Dbnl (drebrin-like) - Rat Genome Database

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Gene: Dbnl (drebrin-like) Mus musculus
Analyze
Symbol: Dbnl
Name: drebrin-like
RGD ID: 732540
MGI Page MGI
Description: Enables actin filament binding activity and protein domain specific binding activity. Involved in neuron projection morphogenesis; podosome assembly; and synapse assembly. Acts upstream of or within Rac protein signal transduction. Located in several cellular components, including lamellipodium; podosome; and ruffle. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Orthologous to human DBNL (drebrin like).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AB; Abp1; actin-binding protein 1; drebrin-like protein; mAb; mAbp1; SH3; SH3 domain-containing protein 7; SH3P7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,730,233 - 5,750,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,738,488 - 5,750,962 (+)EnsemblGRCm39 Ensembl
GRCm38115,788,483 - 5,800,980 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,788,488 - 5,800,962 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,688,486 - 5,700,983 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,688,533 - 5,700,965 (+)NCBIMGSCv36mm8
Celera116,278,834 - 6,291,141 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory brainstem response  (IEA)
abnormal cardiovascular system physiology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal optic disk morphology  (IEA)
abnormal retina blood vessel morphology  (IEA)
abnormal retina inner nuclear layer morphology  (IEA)
abnormal retina vasculature morphology  (IEA)
abnormal synaptic vesicle recycling  (IAGP)
abnormal T cell activation  (IAGP)
abnormal T cell physiology  (IAGP)
convulsive seizures  (IAGP)
decreased body weight  (IAGP)
decreased circulating alkaline phosphatase level  (IEA)
decreased circulating cholesterol level  (IEA)
decreased circulating HDL cholesterol level  (IEA)
decreased circulating serum albumin level  (IEA)
decreased circulating total protein level  (IEA)
decreased circulating triglyceride level  (IEA)
decreased erythrocyte cell number  (IEA)
decreased hematocrit  (IEA)
decreased hemoglobin content  (IEA)
decreased IgG1 level  (IAGP)
decreased IgM level  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased interleukin-2 secretion  (IAGP)
decreased locomotor activity  (IEA)
decreased T cell proliferation  (IAGP)
decreased total retina thickness  (IEA)
emphysema  (IAGP)
generalized edema  (IAGP)
hindlimb paralysis  (IAGP)
impaired coordination  (IAGP)
impaired swimming  (IAGP)
increased circulating glucose level  (IEA)
increased fluid intake  (IEA)
increased grip strength  (IEA)
increased heart weight  (IEA)
increased mean corpuscular hemoglobin  (IEA)
increased mean corpuscular volume  (IEA)
increased spleen weight  (IAGP)
increased startle reflex  (IEA)
limb grasping  (IAGP)
paresis  (IAGP)
persistence of hyaloid vascular system  (IEA)
prenatal lethality, incomplete penetrance  (IAGP)
respiratory distress  (IAGP)
ruffled hair  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9126384   PMID:9630982   PMID:9891087   PMID:10087302   PMID:10349636   PMID:10613908   PMID:10637315   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199  
PMID:12477932   PMID:12520002   PMID:12913069   PMID:14729663   PMID:15489334   PMID:15782199   PMID:15848169   PMID:16055701   PMID:16141072   PMID:16141073   PMID:16601697   PMID:16602821  
PMID:16944949   PMID:17956734   PMID:18453588   PMID:18799693   PMID:18829961   PMID:19064729   PMID:19208628   PMID:19638624   PMID:19910490   PMID:21267068   PMID:21565611   PMID:21677750  
PMID:21873635   PMID:22303001   PMID:22450813   PMID:22922362   PMID:23223303   PMID:24958882   PMID:28378742   PMID:30196744   PMID:30504273   PMID:32325033   PMID:32554809   PMID:32581705  
PMID:34321999   PMID:36417873  


Genomics

Comparative Map Data
Dbnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,730,233 - 5,750,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,738,488 - 5,750,962 (+)EnsemblGRCm39 Ensembl
GRCm38115,788,483 - 5,800,980 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,788,488 - 5,800,962 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,688,486 - 5,700,983 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,688,533 - 5,700,965 (+)NCBIMGSCv36mm8
Celera116,278,834 - 6,291,141 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
DBNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,044,702 - 44,069,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,044,640 - 44,069,456 (+)EnsemblGRCh38hg38GRCh38
GRCh37744,084,301 - 44,109,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,050,830 - 44,067,840 (+)NCBINCBI36Build 36hg18NCBI36
