CSPG5 (chondroitin sulfate proteoglycan 5) - Rat Genome Database

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Gene: CSPG5 (chondroitin sulfate proteoglycan 5) Homo sapiens
Analyze
Symbol: CSPG5
Name: chondroitin sulfate proteoglycan 5
RGD ID: 733098
HGNC Page HGNC:2467
Description: Predicted to enable growth factor activity. Predicted to be involved in cytoskeleton organization; glial cell projection elongation; and positive regulation of substrate adhesion-dependent cell spreading. Predicted to act upstream of or within modulation of chemical synaptic transmission. Located in Golgi apparatus and Golgi-associated vesicle membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: acidic leucine-rich EGF-like domain-containing brain protein; chondroitin sulfate proteoglycan 5 (neuroglycan C); MGC44034; neuroglycan C; NGC
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,562,238 - 47,580,240 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,562,238 - 47,580,792 (-)EnsemblGRCh38hg38GRCh38
GRCh37347,603,728 - 47,621,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,578,732 - 47,595,363 (-)NCBINCBI36Build 36hg18NCBI36
Build 34347,578,732 - 47,595,193NCBI
Celera347,545,497 - 47,562,148 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,649,609 - 47,667,613 (-)NCBIHuRef
CHM1_1347,553,635 - 47,571,723 (-)NCBICHM1_1
T2T-CHM13v2.0347,581,316 - 47,599,318 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9950058   PMID:11076863   PMID:12477932   PMID:12885772   PMID:14702039   PMID:15358134   PMID:16299773   PMID:16901907   PMID:19367581   PMID:21873635   PMID:22020285  
PMID:26186194   PMID:27880917   PMID:28514442   PMID:32296183   PMID:32653642   PMID:33961781   PMID:35271311  


Genomics

Comparative Map Data
CSPG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,562,238 - 47,580,240 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,562,238 - 47,580,792 (-)EnsemblGRCh38hg38GRCh38
GRCh37347,603,728 - 47,621,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,578,732 - 47,595,363 (-)NCBINCBI36Build 36hg18NCBI36
Build 34347,578,732 - 47,595,193NCBI
Celera347,545,497 - 47,562,148 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,649,609 - 47,667,613 (-)NCBIHuRef
CHM1_1347,553,635 - 47,571,723 (-)NCBICHM1_1
T2T-CHM13v2.0347,581,316 - 47,599,318 (-)NCBIT2T-CHM13v2.0
Cspg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,072,851 - 110,091,644 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,072,851 - 110,091,644 (+)EnsemblGRCm39 Ensembl
GRCm389110,243,783 - 110,262,576 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,243,783 - 110,262,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,146,287 - 110,165,080 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,090,627 - 110,107,752 (+)NCBIMGSCv36mm8
Celera9109,972,242 - 109,991,159 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.89NCBI
Cspg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,098,932 - 119,113,191 (+)NCBIGRCr8
mRatBN7.28110,220,506 - 110,234,766 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,220,653 - 110,234,758 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,836,168 - 115,850,256 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,035,357 - 114,049,445 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,878,144 - 111,892,232 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,333,695 - 118,348,040 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,333,706 - 118,347,582 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,686,012 - 117,699,639 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,621,534 - 114,635,336 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,640,987 - 114,654,786 (+)NCBI
Celera8109,507,895 - 109,521,130 (+)NCBICelera
Cytogenetic Map8q32NCBI
Cspg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,734,561 - 24,747,414 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,735,155 - 24,746,580 (+)NCBIChiLan1.0ChiLan1.0
CSPG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,520,542 - 47,537,132 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,525,309 - 47,541,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,464,341 - 47,482,910 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,563,837 - 48,579,593 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,564,199 - 48,580,048 (-)Ensemblpanpan1.1panPan2
