Gene: KCNC3 (potassium voltage-gated channel subfamily C member 3) Homo sapiens
Symbol: KCNC3
Name: potassium voltage-gated channel subfamily C member 3
Description: The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KSHIIID; KV3.3; OTTHUMP00000042078; OTTHUMP00000232123; potassium channel, voltage gated Shaw related subfamily C, member 3; potassium voltage-gated channel, Shaw-related subfamily, member 3; SCA13; Shaw-related voltage-gated potassium channel protein 3; spinocerebellar ataxia 13; voltage-gated potassium channel protein KV3.3; voltage-gated potassium channel subunit Kv3.3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381950,311,942 - 50,333,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371950,818,765 - 50,832,634 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,510,577 - 55,524,446 (-)NCBINCBI36hg18NCBI36
Build 341955,510,576 - 55,524,446NCBI
Celera1947,869,096 - 47,882,964 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1947,156,998 - 47,170,888 (-)NCBIHuRef
CHM1_11950,817,013 - 50,838,555 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
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Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733063
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-02-19
Status: ACTIVE