Celera744,182,185 - 44,199,260 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,969,523 - 43,986,598 (+)NCBIHuRef
CHM1_1744,088,113 - 44,105,189 (+)NCBICHM1_1
T2T-CHM13v2.0744,203,197 - 44,227,954 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,123,733 - 44,140,805 (+)NCBI
Dbnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBICelera
Cytogenetic Map14q21NCBI
Dbnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,912,827 - 7,924,787 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,912,827 - 7,924,373 (-)NCBIChiLan1.0ChiLan1.0
DBNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,950,223 - 48,972,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,276,140 - 97,297,574 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,753,062 - 44,775,717 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,824,537 - 44,842,059 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,824,608 - 44,845,891 (+)Ensemblpanpan1.1panPan2
DBNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha161,996,510 - 2,007,305 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,854,694 - 14,865,499 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,854,694 - 14,877,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,485,876 - 14,496,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,466,360 - 14,477,156 (-)NCBIUU_Cfam_GSD_1.0
Dbnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,795,888 - 99,809,337 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,007,672 - 19,020,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,007,630 - 19,021,068 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,713,340 - 48,725,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,713,335 - 48,725,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,426,424 - 53,438,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DBNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,610,196 - 14,627,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dbnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,950,556 - 7,960,568 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,950,552 - 7,960,592 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dbnl
633 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:684
Count of miRNA genes:319
Interacting mature miRNAs:343
Transcripts:ENSMUST00000020769, ENSMUST00000102928, ENSMUST00000109845
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001146308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK037484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL627069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY098595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM247511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY293844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000020769   ⟹   ENSMUSP00000020769
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,738,522 - 5,750,288 (+)Ensembl
GRCm38.p6 Ensembl115,788,522 - 5,800,288 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102928   ⟹   ENSMUSP00000099992
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,738,530 - 5,750,962 (+)Ensembl
GRCm38.p6 Ensembl115,788,530 - 5,800,962 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109845   ⟹   ENSMUSP00000105471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,738,488 - 5,750,629 (+)Ensembl
GRCm38.p6 Ensembl115,788,488 - 5,800,629 (+)Ensembl
RefSeq Acc Id: NM_001146308   ⟹   NP_001139780
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,738,483 - 5,750,980 (+)NCBI
GRCm38115,788,483 - 5,800,980 (+)ENTREZGENE
MGSCv37115,688,486 - 5,700,983 (+)RGD
Celera116,278,834 - 6,291,141 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001146309   ⟹   NP_001139781
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,738,483 - 5,750,980 (+)NCBI
GRCm38115,788,483 - 5,800,980 (+)ENTREZGENE
MGSCv37115,688,486 - 5,700,983 (+)RGD
Celera116,278,834 - 6,291,141 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_013810   ⟹   NP_038838
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,738,483 - 5,750,980 (+)NCBI
GRCm38115,788,483 - 5,800,980 (+)ENTREZGENE
MGSCv37115,688,486 - 5,700,983 (+)RGD
Celera116,278,834 - 6,291,141 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156280   ⟹   XP_036012173
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,730,233 - 5,750,976 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001139780 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139781 (Get FASTA)   NCBI Sequence Viewer  
  NP_038838 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012173 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52640 (Get FASTA)   NCBI Sequence Viewer  
