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Gene: Nlgn2 (neuroligin 2) Mus musculus
Symbol: Nlgn2
Name: neuroligin 2
Description: Exhibits cell adhesion molecule binding activity; identical protein binding activity; and neurexin family protein binding activity. Involved in several processes, including locomotory exploration behavior; positive regulation of synaptic transmission; and synapse organization. Localizes to several cellular components, including dopaminergic synapse; glycinergic synapse; and integral component of postsynaptic specialization membrane. Used to study schizophrenia. Orthologous to human NLGN2 (neuroligin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC67386; neuroligin-2; NL2; NLG2; ortholog of human and rat neuroligin 2 NLGN2; RP23-422L16.24
Homo sapiens (human) : NLGN2 (neuroligin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nlgn2 (neuroligin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlgn2 (neuroligin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NLGN2 (neuroligin 2)
Canis lupus familiaris (dog) : NLGN2 (neuroligin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlgn2 (neuroligin 2)
Chlorocebus sabaeus (African green monkey) : NLGN2 (neuroligin 2)
Heterocephalus glaber (naked mole-rat) : Nlgn2 (neuroligin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1169,823,122 - 69,837,784 (-)EnsemblGRCm38mm10GRCm38
GRCm381169,823,123 - 69,837,784 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371169,636,625 - 69,648,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,639,318 - 69,651,044 (-)NCBImm8
Celera1177,384,083 - 77,395,807 (-)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nlgn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732706
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.