Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MECR (mitochondrial trans-2-enoyl-CoA reductase) Homo sapiens
Symbol: MECR
Name: mitochondrial trans-2-enoyl-CoA reductase
Description: Exhibits trans-2-enoyl-CoA reductase (NADPH) activity. Involved in fatty acid metabolic process. Localizes to mitochondrion. Implicated in dystonia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2-enoyl thioester reductase; CGI-63; DYTOABG; enoyl-[acyl-carrier-protein] reductase, mitochondrial; ETR1; FASN2B; homolog of yeast 2-enoyl thioester reductase; hsNrbf-1; mitochondrial 2-enoyl thioester reductase; NRBF-1; NRBF1; nuclear receptor binding factor 1; nuclear receptor-binding factor 1; trans-2-enoyl-CoA reductase, mitochondrial
Mus musculus (house mouse) : Mecr (mitochondrial trans-2-enoyl-CoA reductase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mecr (mitochondrial trans-2-enoyl-CoA reductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mecr (mitochondrial trans-2-enoyl-CoA reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : MECR (mitochondrial trans-2-enoyl-CoA reductase)
Canis lupus familiaris (dog) : MECR (mitochondrial trans-2-enoyl-CoA reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mecr (mitochondrial trans-2-enoyl-CoA reductase)
Sus scrofa (pig) : MECR (mitochondrial trans-2-enoyl-CoA reductase)
Chlorocebus sabaeus (African green monkey) : MECR (mitochondrial trans-2-enoyl-CoA reductase)
Heterocephalus glaber (naked mole-rat) : Mecr (mitochondrial trans-2-enoyl-CoA reductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl129,192,657 - 29,230,942 (-)EnsemblGRCh38hg38GRCh38
GRCh38129,192,657 - 29,230,948 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37129,519,385 - 29,557,460 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,391,972 - 29,430,041 (-)NCBINCBI36hg18NCBI36
Build 34129,340,949 - 29,378,060NCBI
Celera127,915,536 - 27,953,607 (-)NCBI
Cytogenetic Map1p35.3NCBI
HuRef127,771,018 - 27,808,772 (-)NCBIHuRef
CHM1_1129,634,568 - 29,672,865 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MECR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733084
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.