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Gene: NACC1 (nucleus accumbens associated 1) Homo sapiens
Symbol: NACC1
Name: nucleus accumbens associated 1
Description: This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BEN domain containing 8; BEND8; BTB (POZ) domain containing 14B; BTB/POZ domain-containing protein 14B; BTBD14B; BTBD30; FLJ37383; NAC-1; NAC1; NECFM; nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 1; transcriptional repressor NAC1
Mus musculus (house mouse) : Nacc1 (nucleus accumbens associated 1, BEN and BTB (POZ) domain containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nacc1 (nucleus accumbens associated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nacc1 (nucleus accumbens associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NACC1 (nucleus accumbens associated 1)
Canis lupus familiaris (dog) : NACC1 (nucleus accumbens associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nacc1 (nucleus accumbens associated 1)
Sus scrofa (pig) : NACC1 (nucleus accumbens associated 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381913,116,848 - 13,141,147 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,228,813 - 13,251,961 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,090,109 - 13,112,959 (+)NCBINCBI36hg18NCBI36
Build 341913,090,108 - 13,112,958NCBI
Celera1913,119,516 - 13,142,359 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,818,385 - 12,824,342 (+)NCBIHuRef
CHM1_11913,230,097 - 13,252,914 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NACC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732621
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.