Tpp1 (tripeptidyl peptidase I) - Rat Genome Database

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Gene: Tpp1 (tripeptidyl peptidase I) Mus musculus
Analyze
Symbol: Tpp1
Name: tripeptidyl peptidase I
RGD ID: 732982
MGI Page MGI
Description: Enables tripeptidyl-peptidase activity. Acts upstream of or within lysosomal protein catabolic process; lysosome organization; and neuromuscular process controlling balance. Located in lysosome. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Used to study neuronal ceroid lipofuscinosis 2. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 7 and neuronal ceroid lipofuscinosis 2. Orthologous to human TPP1 (tripeptidyl peptidase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ceroid-lipofuscinosis, neuronal 2; Cl; Cln2; LPIC; lysosomal pepstatin-insensitive protease; TPP-1; TPP-I; tripeptidyl aminopeptidase; tripeptidyl peptidase-I; tripeptidyl-peptidase 1; tripeptidyl-peptidase I
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,394,018 - 105,401,489 (-)NCBIGRCm39mm39
GRCm39 Ensembl7105,394,018 - 105,401,442 (-)Ensembl
GRCm387105,744,811 - 105,752,282 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,744,811 - 105,752,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,893,361 - 112,900,721 (-)NCBIGRCm37mm9NCBIm37
MGSCv367105,618,668 - 105,626,028 (-)NCBImm8
Celera7106,016,147 - 106,023,505 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-tert-Octylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
alpha,alpha-trehalose  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenamidone  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fumonisin B1  (EXP)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosomorpholine  (ISO)
nickel atom  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
pirimiphos-methyl  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
Propiverine  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
Yessotoxin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:9989590   PMID:10330339   PMID:10349636   PMID:10527801   PMID:10556422   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11423996   PMID:12038963   PMID:12466851  
PMID:12477932   PMID:14609438   PMID:14651853   PMID:15158442   PMID:15483130   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16170054   PMID:16602821   PMID:17053789  
PMID:17110338   PMID:17948054   PMID:18343701   PMID:18570628   PMID:18639872   PMID:19429009   PMID:19749771   PMID:19941651   PMID:19995905   PMID:20231318   PMID:20493811   PMID:21267068  
PMID:21873635   PMID:21996941   PMID:22099311   PMID:22101936   PMID:22792360   PMID:22989886   PMID:23804102   PMID:25056954   PMID:25303899   PMID:25917818   PMID:26778124   PMID:27101989  
PMID:28464005   PMID:28728022   PMID:29408933   PMID:30022158   PMID:30928643   PMID:32325033  


Genomics

Comparative Map Data
Tpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,394,018 - 105,401,489 (-)NCBIGRCm39mm39
GRCm39 Ensembl7105,394,018 - 105,401,442 (-)Ensembl
GRCm387105,744,811 - 105,752,282 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,744,811 - 105,752,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,893,361 - 112,900,721 (-)NCBIGRCm37mm9NCBIm37
MGSCv367105,618,668 - 105,626,028 (-)NCBImm8
Celera7106,016,147 - 106,023,505 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.97NCBI
TPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl116,612,768 - 6,619,448 (-)EnsemblGRCh38hg38GRCh38
GRCh38116,612,768 - 6,619,422 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,633,999 - 6,640,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,590,573 - 6,597,268 (-)NCBINCBI36hg18NCBI36
Celera116,753,063 - 6,759,757 (-)NCBI
Cytogenetic Map11p15.4NCBI
HuRef116,292,929 - 6,299,623 (-)NCBIHuRef
CHM1_1116,632,898 - 6,639,593 (-)NCBICHM1_1
Tpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21160,097,984 - 160,104,108 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1170,588,035 - 170,594,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01170,588,036 - 170,594,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01177,592,725 - 177,600,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,490,394 - 163,496,517 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11163,585,870 - 163,591,994 (-)NCBI
Celera1158,029,903 - 158,035,938 (-)NCBICelera
Cytogenetic Map1q32NCBI
Tpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,324,856 - 22,330,912 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,324,847 - 22,330,912 (-)NCBIChiLan1.0ChiLan1.0
TPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1116,427,516 - 6,434,222 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,427,522 - 6,434,222 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0116,744,815 - 6,751,556 (-)NCBIMhudiblu_PPA_v0panPan3
TPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,921,764 - 29,926,974 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,921,764 - 29,926,986 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,623,623 - 29,628,832 (-)NCBI
ROS_Cfam_1.02130,747,948 - 30,753,157 (-)NCBI
UMICH_Zoey_3.12130,068,707 - 30,073,915 (-)NCBI
UNSW_CanFamBas_1.02130,234,365 - 30,239,567 (-)NCBI
UU_Cfam_GSD_1.02130,429,691 - 30,434,901 (-)NCBI
Tpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494755,998,722 - 56,005,618 (+)NCBI
SpeTri2.0NW_004936842669,869 - 676,706 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl93,135,642 - 3,143,408 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.193,135,580 - 3,143,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,792,812 - 3,800,637 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,205,999 - 58,211,743 (+)NCBI
ChlSab1.1 Ensembl158,206,072 - 58,210,945 (+)Ensembl
Vero_WHO_p1.0NW_023666038156,031,787 - 156,038,501 (+)NCBI
Tpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248178,104,934 - 8,111,049 (-)NCBI

