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Gene: Rapgef3 (Rap guanine nucleotide exchange factor (GEF) 3) Mus musculus
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Symbol: Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Description: Exhibits guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including positive regulation of cellular component organization; positive regulation of nitrogen compound metabolic process; and positive regulation of transport. Predicted to colocalize with cortical actin cytoskeleton and plasma membrane. Is expressed in brain; heart; lung; and metanephros. Orthologous to human RAPGEF3 (Rap guanine nucleotide exchange factor 3); PARTICIPATES IN adenosine signaling pathway; long term potentiation; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310016P22Rik; 9330170P05Rik; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; Epac; Epac1; exchange protein directly activated by cAMP 1; MGC19192; rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
Orthologs:
Homo sapiens (human) : RAPGEF3 (Rap guanine nucleotide exchange factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rapgef3 (Rap guanine nucleotide exchange factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rapgef3 (Rap guanine nucleotide exchange factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RAPGEF3 (Rap guanine nucleotide exchange factor 3)
Canis lupus familiaris (dog) : RAPGEF3 (Rap guanine nucleotide exchange factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rapgef3 (Rap guanine nucleotide exchange factor 3)
Sus scrofa (pig) : RAPGEF3 (Rap guanine nucleotide exchange factor 3)
Chlorocebus sabaeus (African green monkey) : RAPGEF3 (Rap guanine nucleotide exchange factor 3)
Heterocephalus glaber (naked mole-rat) : Rapgef3 (Rap guanine nucleotide exchange factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1597,744,770 - 97,767,972 (-)EnsemblGRCm38mm10GRCm38
GRCm381597,744,770 - 97,768,419 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371597,575,201 - 97,598,097 (-)NCBIGRCm37mm9NCBIm37
MGSCv361597,572,987 - 97,595,706 (-)NCBImm8
Celera1599,871,753 - 99,894,632 (-)NCBICelera
Cytogenetic Map15F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rapgef3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732974
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.