CSPG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,344,098 - 41,356,810 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,344,093 - 41,356,800 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,259,864 - 41,288,755 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,826,723 - 41,855,158 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,826,723 - 41,839,797 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,068,831 - 41,097,249 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,469,308 - 41,498,069 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,750,035 - 41,778,891 (+)NCBIUU_Cfam_GSD_1.0
Cspg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,686,474 - 201,700,710 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,235,545 - 1,251,166 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,235,550 - 1,251,100 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSPG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,387,224 - 30,411,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,387,225 - 30,404,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,636,335 - 33,642,435 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSPG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,963,493 - 8,982,308 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,963,676 - 8,980,225 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041158,141,489 - 158,160,497 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cspg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,861,847 - 73,873,521 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473073,860,578 - 73,871,515 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CSPG5
34 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001206945.1(CSPG5):c.969-844G>A single nucleotide variant Lung cancer [RCV000093587] Chr3:47570071 [GRCh38]
Chr3:47611561 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001206945.1(CSPG5):c.879C>T (p.Leu293=) single nucleotide variant Malignant melanoma [RCV000066096] Chr3:47572775 [GRCh38]
Chr3:47614265 [GRCh37]
Chr3:47589269 [NCBI36]
Chr3:3p21.31		 not provided
GRCh38/hg38 3p21.31-21.2(chr3:45879883-50749922)x4 copy number gain See cases [RCV000133650] Chr3:45879883..50749922 [GRCh38]
Chr3:45921375..50787353 [GRCh37]
Chr3:45896379..50762357 [NCBI36]
Chr3:3p21.31-21.2		 pathogenic
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31		 likely pathogenic
NM_001206945.1(CSPG5):c.*3_*11delCAGAGCAAG deletion not specified [RCV000485419] Chr3:47562589..47562597 [GRCh38]
Chr3:47604079..47604087 [GRCh37]
Chr3:3p21.31		 likely benign
NM_006574.4(CSPG5):c.40C>A (p.Pro14Thr) single nucleotide variant Inborn genetic diseases [RCV003253141] Chr3:47578654 [GRCh38]
Chr3:47620144 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006574.4(CSPG5):c.1202C>T (p.Thr401Met) single nucleotide variant Inborn genetic diseases [RCV003297895] Chr3:47572866 [GRCh38]
Chr3:47614356 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006574.4(CSPG5):c.378G>T (p.Thr126=) single nucleotide variant not provided [RCV000969177] Chr3:47577648 [GRCh38]
Chr3:47619138 [GRCh37]
Chr3:3p21.31		 benign
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616) copy number gain not provided [RCV000767704] Chr3:45153770..53878616 [GRCh37]
Chr3:3p21.31-21.1		 pathogenic
NM_006574.4(CSPG5):c.763G>A (p.Asp255Asn) single nucleotide variant Inborn genetic diseases [RCV003290482] Chr3:47577263 [GRCh38]
Chr3:47618753 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1232G>A (p.Arg411His) single nucleotide variant Inborn genetic diseases [RCV003272326] Chr3:47572836 [GRCh38]
Chr3:47614326 [GRCh37]
Chr3:3p21.31		 uncertain significance
NC_000003.11:g.(?_45435946)_(49137751_?)dup duplication Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome [RCV003116297] Chr3:45435946..49137751 [GRCh37]
Chr3:3p21.31		 uncertain significance
NC_000003.11:g.(?_47422587)_(47919033_?)dup duplication not provided [RCV003119596] Chr3:47422587..47919033 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p21.31(chr3:44948482-49115809)x1 copy number loss not provided [RCV002279744] Chr3:44948482..49115809 [GRCh37]
