Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Slc12a2 (solute carrier family 12, member 2) Mus musculus
Analyze
Symbol: Slc12a2
Name: solute carrier family 12, member 2
Description: Exhibits potassium ion transmembrane transporter activity. Involved in several processes, including cellular ion homeostasis; inorganic ion import across plasma membrane; and mammary gland duct morphogenesis. Localizes to several cellular components, including apical plasma membrane; basolateral plasma membrane; and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; lung; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in middle cerebral artery infarction. Orthologous to human SLC12A2 (solute carrier family 12 member 2); INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9330166H04Rik; basolateral Na-K-Cl symporter; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; mBSC2; Nkcc1; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 member 2; sy-ns
Orthologs:
Homo sapiens (human) : SLC12A2 (solute carrier family 12 member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc12a2 (solute carrier family 12 member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc12a2 (solute carrier family 12 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC12A2 (solute carrier family 12 member 2)
Canis lupus familiaris (dog) : SLC12A2 (solute carrier family 12 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc12a2 (solute carrier family 12 member 2)
Sus scrofa (pig) : SLC12A2 (solute carrier family 12 member 2)
Chlorocebus sabaeus (African green monkey) : SLC12A2 (solute carrier family 12 member 2)
Heterocephalus glaber (naked mole-rat) : Slc12a2 (solute carrier family 12 member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1857,878,678 - 57,946,821 (+)EnsemblGRCm38mm10GRCm38
GRCm381857,878,512 - 57,946,821 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371858,038,332 - 58,106,475 (+)NCBIGRCm37mm9NCBIm37
MGSCv361858,004,047 - 58,072,174 (+)NCBImm8
Celera1859,157,060 - 59,258,313 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1832.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc12a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732817
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.