Xylt1 (xylosyltransferase 1) - Rat Genome Database

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Gene: Xylt1 (xylosyltransferase 1) Mus musculus
Analyze
Symbol: Xylt1
Name: xylosyltransferase 1
RGD ID: 732773
MGI Page MGI
Description: Exhibits protein xylosyltransferase activity. Involved in cellular response to heat; chondroitin sulfate biosynthetic process; and skeletal system development. Localizes to Golgi cis cisterna. Is expressed in lens. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Orthologous to human XYLT1 (xylosyltransferase 1); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; heparan sulfate biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8030490L12; peptide O-xylosyltransferase 1; xylosyltransferase I
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397116,980,214 - 117,266,853 (+)NCBIGRCm39mm39
GRCm39 Ensembl7116,980,214 - 117,272,803 (+)Ensembl
GRCm387117,380,979 - 117,667,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7117,380,979 - 117,673,580 (+)EnsemblGRCm38mm10GRCm38
MGSCv377124,524,493 - 124,811,144 (+)NCBIGRCm37mm9NCBIm37
MGSCv367117,172,128 - 117,458,779 (+)NCBImm8
MGSCv367107,018,054 - 107,306,726 (+)NCBImm8
Celera7117,414,249 - 117,605,639 (+)NCBICelera
Cytogenetic Map7F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11812828   PMID:15461586   PMID:16141072   PMID:16141073   PMID:17189266   PMID:18755693   PMID:19666503   PMID:21873635  
PMID:24161523   PMID:26414444   PMID:30550785   PMID:32325033  


Genomics

Comparative Map Data
Xylt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397116,980,214 - 117,266,853 (+)NCBIGRCm39mm39
GRCm39 Ensembl7116,980,214 - 117,272,803 (+)Ensembl
GRCm387117,380,979 - 117,667,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7117,380,979 - 117,673,580 (+)EnsemblGRCm38mm10GRCm38
MGSCv377124,524,493 - 124,811,144 (+)NCBIGRCm37mm9NCBIm37
MGSCv367117,172,128 - 117,458,779 (+)NCBImm8
MGSCv367107,018,054 - 107,306,726 (+)NCBImm8
Celera7117,414,249 - 117,605,639 (+)NCBICelera
Cytogenetic Map7F1NCBI
XYLT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1617,101,769 - 17,470,960 (-)EnsemblGRCh38hg38GRCh38
GRCh381617,101,769 - 17,470,960 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371617,195,626 - 17,564,817 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361617,103,682 - 17,472,239 (-)NCBINCBI36hg18NCBI36
Build 341617,108,839 - 17,472,239NCBI
Celera1616,738,145 - 17,106,289 (-)NCBI
Cytogenetic Map16p12.3NCBI
HuRef1616,198,445 - 16,453,510 (-)NCBIHuRef
CHM1_11617,283,444 - 17,652,050 (-)NCBICHM1_1
Xylt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21171,643,925 - 171,929,774 (+)NCBI
Rnor_6.0 Ensembl1187,149,453 - 187,261,632 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01186,939,698 - 187,264,758 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01193,935,737 - 194,218,543 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41175,673,299 - 175,802,134 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11175,826,610 - 175,941,380 (+)NCBI
Celera1169,443,427 - 169,724,035 (+)NCBICelera
Cytogenetic Map1q35NCBI
Xylt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554421,745,924 - 2,036,340 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554421,787,338 - 2,042,523 (+)NCBIChiLan1.0ChiLan1.0
XYLT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11617,216,072 - 17,480,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1617,222,447 - 17,470,818 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01620,078,904 - 20,447,268 (-)NCBIMhudiblu_PPA_v0panPan3
XYLT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1626,742,853 - 27,041,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl626,742,853 - 27,041,666 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha628,109,084 - 28,409,448 (-)NCBI
ROS_Cfam_1.0626,902,243 - 27,205,813 (-)NCBI
UMICH_Zoey_3.1626,702,907 - 27,003,220 (-)NCBI
UNSW_CanFamBas_1.0626,598,683 - 26,899,086 (-)NCBI
UU_Cfam_GSD_1.0626,993,079 - 27,297,436 (-)NCBI
Xylt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344116,089,001 - 116,250,901 (+)NCBI
SpeTri2.0NW_0049365014,164,714 - 4,337,604 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XYLT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl327,158,874 - 27,492,892 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1327,158,438 - 27,492,629 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2327,756,168 - 27,960,491 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XYLT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1516,197,982 - 16,566,893 (+)NCBI
Vero_WHO_p1.0NW_02366606813,399,882 - 13,778,851 (-)NCBI
Xylt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247821,462,888 - 1,763,267 (+)NCBI