Chr3:3p21.31		 pathogenic
NM_006574.4(CSPG5):c.238G>A (p.Gly80Ser) single nucleotide variant Inborn genetic diseases [RCV003012734] Chr3:47577788 [GRCh38]
Chr3:47619278 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1532T>A (p.Ile511Asn) single nucleotide variant Inborn genetic diseases [RCV002882655] Chr3:47562688 [GRCh38]
Chr3:47604178 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.925C>G (p.Leu309Val) single nucleotide variant Inborn genetic diseases [RCV002864434] Chr3:47577101 [GRCh38]
Chr3:47618591 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.837G>C (p.Glu279Asp) single nucleotide variant Inborn genetic diseases [RCV002682853] Chr3:47577189 [GRCh38]
Chr3:47618679 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.116C>G (p.Ala39Gly) single nucleotide variant Inborn genetic diseases [RCV002773450] Chr3:47577910 [GRCh38]
Chr3:47619400 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.477C>G (p.Asp159Glu) single nucleotide variant Inborn genetic diseases [RCV002753545] Chr3:47577549 [GRCh38]
Chr3:47619039 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.667G>T (p.Ala223Ser) single nucleotide variant Inborn genetic diseases [RCV002779080] Chr3:47577359 [GRCh38]
Chr3:47618849 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1205A>C (p.Gln402Pro) single nucleotide variant Inborn genetic diseases [RCV002774597] Chr3:47572863 [GRCh38]
Chr3:47614353 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1373G>A (p.Arg458His) single nucleotide variant Inborn genetic diseases [RCV002692019] Chr3:47572695 [GRCh38]
Chr3:47614185 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.613T>A (p.Ser205Thr) single nucleotide variant Inborn genetic diseases [RCV002691962] Chr3:47577413 [GRCh38]
Chr3:47618903 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.641A>G (p.Glu214Gly) single nucleotide variant Inborn genetic diseases [RCV002884438] Chr3:47577385 [GRCh38]
Chr3:47618875 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.655G>C (p.Glu219Gln) single nucleotide variant Inborn genetic diseases [RCV002985991] Chr3:47577371 [GRCh38]
Chr3:47618861 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.955C>T (p.Arg319Trp) single nucleotide variant Inborn genetic diseases [RCV002763204] Chr3:47577071 [GRCh38]
Chr3:47618561 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.716C>G (p.Pro239Arg) single nucleotide variant Inborn genetic diseases [RCV002891486] Chr3:47577310 [GRCh38]
Chr3:47618800 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1030G>A (p.Gly344Arg) single nucleotide variant Inborn genetic diseases [RCV002849966] Chr3:47576996 [GRCh38]
Chr3:47618486 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1458+46C>T single nucleotide variant Inborn genetic diseases [RCV002699803] Chr3:47569106 [GRCh38]
Chr3:47610596 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.595C>G (p.Leu199Val) single nucleotide variant Inborn genetic diseases [RCV002644728] Chr3:47577431 [GRCh38]
Chr3:47618921 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1372C>T (p.Arg458Cys) single nucleotide variant Inborn genetic diseases [RCV002878281] Chr3:47572696 [GRCh38]
Chr3:47614186 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.732G>C (p.Glu244Asp) single nucleotide variant Inborn genetic diseases [RCV002668936] Chr3:47577294 [GRCh38]
Chr3:47618784 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.289G>C (p.Gly97Arg) single nucleotide variant Inborn genetic diseases [RCV003299097] Chr3:47577737 [GRCh38]
Chr3:47619227 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.491C>T (p.Ala164Val) single nucleotide variant Inborn genetic diseases [RCV003212044] Chr3:47577535 [GRCh38]
Chr3:47619025 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1319C>T (p.Thr440Met) single nucleotide variant Inborn genetic diseases [RCV003185029] Chr3:47572749 [GRCh38]
Chr3:47614239 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.38C>A (p.Pro13Gln) single nucleotide variant Inborn genetic diseases [RCV003375739] Chr3:47578656 [GRCh38]
Chr3:47620146 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.1430C>G (p.Ser477Cys) single nucleotide variant Inborn genetic diseases [RCV003369278] Chr3:47569180 [GRCh38]