  AAH46430 (Get FASTA)   NCBI Sequence Viewer  
  AAM28340 (Get FASTA)   NCBI Sequence Viewer  
  BAC32592 (Get FASTA)   NCBI Sequence Viewer  
  BAC35528 (Get FASTA)   NCBI Sequence Viewer  
  BAC37118 (Get FASTA)   NCBI Sequence Viewer  
  BAE22028 (Get FASTA)   NCBI Sequence Viewer  
  BAE22160 (Get FASTA)   NCBI Sequence Viewer  
  BAE24466 (Get FASTA)   NCBI Sequence Viewer  
  BAE25201 (Get FASTA)   NCBI Sequence Viewer  
  BAE27532 (Get FASTA)   NCBI Sequence Viewer  
  BAE30108 (Get FASTA)   NCBI Sequence Viewer  
  BAE31033 (Get FASTA)   NCBI Sequence Viewer  
  BAE31953 (Get FASTA)   NCBI Sequence Viewer  
  BAE35535 (Get FASTA)   NCBI Sequence Viewer  
  BAE40714 (Get FASTA)   NCBI Sequence Viewer  
  BAE43024 (Get FASTA)   NCBI Sequence Viewer  
  EDL40554 (Get FASTA)   NCBI Sequence Viewer  
  EDL40555 (Get FASTA)   NCBI Sequence Viewer  
  EDL40556 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020769
  ENSMUSP00000020769.8
  ENSMUSP00000099992
  ENSMUSP00000099992.5
  ENSMUSP00000105471
  ENSMUSP00000105471.2
GenBank Protein Q62418 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_038838   ⟸   NM_013810
- Peptide Label: isoform 2
- UniProtKB: Q62418 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001139780   ⟸   NM_001146308
- Peptide Label: isoform 1
- UniProtKB: Q80WP1 (UniProtKB/Swiss-Prot),   Q5NCI7 (UniProtKB/Swiss-Prot),   Q5NCI6 (UniProtKB/Swiss-Prot),   Q5NCI5 (UniProtKB/Swiss-Prot),   Q3UZ33 (UniProtKB/Swiss-Prot),   Q3U8I5 (UniProtKB/Swiss-Prot),   Q3U5X3 (UniProtKB/Swiss-Prot),   Q3TG34 (UniProtKB/Swiss-Prot),   Q8BH56 (UniProtKB/Swiss-Prot),   Q62418 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001139781   ⟸   NM_001146309
- Peptide Label: isoform 3
- UniProtKB: Q62418 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020769   ⟸   ENSMUST00000020769
RefSeq Acc Id: ENSMUSP00000105471   ⟸   ENSMUST00000109845
RefSeq Acc Id: ENSMUSP00000099992   ⟸   ENSMUST00000102928
RefSeq Acc Id: XP_036012173   ⟸   XM_036156280
- Peptide Label: isoform X1
- UniProtKB: Q80WP1 (UniProtKB/Swiss-Prot),   Q62418 (UniProtKB/Swiss-Prot),   Q5NCI7 (UniProtKB/Swiss-Prot),   Q5NCI6 (UniProtKB/Swiss-Prot),   Q5NCI5 (UniProtKB/Swiss-Prot),   Q3UZ33 (UniProtKB/Swiss-Prot),   Q3U8I5 (UniProtKB/Swiss-Prot),   Q3U5X3 (UniProtKB/Swiss-Prot),   Q3TG34 (UniProtKB/Swiss-Prot),   Q8BH56 (UniProtKB/Swiss-Prot)
Protein Domains
ADF-H   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62418-F1-model_v2 AlphaFold Q62418 1-436 view protein structure

Promoters
RGD ID:6820699
Promoter ID:MM_KWN:6314
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001146308,   NM_001146309,   NM_013810
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,688,184 - 5,688,684 (+)MPROMDB
RGD ID:6846826
Promoter ID:MM_ACW:6643
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:DBNL.FSEP07,   DBNL.ISEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,696,811 - 5,697,311 (+)MPROMDB
RGD ID:8673860
Promoter ID:EPDNEW_M14960
Type:initiation region
Name:Dbnl_1
Description:Mus musculus drebrin-like , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38115,788,517 - 5,788,577EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:700006 AgrOrtholog
Ensembl Genes ENSMUSG00000020476 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020769 ENTREZGENE
  ENSMUST00000020769.14 UniProtKB/Swiss-Prot
  ENSMUST00000102928 ENTREZGENE
  ENSMUST00000102928.5 UniProtKB/Swiss-Prot
  ENSMUST00000109845 ENTREZGENE
  ENSMUST00000109845.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
InterPro ADF-H UniProtKB/Swiss-Prot
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot
  Drebrin-like_SH3 UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report mmu:13169 UniProtKB/Swiss-Prot
MGD MGI:700006 ENTREZGENE
NCBI Gene 13169 ENTREZGENE
PANTHER CORTACTIN AND DREBRIN UniProtKB/Swiss-Prot
  PTHR10829:SF12 UniProtKB/Swiss-Prot
Pfam Cofilin_ADF UniProtKB/Swiss-Prot
  SH3_9 UniProtKB/Swiss-Prot
PhenoGen Dbnl PhenoGen
PROSITE ADF_H UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
SMART ADF UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
UniProt DBNL_MOUSE UniProtKB/Swiss-Prot
  Q3TG34 ENTREZGENE
  Q3U5X3 ENTREZGENE
  Q3U8I5 ENTREZGENE
  Q3UZ33 ENTREZGENE
  Q5NCI5 ENTREZGENE
  Q5NCI6 ENTREZGENE
  Q5NCI7 ENTREZGENE
  Q62418 ENTREZGENE
  Q80WP1 ENTREZGENE
  Q8BH56 ENTREZGENE
UniProt Secondary Q3TG34 UniProtKB/Swiss-Prot
  Q3U5X3 UniProtKB/Swiss-Prot
  Q3U8I5 UniProtKB/Swiss-Prot
  Q3UZ33 UniProtKB/Swiss-Prot
  Q5NCI5 UniProtKB/Swiss-Prot
  Q5NCI6 UniProtKB/Swiss-Prot
  Q5NCI7 UniProtKB/Swiss-Prot
  Q80WP1 UniProtKB/Swiss-Prot
  Q8BH56 UniProtKB/Swiss-Prot