Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:24763279 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4,6-tribromophenol | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4-dinitrotoluene | affects expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of PRPSAP2 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of PRPSAP2 mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | tetrabromobisphenol A results in increased expression of PRPSAP2 mRNA | CTD | PMID:27914987 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of PRPSAP2 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of PRPSAP2 protein | CTD | PMID:34186270 | ammonium chloride | affects expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PRPSAP2 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PRPSAP2 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PRPSAP2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PRPSAP2 protein | CTD | PMID:31675489 | bisphenol A | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRPSAP2 gene | CTD | PMID:31601247 | bisphenol F | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:28628672 | caffeine | decreases phosphorylation | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PRPSAP2 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of PRPSAP2 mRNA | CTD | PMID:25554681 | cisplatin | increases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of PRPSAP2 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PRPSAP2 mRNA | CTD | PMID:19549813 | decabromodiphenyl ether | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of PRPSAP2 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PRPSAP2 mRNA | CTD | PMID:17361019 and PMID:21266533 | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of PRPSAP2 mRNA | CTD | PMID:24205000 | enzyme inhibitor | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PRPSAP2 protein | CTD | PMID:23301498 | finasteride | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of PRPSAP2 mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of PRPSAP2 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | PRPSAP2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of PRPSAP2 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRPSAP2 gene | CTD | PMID:31601247 | gentamycin | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PRPSAP2 mRNA | CTD | PMID:22061828 | indometacin | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PRPSAP2 protein | CTD | PMID:32959892 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of PRPSAP2 mRNA | CTD | PMID:21829687 | ozone | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of PRPSAP2 mRNA | CTD | PMID:35430440 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PRPSAP2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of PRPSAP2 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PRPSAP2 mRNA | CTD | PMID:22230336 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PRPSAP2 mRNA | CTD | PMID:23811191 | potassium chromate | decreases expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PRPSAP2 mRNA | CTD | PMID:22079256 | resveratrol | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PRPSAP2 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | PRPSAP2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of PRPSAP2 protein | CTD | PMID:37664457 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of PRPSAP2 mRNA | CTD | PMID:27862939 | Soman | decreases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of PRPSAP2 mRNA | CTD | PMID:19281266 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of PRPSAP2 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | PRPSAP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PRPSAP2 mRNA | CTD | PMID:25979313 | zinc atom | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Zinc results in increased expression of PRPSAP2 mRNA | CTD | PMID:17074742 | zinc sulfate | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Zinc Sulfate results in increased expression of PRPSAP2 mRNA | CTD | PMID:17074742 | zinc(0) | increases expression | ISO | Prpsap2 (Rattus norvegicus) | 6480464 | Zinc results in increased expression of PRPSAP2 mRNA | CTD | PMID:17074742 | |