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Gene: OPLAH (5-oxoprolinase, ATP-hydrolysing) Homo sapiens
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Symbol: OPLAH
Name: 5-oxoprolinase, ATP-hydrolysing
Description: Predicted to have 5-oxoprolinase (ATP-hydrolyzing) activity. Predicted to be involved in glutathione metabolic process. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-Opase; 5-oxo-L-prolinase; 5-oxoprolinase; 5-oxoprolinase (ATP-hydrolysing); DKFZp434H244; OPLA; OPLAHD; pyroglutamase
Orthologs:
Mus musculus (house mouse) : Oplah (5-oxoprolinase (ATP-hydrolysing))  MGI  Alliance
Rattus norvegicus (Norway rat) : Oplah (5-oxoprolinase (ATP-hydrolysing))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oplah (5-oxoprolinase, ATP-hydrolysing)
Pan paniscus (bonobo/pygmy chimpanzee) : OPLAH (5-oxoprolinase, ATP-hydrolysing)
Canis lupus familiaris (dog) : OPLAH (5-oxoprolinase, ATP-hydrolysing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oplah (5-oxoprolinase, ATP-hydrolysing)
Sus scrofa (pig) : OPLAH (5-oxoprolinase, ATP-hydrolysing)
Chlorocebus sabaeus (green monkey) : OPLAH (5-oxoprolinase, ATP-hydrolysing)
Heterocephalus glaber (naked mole-rat) : Oplah (5-oxoprolinase, ATP-hydrolysing)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8144,051,266 - 144,063,965 (-)Ensembl
GRCh388144,051,266 - 144,064,026 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378145,106,167 - 145,115,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,178,155 - 145,186,959 (-)NCBINCBI36hg18NCBI36
Build 348145,178,164 - 145,186,923NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,381,985 - 140,391,401 (-)NCBIHuRef
CHM1_18145,146,427 - 145,155,865 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on OPLAH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733077
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.