Position Markers
AI414982  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,753,064 - 105,753,190UniSTSGRCm38
MGSCv377112,901,578 - 112,901,704UniSTSGRCm37
Celera7106,024,417 - 106,024,543UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS
Whitehead/MRC_RH71049.55UniSTS
Whitehead/MRC_RH71066.06UniSTS
AW107731  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,746,267 - 105,746,460UniSTSGRCm38
MGSCv377112,894,781 - 112,894,974UniSTSGRCm37
Celera7106,017,567 - 106,017,760UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS
Whitehead/MRC_RH71059.88UniSTS
Tpp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,749,939 - 105,750,219UniSTSGRCm38
MGSCv377112,898,453 - 112,898,733UniSTSGRCm37
Celera7106,021,237 - 106,021,517UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS
D1Bda72  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,749,683 - 105,750,228UniSTSGRCm38
MGSCv377112,898,197 - 112,898,742UniSTSGRCm37
Celera7106,020,981 - 106,021,526UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS
D7Mit95  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,751,411 - 105,751,503UniSTSGRCm38
MGSCv377112,899,925 - 112,900,017UniSTSGRCm37
Celera7106,022,709 - 106,022,801UniSTS
Cytogenetic Map7E3UniSTS
cM Map751.0UniSTS
Whitehead Genetic737.2UniSTS
PCDH16_1801  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,752,996 - 105,753,877UniSTSGRCm38
MGSCv377112,901,510 - 112,902,391UniSTSGRCm37
Celera7106,024,349 - 106,025,230UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS
Cln2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,751,131 - 105,751,549UniSTSGRCm38
MGSCv377112,899,645 - 112,900,063UniSTSGRCm37
Celera7106,022,429 - 106,022,847UniSTS
Cytogenetic Map7E3UniSTS
cM Map750.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730500000109400000Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736580590116817642Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745512542119094307Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)755169841117223580Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)768200000105800000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772614164106614164Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)774076757108076757Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775745007109745138Mouse
14746989Manh62_mmandible shape 62 (mouse)776093321110093321Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80902474114902584Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780902474114902584Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)781200000127100000Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781600000124600000Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781800000126900000Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)782200000126900000Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785400000124600000Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785716387112934612Mouse
1301647Elpt_melevated leptin (mouse)Not determined786850979120851122Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787394725121394859Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787394725121394859Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787394725121394859Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787493929119886157Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787600000126900000Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787600000126900000Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)788200000108500000Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791883789125883949Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791883789125883949Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793792641127792834Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798565687132565775Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798795739132795739Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined7100238481134238481Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7101151499135151620Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7101394038135394119Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7102094158136094307Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7102094158136094307Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7102094158136094307Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102885996136886157Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105651440139651588Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105750785139750785Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:757
Count of miRNA genes:428
Interacting mature miRNAs:514
Transcripts:ENSMUST00000033184
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA499658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC121823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF111172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF124599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ011912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000033184   ⟹   ENSMUSP00000033184
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,744,811 - 105,752,235 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210018
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,746,946 - 105,749,132 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210066   ⟹   ENSMUSP00000147729
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,749,256 - 105,752,217 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210395
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,749,578 - 105,752,198 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210730
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,749,374 - 105,752,095 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,745,919 - 105,752,213 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211204
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,750,272 - 105,752,196 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211226
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,749,944 - 105,752,215 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211560
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,750,273 - 105,752,196 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211659
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7105,749,682 - 105,752,092 (-)Ensembl
RefSeq Acc Id: NM_009906   ⟹   NP_034036
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,394,018 - 105,401,442 (-)NCBI
GRCm387105,744,811 - 105,752,235 (-)NCBI
MGSCv377112,893,361 - 112,900,721 (-)RGD
Celera7106,016,147 - 106,023,505 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011241668   ⟹   XP_011239970
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,396,387 - 105,401,489 (-)NCBI
GRCm387105,747,174 - 105,752,282 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034036   ⟸   NM_009906
- Peptide Label: preproprotein
- UniProtKB: O89023 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011239970   ⟸   XM_011241668
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000033184   ⟸   ENSMUST00000033184
RefSeq Acc Id: ENSMUSP00000147729   ⟸   ENSMUST00000210066
Protein Domains
Peptidase S53

Promoters
RGD ID:8665137
Promoter ID:EPDNEW_M10600
Type:initiation region
Name:Tpp1_1
Description:Mus musculus tripeptidyl peptidase I , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387105,752,216 - 105,752,276EPDNEW
RGD ID:6842234
Promoter ID:MM_KWN:52108
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000033184
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367112,900,296 - 112,900,796 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1336194 AgrOrtholog
Ensembl Genes ENSMUSG00000030894 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000033184 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000147729 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033184 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000210066 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Peptidase_S8/S53_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8/S53_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S53_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sedolisin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12751 UniProtKB/Swiss-Prot
MGD MGI:1336194 ENTREZGENE
NCBI Gene 12751 ENTREZGENE
Pfam Peptidase_S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pro-kuma_activ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tpp1 PhenoGen
PROSITE SEDOLISIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Pro-kuma_activ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52743 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GRZ6_MOUSE UniProtKB/TrEMBL
  O89023 ENTREZGENE
  Q3TDY6_MOUSE UniProtKB/TrEMBL
  Q3U2Z6_MOUSE UniProtKB/TrEMBL
  TPP1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q543Q8 UniProtKB/Swiss-Prot
  Q9QUS7 UniProtKB/Swiss-Prot