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Gene: Lgi1 (leucine-rich repeat LGI family, member 1) Mus musculus
Symbol: Lgi1
Name: leucine-rich repeat LGI family, member 1
Description: Involved in neurotransmitter receptor localization to postsynaptic specialization membrane. Localizes to the extracellular space; glutamatergic synapse; and synaptic cleft. Used to study familial temporal lobe epilepsy 1. Human ortholog(s) of this gene implicated in familial temporal lobe epilepsy 1. Is expressed in several structures, including central nervous system; diaphragm; sensory organ; and skeletal musculature. Orthologous to human LGI1 (leucine rich glioma inactivated 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BB130740; leucine-rich glioma-inactivated protein 1; leucine-rich, glioma inactivated 1
Homo sapiens (human) : LGI1 (leucine rich glioma inactivated 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lgi1 (leucine-rich, glioma inactivated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lgi1 (leucine rich glioma inactivated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LGI1 (leucine rich glioma inactivated 1)
Canis lupus familiaris (dog) : LGI1 (leucine rich glioma inactivated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lgi1 (leucine rich glioma inactivated 1)
Sus scrofa (pig) : LGI1 (leucine rich glioma inactivated 1)
more info ...
Related Pseudogenes: Gm3888  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1938,264,536 - 38,312,214 (+)Ensembl
GRCm381938,264,687 - 38,308,939 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371938,339,272 - 38,383,429 (+)NCBIGRCm37mm9NCBIm37
MGSCv361938,329,926 - 38,374,083 (+)NCBImm8
Celera1939,059,488 - 39,103,642 (+)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lgi1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733104
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.