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Gene: Cldn16 (claudin 16) Mus musculus
Symbol: Cldn16
Name: claudin 16
Description: Predicted to have structural molecule activity. Predicted to be involved in several processes, including bicellular tight junction assembly; positive regulation of calcium ion transport; and transepithelial transport. Localizes to bicellular tight junction. Is expressed in metanephros. Used to study renal hypomagnesemia 3. Human ortholog(s) of this gene implicated in renal hypomagnesemia 3 and renal tubular transport disease. Orthologous to human CLDN16 (claudin 16).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: claudin-16; H59D2a protein; paracellin-1; PCLN1
Homo sapiens (human) : CLDN16 (claudin 16)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cldn16 (claudin 16)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn16 (claudin 16)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN16 (claudin 16)
Canis lupus familiaris (dog) : CLDN16 (claudin 16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn16 (claudin 16)
Sus scrofa (pig) : CLDN16 (claudin 16)
Chlorocebus sabaeus (African green monkey) : CLDN16 (claudin 16)
Heterocephalus glaber (naked mole-rat) : Cldn16 (claudin 16)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1626,463,135 - 26,482,765 (+)EnsemblGRCm38mm10GRCm38
GRCm381626,463,135 - 26,482,765 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371626,463,246 - 26,482,853 (+)NCBIGRCm37mm9NCBIm37
MGSCv361626,378,509 - 26,398,125 (+)NCBImm8
Celera1627,006,449 - 27,026,198 (+)NCBICelera
Cytogenetic Map16B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cldn16
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733040
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.