Chr3:47610670 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006574.4(CSPG5):c.639C>T (p.Phe213=) single nucleotide variant not provided [RCV003437810] Chr3:47577387 [GRCh38]
Chr3:47618877 [GRCh37]
Chr3:3p21.31		 likely benign
GRCh37/hg19 3p21.31(chr3:47405305-47880799)x3 copy number gain not specified [RCV003986460] Chr3:47405305..47880799 [GRCh37]
Chr3:3p21.31		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR3691hsa-miR-3691-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:832
Count of miRNA genes:477
Interacting mature miRNAs:529
Transcripts:ENST00000264723, ENST00000383738, ENST00000456150, ENST00000465441
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
CSPG5_9165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37347,603,629 - 47,604,190UniSTSGRCh37
Build 36347,578,633 - 47,579,194RGDNCBI36
Celera347,545,398 - 47,545,959RGD
HuRef347,649,510 - 47,650,072UniSTS
D3S4374  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37347,609,575 - 47,609,734UniSTSGRCh37
Build 36347,584,579 - 47,584,738RGDNCBI36
Celera347,551,344 - 47,551,503RGD
HuRef347,655,457 - 47,655,616UniSTS
WI-18411  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37347,603,789 - 47,603,891UniSTSGRCh37
Build 36347,578,793 - 47,578,895RGDNCBI36
Celera347,545,558 - 47,545,660RGD
Cytogenetic Map3p21.3UniSTS
HuRef347,649,670 - 47,649,772UniSTS
GeneMap99-GB4 RH Map3158.23UniSTS
Whitehead-RH Map3185.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 3 4 6 2 1 2 10 13 2594 4 68 59 4
Low 1352 1127 701 92 191 78 2478 640 750 118 765 1097 22 561 1374 1
Below cutoff 1065 1771 970 486 1597 342 1858 1533 364 277 615 448 148 643 1406 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047447332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC112512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF059274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF461087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF461088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF461089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI368601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI989800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW003890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM674119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU732090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB636494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000264723   ⟹   ENSP00000264723
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl347,562,238 - 47,578,865 (-)Ensembl
RefSeq Acc Id: ENST00000383738   ⟹   ENSP00000373244
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl347,562,239 - 47,580,792 (-)Ensembl
RefSeq Acc Id: ENST00000456150   ⟹   ENSP00000392096
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl347,562,239 - 47,578,133 (-)Ensembl
RefSeq Acc Id: ENST00000465441
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl347,577,687 - 47,580,240 (-)Ensembl
RefSeq Acc Id: ENST00000610462   ⟹   ENSP00000478923
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl347,562,247 - 47,578,869 (-)Ensembl
RefSeq Acc Id: NM_001206942   ⟹   NP_001193871
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,580,240 (-)NCBI
GRCh37347,603,728 - 47,621,730 (-)ENTREZGENE
HuRef347,649,609 - 47,667,613 (-)ENTREZGENE
CHM1_1347,553,635 - 47,571,723 (-)NCBI
T2T-CHM13v2.0347,581,316 - 47,599,318 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206943   ⟹   NP_001193872
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,578,865 (-)NCBI
GRCh37347,603,728 - 47,621,730 (-)ENTREZGENE
HuRef347,649,609 - 47,667,613 (-)ENTREZGENE
CHM1_1347,553,635 - 47,570,227 (-)NCBI
T2T-CHM13v2.0347,581,316 - 47,597,943 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206944   ⟹   NP_001193873
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,578,865 (-)NCBI
GRCh37347,603,728 - 47,621,730 (-)ENTREZGENE
HuRef347,649,609 - 47,667,613 (-)ENTREZGENE
CHM1_1347,553,635 - 47,570,227 (-)NCBI
T2T-CHM13v2.0347,581,316 - 47,597,943 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206945   ⟹   NP_001193874
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,580,240 (-)NCBI
