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Gene: SLC6A5 (solute carrier family 6 member 5) Homo sapiens
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Symbol: SLC6A5
Name: solute carrier family 6 member 5
Description: Exhibits glycine:sodium symporter activity. Involved in glycine import across plasma membrane and glycinergic synaptic transmission. Localizes to plasma membrane. Implicated in hyperekplexia 3.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glycine transporter 2; GLYT-2; GLYT2; HKPX3; NET1; sodium- and chloride-dependent glycine transporter 2; solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Orthologs:
Mus musculus (house mouse) : Slc6a5 (solute carrier family 6 (neurotransmitter transporter, glycine), member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc6a5 (solute carrier family 6 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a5 (solute carrier family 6 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC6A5 (solute carrier family 6 member 5)
Canis lupus familiaris (dog) : SLC6A5 (solute carrier family 6 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a5 (solute carrier family 6 member 5)
Sus scrofa (pig) : SLC6A5 (solute carrier family 6 member 5)
Chlorocebus sabaeus (African green monkey) : SLC6A5 (solute carrier family 6 member 5)
Heterocephalus glaber (naked mole-rat) : Slc6a5 (solute carrier family 6 member 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1120,599,400 - 20,659,285 (+)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl1120,599,594 - 20,659,285 (+)EnsemblGRCh38hg38GRCh38
GRCh381120,599,494 - 20,659,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371120,620,946 - 20,676,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,577,522 - 20,633,186 (+)NCBINCBI36hg18NCBI36
Build 341120,577,526 - 20,633,039NCBI
Celera1120,753,868 - 20,809,521 (+)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1120,304,109 - 20,359,891 (+)NCBIHuRef
CHM1_11120,620,950 - 20,676,570 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC6A5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732915
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.