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Gene: Slc6a5 (solute carrier family 6 (neurotransmitter transporter, glycine), member 5) Mus musculus
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Symbol: Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Description: Predicted to have glycine:sodium symporter activity. Involved in neurotransmitter reuptake. Localizes to glycinergic synapse. Is expressed in several structures, including adrenal gland; central nervous system; esophagus; lens; and male reproductive gland or organ. Used to study hyperekplexia 3. Human ortholog(s) of this gene implicated in hyperekplexia 3. Orthologous to human SLC6A5 (solute carrier family 6 member 5); INTERACTS WITH 17alpha-ethynylestradiol (ortholog); 6-propyl-2-thiouracil (ortholog); ammonium chloride (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glycine transporter 2; glyT-2; Glyt2; prestin; sodium- and chloride-dependent glycine transporter 2; solute carrier family 6 member 5
Orthologs:
Homo sapiens (human) : SLC6A5 (solute carrier family 6 member 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc6a5 (solute carrier family 6 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a5 (solute carrier family 6 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC6A5 (solute carrier family 6 member 5)
Canis lupus familiaris (dog) : SLC6A5 (solute carrier family 6 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a5 (solute carrier family 6 member 5)
Sus scrofa (pig) : SLC6A5 (solute carrier family 6 member 5)
Chlorocebus sabaeus (African green monkey) : SLC6A5 (solute carrier family 6 member 5)
Heterocephalus glaber (naked mole-rat) : Slc6a5 (solute carrier family 6 member 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl749,910,146 - 49,963,856 (+)EnsemblGRCm38mm10GRCm38
GRCm38749,906,984 - 49,963,864 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37757,165,669 - 57,214,863 (+)NCBIGRCm37mm9NCBIm37
MGSCv36749,778,790 - 49,831,883 (+)NCBImm8
MGSCv36739,534,119 - 39,587,298 (+)NCBImm8
Celera745,360,416 - 45,409,800 (+)NCBICelera
Cytogenetic Map7B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc6a5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732916
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.