits adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Localizes to several cellular components, including the calcitonin family receptor complex; endosome; and lysosome; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calcitonin gene-related peptide type 1 receptor; calcitonin receptor-like; calcitonin receptor-like receptor; CGRP type 1 receptor; CGRPR; CRLR; LMPHM8
Mus musculus (house mouse) : Calcrl (calcitonin receptor-like)  MGI  Alliance
Rattus norvegicus (Norway rat) : Calcrl (calcitonin receptor like receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Calcrl (calcitonin receptor like receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CALCRL (calcitonin receptor like receptor)
Canis lupus familiaris (dog) : CALCRL (calcitonin receptor like receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Calcrl (calcitonin receptor like receptor)
Sus scrofa (pig) : CALCRL (calcitonin receptor like receptor)
Chlorocebus sabaeus (African green monkey) : CALCRL (calcitonin receptor like receptor)
Heterocephalus glaber (naked mole-rat) : Calcrl (calcitonin receptor like receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2187,341,964 - 187,448,460 (-)Ensembl
GRCh382187,341,964 - 187,448,304 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372188,206,690 - 188,313,021 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362187,916,091 - 188,021,266 (-)NCBINCBI36hg18NCBI36
Build 342188,035,337 - 188,138,484NCBI
Celera2181,804,216 - 181,909,138 (-)NCBI
Cytogenetic Map2q32.1NCBI
HuRef2180,066,508 - 180,172,591 (-)NCBIHuRef
CHM1_12188,212,632 - 188,318,691 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CALCRL
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733108
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.