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Gene: CLCN5 (chloride voltage-gated channel 5) Homo sapiens
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Symbol: CLCN5
Name: chloride voltage-gated channel 5
Description: Exhibits identical protein binding activity. Predicted to be involved in excretion and ion transmembrane transport. Localizes to several cellular components, including the Golgi apparatus; apical part of cell; and cytosol. Implicated in Dent disease and X-linked recessive hypophosphatemic rickets.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel 5; chloride channel protein 5; chloride channel, voltage-sensitive 5; chloride transporter ClC-5; clC-5; CLC5; CLCK2; DENTS; H(+)/Cl(-) exchange transporter 5; hCIC-K2; hClC-K2; nephrolithiasis 1 (X-linked); NPHL1; NPHL2; voltage-gated chloride ion channel CLCN5; XLRH; XRN
Orthologs:
Mus musculus (house mouse) : Clcn5 (chloride channel, voltage-sensitive 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clcn5 (chloride voltage-gated channel 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn5 (chloride voltage-gated channel 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN5 (chloride voltage-gated channel 5)
Canis lupus familiaris (dog) : CLCN5 (chloride voltage-gated channel 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn5 (chloride voltage-gated channel 5)
Sus scrofa (pig) : CLCN5 (chloride voltage-gated channel 5)
Chlorocebus sabaeus (African green monkey) : CLCN5 (chloride voltage-gated channel 5)
Heterocephalus glaber (naked mole-rat) : Clcn5 (chloride voltage-gated channel 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX49,922,596 - 50,099,235 (+)Ensembl
GRCh38X49,922,596 - 50,099,235 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,687,225 - 49,863,892 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,718,955 - 49,750,632 (+)NCBINCBI36hg18NCBI36
Build 34X49,537,191 - 49,560,557NCBI
CeleraX53,756,528 - 53,932,992 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX47,156,646 - 47,337,277 (+)NCBIHuRef
CHM1_1X49,766,989 - 49,943,526 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CLCN5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733029
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.