GRCh37347,603,728 - 47,621,730 (-)ENTREZGENE
HuRef347,649,609 - 47,667,613 (-)ENTREZGENE
CHM1_1347,553,635 - 47,571,723 (-)NCBI
T2T-CHM13v2.0347,581,316 - 47,599,318 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006574   ⟹   NP_006565
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,578,865 (-)NCBI
GRCh37347,603,728 - 47,621,730 (-)ENTREZGENE
Build 36347,578,732 - 47,595,363 (-)NCBI Archive
Celera347,545,497 - 47,562,148 (-)RGD
HuRef347,649,609 - 47,667,613 (-)ENTREZGENE
CHM1_1347,553,635 - 47,570,227 (-)NCBI
T2T-CHM13v2.0347,581,316 - 47,597,943 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047447332   ⟹   XP_047303288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,562,238 - 47,578,239 (-)NCBI
RefSeq Acc Id: XM_054344989   ⟹   XP_054200964
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0347,581,316 - 47,597,317 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_006565   ⟸   NM_006574
- Peptide Label: isoform 1 precursor
- UniProtKB: O95196 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193871   ⟸   NM_001206942
- Peptide Label: isoform 2
- UniProtKB: B7Z2E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193874   ⟸   NM_001206945
- Peptide Label: isoform 5
- UniProtKB: B7Z2E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193873   ⟸   NM_001206944
- Peptide Label: isoform 4 precursor
- UniProtKB: A0A087WUT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193872   ⟸   NM_001206943
- Peptide Label: isoform 3 precursor
- UniProtKB: Q71M39 (UniProtKB/Swiss-Prot),   Q71M40 (UniProtKB/Swiss-Prot),   O95196 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000478923   ⟸   ENST00000610462
RefSeq Acc Id: ENSP00000392096   ⟸   ENST00000456150
RefSeq Acc Id: ENSP00000264723   ⟸   ENST00000264723
RefSeq Acc Id: ENSP00000373244   ⟸   ENST00000383738
RefSeq Acc Id: XP_047303288   ⟸   XM_047447332
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054200964   ⟸   XM_054344989
- Peptide Label: isoform X1
Protein Domains
CSPG5 sulphate attachment   EGF-like   Neural chondroitin sulphate proteoglycan

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O95196-F1-model_v2 AlphaFold O95196 1-566 view protein structure

Promoters
RGD ID:6864264
Promoter ID:EPDNEW_H5297
Type:initiation region
Name:CSPG5_1
Description:chondroitin sulfate proteoglycan 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38347,578,856 - 47,578,916EPDNEW
RGD ID:6800660
Promoter ID:HG_KWN:44842
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:ENST00000264723,   OTTHUMT00000345351,   UC003CRN.1,   UC003CRP.2
Position:
Human AssemblyChrPosition (strand)Source
Build 36347,594,851 - 47,598,227 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:2467 AgrOrtholog
COSMIC CSPG5 COSMIC
Ensembl Genes ENSG00000114646 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000264723 ENTREZGENE
  ENST00000264723.9 UniProtKB/Swiss-Prot
  ENST00000383738 ENTREZGENE
  ENST00000383738.6 UniProtKB/Swiss-Prot
  ENST00000456150 ENTREZGENE
  ENST00000456150.5 UniProtKB/Swiss-Prot
  ENST00000610462 ENTREZGENE
  ENST00000610462.1 UniProtKB/TrEMBL
GTEx ENSG00000114646 GTEx
HGNC ID HGNC:2467 ENTREZGENE
Human Proteome Map CSPG5 Human Proteome Map
InterPro CSPG5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CSPG5_S_attach_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neural_ProG_Cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10675 UniProtKB/Swiss-Prot
NCBI Gene 10675 ENTREZGENE
OMIM 606775 OMIM
PANTHER CHONDROITIN SULFATE PROTEOGLYCAN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15381 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Chon_Sulph_att UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neural_ProG_Cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26965 PharmGKB
UniProt A0A087WUT8 ENTREZGENE, UniProtKB/TrEMBL
  B7Z2E0 ENTREZGENE, UniProtKB/TrEMBL
  CSPG5_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q71M39 ENTREZGENE
  Q71M40 ENTREZGENE
UniProt Secondary Q71M39 UniProtKB/Swiss-Prot
  Q71M40 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 CSPG5  chondroitin sulfate proteoglycan 5    chondroitin sulfate proteoglycan 5 (neuroglycan C)  Symbol and/or name change 5135510 APPROVED