Position Markers
Xylt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387117,667,419 - 117,667,588UniSTSGRCm38
MGSCv377124,810,933 - 124,811,102UniSTSGRCm37
Celera7117,605,428 - 117,605,597UniSTS
Cytogenetic Map7F2UniSTS
cM Map7 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745512542119094307Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)781200000127100000Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781600000124600000Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781800000126900000Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)782200000126900000Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785400000124600000Mouse
1301647Elpt_melevated leptin (mouse)Not determined786850979120851122Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787394725121394859Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787394725121394859Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787394725121394859Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787493929119886157Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787600000126900000Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787600000126900000Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791883789125883949Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791883789125883949Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793792641127792834Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798565687132565775Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798795739132795739Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined7100238481134238481Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7101151499135151620Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7101394038135394119Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7102094158136094307Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7102094158136094307Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7102094158136094307Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102885996136886157Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105651440139651588Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105750785139750785Mouse
4141056Lskcn2_mLSK cell number 2 (mouse)Not determined108883789119094307Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7110108163144108163Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7110108163144108163Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7110108163144108163Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7111365511145365612Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7111365511145365612Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111564398145441459Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111564398145441459Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111564398145441459Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112950524145441459Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7113321003145441459Mouse
38501072Stsl7_mSalmonella typhimurium susceptibility locus 7 (mouse)7116100000128900000Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7117032360145441459Mouse
15092059Wogrme1_mweek one growth rate, maternal effect 1 (mouse)7117600000134500000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:365
Count of miRNA genes:274
Interacting mature miRNAs:301
Transcripts:ENSMUST00000032892, ENSMUST00000160035, ENSMUST00000161889
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000032892   ⟹   ENSMUSP00000032892
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7117,380,979 - 117,673,580 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160035
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7117,380,979 - 117,635,185 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161889
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7117,475,492 - 117,549,359 (+)Ensembl
RefSeq Acc Id: NM_175645   ⟹   NP_783576
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397116,980,214 - 117,266,853 (+)NCBI
GRCm387117,380,979 - 117,667,630 (+)ENTREZGENE
MGSCv377124,524,493 - 124,811,144 (+)RGD
Celera7117,414,249 - 117,605,639 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_783576 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAC18566 (Get FASTA)   NCBI Sequence Viewer  
  CAD62249 (Get FASTA)   NCBI Sequence Viewer  
  EDL17113 (Get FASTA)   NCBI Sequence Viewer  
  Q811B1 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_783576   ⟸   NM_175645
- Peptide Label: precursor
- UniProtKB: Q811B1 (UniProtKB/Swiss-Prot),   F8VPK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000032892   ⟸   ENSMUST00000032892
Protein Domains
Xylo_C

Promoters
RGD ID:8665331
Promoter ID:EPDNEW_M10697
Type:initiation region
Name:Xylt1_1
Description:Mus musculus xylosyltransferase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10698  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387117,381,005 - 117,381,065EPDNEW
RGD ID:8665333
Promoter ID:EPDNEW_M10698
Type:single initiation site
Name:Xylt1_2
Description:Mus musculus xylosyltransferase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10697  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387117,540,332 - 117,540,392EPDNEW
RGD ID:6842349
Promoter ID:MM_KWN:52422
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Kidney,   Lung
Transcripts:OTTMUST00000081402,   OTTMUST00000081403
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367124,524,301 - 124,524,801 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2451073 AgrOrtholog
Ensembl Genes ENSMUSG00000030657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032892 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032892 ENTREZGENE, UniProtKB/TrEMBL
InterPro Glyco_trans_14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Xylosyltrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XylT UniProtKB/Swiss-Prot
  XYLT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XylT_C UniProtKB/TrEMBL
KEGG Report mmu:233781 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2451073 ENTREZGENE
NCBI Gene 233781 ENTREZGENE
PANTHER PTHR46025 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46025:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Branch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Xylo_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xylt1 PhenoGen
UniProt F8VPK6 ENTREZGENE, UniProtKB/TrEMBL
  Q811B1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9EPL1 UniProtKB/Swiss-Prot