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Gene: AKAP4 (A-kinase anchoring protein 4) Homo sapiens
Symbol: AKAP4
Name: A-kinase anchoring protein 4
Description: Predicted to have protein kinase A binding activity. Involved in flagellated sperm motility. Localizes to the motile cilium.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 75 kda fibrous sheath protein; A kinase (PRKA) anchor protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 82; AKAP-4; AKAP82; cancer/testis antigen 99; CT99; FSC1; hAKAP82; HI; major sperm fibrous sheath protein; p82; PRKA4; protein kinase A anchoring protein 4; protein kinase A-anchoring protein 4; testis-specific gene HI
Mus musculus (house mouse) : Akap4 (A kinase (PRKA) anchor protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Akap4 (A-kinase anchoring protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap4 (A-kinase anchoring protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP4 (A-kinase anchoring protein 4)
Canis lupus familiaris (dog) : AKAP4 (A-kinase anchoring protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap4 (A-kinase anchoring protein 4)
Sus scrofa (pig) : AKAP4 (A-kinase anchoring protein 4)
Chlorocebus sabaeus (African green monkey) : AKAP4 (A-kinase anchoring protein 4)
Heterocephalus glaber (naked mole-rat) : Akap4 (A-kinase anchoring protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX50,190,777 - 50,201,007 (-)Ensembl
GRCh38X50,190,777 - 50,201,007 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,955,411 - 49,965,664 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,842,151 - 49,852,404 (-)NCBINCBI36hg18NCBI36
Build 34X49,658,457 - 49,668,040NCBI
CeleraX54,024,511 - 54,034,765 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX47,427,699 - 47,437,860 (-)NCBIHuRef
CHM1_1X50,035,048 - 50,045,361 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AKAP4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732830
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.