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Gene: Fbxo2 (F-box protein 2) Mus musculus
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Symbol: Fbxo2
Name: F-box protein 2
Description: Exhibits amyloid-beta binding activity and carbohydrate binding activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in protein catabolic process; protein ubiquitination; and regulation of protein ubiquitination. Localizes to the SCF ubiquitin ligase complex; cytosol; and dendritic spine. Is expressed in brain; testis; and vestibulo-cochlear ganglion. Orthologous to human FBXO2 (F-box protein 2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: F-box only protein 2; FBG1; Fbs1; Fbs2; FBX2; MGC54895; NFB42; prion protein ligand 4; Prpl4
Orthologs:
Homo sapiens (human) : FBXO2 (F-box protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo2 (F-box protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo2 (F-box protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO2 (F-box protein 2)
Canis lupus familiaris (dog) : FBXO2 (F-box protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo2 (F-box protein 2)
Sus scrofa (pig) : FBXO2 (F-box protein 2)
Chlorocebus sabaeus (African green monkey) : FBXO2 (F-box protein 2)
Heterocephalus glaber (naked mole-rat) : Fbxo2 (F-box protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4148,160,621 - 148,166,424 (+)EnsemblGRCm38mm10GRCm38
GRCm384148,160,198 - 148,166,420 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374147,534,777 - 147,540,526 (+)NCBIGRCm37mm9NCBIm37
MGSCv364147,004,468 - 147,010,217 (+)NCBImm8
Celera4150,422,125 - 150,427,887 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxo2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732901
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.